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31 (0,088s)

Project

Immune reactions in food hypersensitivity and possibilities of their modulation (NI5467)

Development of mouse model of food hypersensitivity. Antiallergen antibody detection. Testing of blast transformation, cytokine formation and mast cell degranulation after stimulation by allergen.Modulation of hypersensitivity by or...

EC - Imunologie

  • 1999 - 2001
  • 1 864 tis. Kč
  • 1 864 tis. Kč
  • MZ
Project

Study of the effects of elicitins stimulating a defence reacions in plants. (ME 321)

Elicitins are proteins secreted by Oomycetes and stimulating defence reaction in plants (hypersensitive reaction with non specific systemic acquired resistence). Moreover, they are a part of group of sterol carrier proteins. They are probaly...

CE - Biochemie

  • 1999 - 2001
  • 1 093 tis. Kč
  • 779 tis. Kč
  • MŠMT
Project

Use of lymphocytes of hypersensitive patients for preclinical testing of advanced titanium-based materials modified by ion beam (NV19-08-00070)

of hypersensitivity - type IV. immunopathologic reaction. The purpose of this project is to modify these materials using T-lymphocytes isolated from the peripheral blood of hypersensitive standard cell lines. Due to the growing inc...

Materials engineering

  • 2019 - 2023
  • 10 335 tis. Kč
  • 10 288 tis. Kč
  • MZ
Project

Food allergy to wheat proteins (IAA500200801)

food allergens inducing IgE-mediated hypersensitivity manifesting as cutaneous, only a few wheat proteins causing hypersensitivity reactions have been identified the course of allergy treatment. The mechanism of hypersensitivit...

EC - Imunologie

  • 2008 - 2011
  • 4 667 tis. Kč
  • 4 667 tis. Kč
  • AV ČR
Project

Immunogenomic analysis of insect bite hypersensitivity in the Old Kladruber horse (GA524/09/1939)

Insect bite hypersensitivity in horses is allergic disorder that arises from hypersensitivity reactions to insect bite. The immune response  is polarized to Th2 in IBH. Genetic architecture of allergic disorders in horses  is not qu...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2009 - 2011
  • 1 736 tis. Kč
  • 1 736 tis. Kč
  • GA ČR
Project

Expresion of gonadotropin-receptors in normal and precocious puberty in girls (NH7663)

We would like to clarify the distribution and number of the ovarial receptors for FSH, LH and steroid hormones in various detected follicular evolutional stages during normal pubertal development. The results of our study could support our theory tha...

FK - Gynekologie a porodnictví

  • 2003 - 2005
  • 1 406 tis. Kč
  • 1 276 tis. Kč
  • MZ
Project

Biological interactions of corrosion products of dental alloys (NT12206)

The physico-chemical characteristics of an oral environment of patients with dental alloys and with the diagnosis of metal hypersensitivity will be determined by means of modified LTT. Detection of cytokines produced by mononuclear cells (MC...

FF - ORL, oftalmologie, stomatologie

  • 2011 - 2014
  • 3 511 tis. Kč
  • 3 511 tis. Kč
  • MZ
Project

Multicentric evaluation of hypersensitivity reactions in patients indicated for total joint replacement including evaluation of the reasons for reimplanting (NU20-08-00149)

with the activation of the immune system, including hypersensitivity reactions, will be simulated...

Orthopaedics

  • 2020 - 2023
  • 14 006 tis. Kč
  • 14 006 tis. Kč
  • MZ
Project

Pathogenesis of primoinfection and reinfection with bird schistosome cercariae (NJ6718)

The pathogenesis of primoinfection and reinfection with Trichobilharzia szidati and Bilharziella polonica cercariae in a nonspecific host.Major antigens in immune response. Importance of the hypersensitive reaction.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2001 - 2003
  • 1 276 tis. Kč
  • 1 274 tis. Kč
  • MZ
Project

Cellular and molecular characterization of abnormal signaling in primary polycythemia (GAP301/12/1503)

Erythroid progenitors in primary polycythemia exhibit in vitro hypersensitivity to erythropoietin due to dysregulation of signaling pathways, which under physiological conditions mediate cellular responses to cytokines. We will test our hypo...

FD - Onkologie a hematologie

  • 2012 - 2016
  • 6 776 tis. Kč
  • 6 776 tis. Kč
  • GA ČR
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