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5 056 (0,195s) •

Project

Pathological expansion of microsatellites in the human genome. (NR9147)

1, Identification of regions in the human genome most prone to expansion by means of bioinformatic analysis. 2, PCR of these regions to assess their propensity to expansion. 3, Biophysical analysis of the expanding fragments to iden...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 2 336 tis. Kč
    • •
  • 2 336 tis. Kč
    • •
  • MZ
Project

Biophysical analysis of selected regions of the human genome (IAA5004802)

in the human genome. We will further write a software comparing distribution of the conformational properties of DNA along the human genome with the distribution of the oligonucleotides coding for these properties...

BO - Biofyzika

  • 1998 - 2002
    • •
  • 7 736 tis. Kč
    • •
  • 2 387 tis. Kč
    • •
  • AV ČR
Project

Development of a method for prediction of pathological expansions of trinucleotide repeats in the human genome (NM7634)

that the common PCR in vitro simulates the pathological microsatellite expansions in the human genome. We will use PCr and human genome bioinformatics for purpose. Perform PCR pathologically expanding human

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 4 688 tis. Kč
    • •
  • 2 063 tis. Kč
    • •
  • MZ
Project

Development of a method for conformational mapping of the human genome regions of medical interest (GA302/98/P112)

Development of a method for conformational mapping of the human genome regions of medical interest. Project terminated, because the applicant changed the employer.......

EB - Genetika a molekulární biologie

  • 1998 - 1998
    • •
  • 431 tis. Kč
    • •
  • 238 tis. Kč
    • •
  • GA ČR
Project

Biophysical properties of the (guanine+cytosine) blocks and the (adenine+thymine) blocks in the human chromosome molecules of DNA (IAA1004201)

of the human genome. Identify nucleotide sequences introducing RNA-like properties into DNA and the human genome regions sensitive to UV light damage. Take use of the sensitivity for their secondary structure mode...

BO - Biofyzika

  • 2002 - 2006
    • •
  • 6 327 tis. Kč
    • •
  • 3 013 tis. Kč
    • •
  • AV ČR
Project

Biophysics and bioinformatics of the regions in the human genome with extreme nucleotide distributions (GA202/07/0094)

Our preliminary results show that the human genome contains surprisingly large toidentify the extremely biased  regions by bioinformatic methods in the human, chimp, mouse and other genomes and their representative...

BO - Biofyzika

  • 2007 - 2009
    • •
  • 2 815 tis. Kč
    • •
  • 2 815 tis. Kč
    • •
  • GA ČR
Project

Tetraplexes of DNA and Their Occurrence in the Human Genome (IAA4004201)

Tetraplex is a biologically active alternative of the DNA double helix. Studies of, so far, a small part of the human genome indicate that it contains thousands of sequences prone to tetraplex formation. In this project, we wuggest ...

CE - Biochemie

  • 2002 - 2006
    • •
  • 5 078 tis. Kč
    • •
  • 2 524 tis. Kč
    • •
  • AV ČR
Project

Nuclear topology of cell genome (GA304/00/1622)

patterns of 3D genome organization in the interphase nuclei of human and mouse fibroplasts. By means of 3D FISH and 3D ZOO-FISH with human and mouse centromere of a sample of orthologous chromosomal segments of human

EA - Morfologické obory a cytologie

  • 2000 - 2002
    • •
  • 4 729 tis. Kč
    • •
  • 2 309 tis. Kč
    • •
  • GA ČR
Project

Human Resources Development for R&D and Innovation in the Field of Genomics and Proteomics of Plant Systems (EE2.3.20.0043)

The aim is to prepare human resources for the expansion of research in selected areas of genomics and proteomics of plant systems. The project aims to support the creation of research teams in the field of developmental and cell bio...

EF - Botanika

  • 2011 - 2014
    • •
  • 23 214 tis. Kč
    • •
  • 23 214 tis. Kč
    • •
  • MŠMT
Project

Functional genomics of the nuclear hormone receptor transcription complex in human tumors (NC7554)

Functional genomics targeted on components of transcription complex of RNA Polymerase II order to improve diagnostics and therapy of tumors.......

FC - Pneumologie

  • 2003 - 2005
    • •
  • 4 353 tis. Kč
    • •
  • 4 325 tis. Kč
    • •
  • MZ
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