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1 609 (0,161s)

Project

Parallel detection of major potato viral pathogens by means of hybridization methods (GA522/01/1105)

The aim of the project is preparation of a hybridization assay with parallel treatment of samples covering simultaneously, on a single hybridization array, the most important potato viruses: PVY-0, PVY-V, PVY-NTN, PVX, PVS,...

CF - Fyzikální chemie a teoretická chemie

  • 2001 - 2003
  • 5 038 tis. Kč
  • 2 882 tis. Kč
  • GA ČR
Project

Targeted chemotherapy towards diseases caused by endoparasites (LD15081)

and hybrid drugs will be prepared and assayed for their hepatoprotective potential new hybrid drugs with decreased adverse effects. Next aim is to confirm newly silymarin (silybin is available in large quantities). All the...

CC - Organická chemie

  • 2015 - 2017
  • 1 322 tis. Kč
  • 1 322 tis. Kč
  • MŠMT
Project

Synthesis and evaluation of azaphthalocyanine derivatives as fluorescence quenchers (KJB401100801)

hybridization assays. Both static and dynamic (FRET) quenching will be tested....

CC - Organická chemie

  • 2008 - 2010
  • 2 327 tis. Kč
  • 2 327 tis. Kč
  • AV ČR
Project

Azaphthalocyanines – dark quenchers in DNA hybridization probes (GA17-19094S)

This project on boundary of chemistry, physics and molecular biology aims at investigation of novel highly prospective dark quenchers with azaphthalocyanine (AzaPc) core for DNA hybridization assays in double-labeled probes. The Aza...

CC - Organická chemie

  • 2017 - 2021
  • 5 890 tis. Kč
  • 5 890 tis. Kč
  • GA ČR
Project

Positional cloning of the Hybrid sterility 1 gene (IAA5052709)

The proposed project is aimed at positional cloning of Hybrid sterility 1 gene and initiation of its molecular and functional characterization. The project is structured transgene gene will be verified by checking fertility of F+ hybrid<...

EB - Genetika a molekulární biologie

  • 1997 - 2001
  • 3 604 tis. Kč
  • 2 595 tis. Kč
  • AV ČR
Project

Application of molecular method for improving the hereditary health checks in farm animals (QC1197)

by florescence in situ hybridization (FISH). The Sperm Chromatin Structure Assay (SCSA...

EB - Genetika a molekulární biologie

  • 2001 - 2005
  • 2 900 tis. Kč
  • 2 900 tis. Kč
  • MZe
Project

Impact of environmental and genetic factors on men fertility (1QS500390506)

diagnostic method "Sperm Chromatin Structure Assay" will be introduced into applied...

DN - Vliv životního prostředí na zdraví

  • 2005 - 2008
  • 9 752 tis. Kč
  • 9 752 tis. Kč
  • AV ČR
Project

Basic biology of crayfish sperm with emphasis on the molecular and morphological modifications during capacitation and acrosome reaction (GPP502/12/P177)

assays. Concerning that neither capacitation nor acrozome reaction has not been a practical and reliable sperm quality assay as well as improving knowledge on sperm maturation, possible hybridization barriers, and represen...

ED - Fyziologie

  • 2012 - 2014
  • 1 747 tis. Kč
  • 1 747 tis. Kč
  • GA ČR
Project

Chemical modification and electrochemical analysis of nucleic acids as a new tool in molecular oncology (GA17-08971S)

to develop electrochemical assays for detection of DNA and RNA sequences, as well and tumor suppressors. Moreover, we want to develop an assay for discrimination......

CG - Elektrochemie

  • 2017 - 2019
  • 6 782 tis. Kč
  • 6 356 tis. Kč
  • GA ČR
Project

Cytogenetic markers of tumor cells responsiveness to anti-cancer drugs (NC7495)

The project is focused on the molecular cytogenetic assessment by use of locus specific DNA probes (FISH) and comparative genomic hybridization (CGH) technique in order to find different correlation of drug resistance and cytogenetic finding...

FR - Farmakologie a lékárnická chemie

  • 2003 - 2005
  • 4 009 tis. Kč
  • 4 009 tis. Kč
  • MZ
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