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5 (0,111s)

Project

3-Hydroxyquinolin-4(1H)-ones as biologically interesting molecules (GJ18-26557Y)

The project deals with 3-hydroxyquinolin-4(1H)-ones (3-HQs) as compounds with interesting biological properties. In the first part, their anticancer properties are discussed. It was found out that some 3-HQ derivatives interact with translat...

Organic chemistry

  • 2018 - 2020
  • 4 620 tis. Kč
  • 4 620 tis. Kč
  • GA ČR
Project

Synthesis and biological activity of 2-aryl-3hydroxyquinolin-4(1H)-ones derivatives (GA203/01/1360)

2-Aryl-3-hydroxyquinoline-4(lH)-ones are isoster with flavones. On the other hand, they are less studied from synthetic as well as biological point of view. In recent years we have found an original way of their synthesis. As we supposed, a ...

CC - Organická chemie

  • 2001 - 2003
  • 1 212 tis. Kč
  • 1 212 tis. Kč
  • GA ČR
Project

Polymer supports cintaining immobilized metal ions for protein purification (IAA4050910)

The immobilized metal ion affinity chromatography (IMAC) of monoclonal antibodies (mAbs) and transgenic proteins are stdied. New hydrophylic polymer supports modified with various chelating ligands and coordinated with transition or hard Lewis metal ...

CD - Makromolekulární chemie

  • 1999 - 2001
  • 3 601 tis. Kč
  • 1 054 tis. Kč
  • AV ČR
Project

Modern methods for the synthesis of quinolones for pharmaceutical intermediates (FV20250)

-hydroxyquinolin-4(1H)-ones derivatives synthesis and characterisation....

CC - Organická chemie

  • 2017 - 2021
  • 19 963 tis. Kč
  • 14 801 tis. Kč
  • MPO
Project

Polymeric micelles with metal ion ? assembled core (GPP207/10/P054)

, containing hydroxamic acid and 8-hydroxyquinoline chelating moieties in the backbone...

CD - Makromolekulární chemie

  • 2010 - 2012
  • 1 185 tis. Kč
  • 1 185 tis. Kč
  • GA ČR
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