All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

1 620 (0,095s) •

Project

Mechanisms of protective immunity against tumours with different expression of immunodulatory molecules (IAA500520807)

class I and other immunomodulatory molecules, used as cellular vaccines against variants of tumours with different expression of these molecules. (2) Immunization and distinct in the expression of selected immunomodula...

FD - Onkologie a hematologie

  • 2008 - 2010
    • •
  • 2 800 tis. Kč
    • •
  • 2 800 tis. Kč
    • •
  • AV ČR
Project

Development and testing of novel perspective antivirals and their prodrug forms active against tick-borne encephalitis virus (NV16-34238A)

. We will experimentally combine these antiviral molecules with immunomodulatory molecules into prodrug forms with increased therapeutical potential based on efficient and important data about the possibilities and directio...

EE - Mikrobiologie, virologie

  • 2016 - 2019
    • •
  • 8 950 tis. Kč
    • •
  • 8 950 tis. Kč
    • •
  • MZ
Project

Effect of tick saliva on signalling pathways activated by Borrelia pathogen in dendritic cells (GAP302/12/2208)

Tick saliva contains immunomodulatory molecules which facilitate both, blood feeding and transmission of tick-borne pathogens. Although many of these molecules have been identified, little is known about mechanisms of these...

EC - Imunologie

  • 2012 - 2015
    • •
  • 7 315 tis. Kč
    • •
  • 5 843 tis. Kč
    • •
  • GA ČR
Project

Identification of tick salivary molecules facilitating transmission of Borrelia burgdorferi using RNA interference (IAA600960811)

been identified. It is very likely that immunomodulatory (immunosuppressive) molecules in tick saliva are responsible for SAT effect. The main objective. Recombinant proteins will be produced and tested for the SAT and immunomo...

EC - Imunologie

  • 2008 - 2010
    • •
  • 3 228 tis. Kč
    • •
  • 3 228 tis. Kč
    • •
  • AV ČR
Project

Identification and functional characterization of bioactive molecules produced by entomopathogenic nematodes (GA23-06457S)

and other immune-modulating molecules. The main goal of the project is the identification of molecules in the secretome of the nematode Heterorhabditis bacteriophora presence of many active molecules affecting the host imm...

Biochemistry and molecular biology

  • 2023 - 2025
    • •
  • 9 987 tis. Kč
    • •
  • 9 987 tis. Kč
    • •
  • GA ČR
Project

IMMUNOMODULATORY EFFECTS OF TICK CYSTATINS (KJB500960702)

Tick saliva has been proven to facilitate transmission of important human pathogens via the actions of bioactive molecules on the host immunity. Whereas the general effect of tick saliva on host immune mechanisms was characterised, little in...

EC - Imunologie

  • 2007 - 2009
    • •
  • 1 350 tis. Kč
    • •
  • 1 350 tis. Kč
    • •
  • AV ČR
Project

Tick saliva-activated transmission of important pathogens (GA524/05/0811)

pathogens via the actions of bioactive molecules on the vertebrate host. Although several candidate molecules for this saliva-activated transmission (SAT) were proposed molecules on the basis of tick saliva effect on mecha...

EC - Imunologie

  • 2005 - 2007
    • •
  • 2 850 tis. Kč
    • •
  • 2 850 tis. Kč
    • •
  • GA ČR
Project

Anti-hemostatic serpins from the tick Ixodes ricinus and their role in pathogen transmission (GJ19-14704Y)

, the ticks secrete via their saliva wide range of pharmacoactive molecules that prevent for their anti-hemostatic, anti-inflammatory and immunomodulatory properties and block them in the development of novel anti-hemostatic and/or ...

Biochemistry and molecular biology

  • 2019 - 2023
    • •
  • 7 739 tis. Kč
    • •
  • 7 739 tis. Kč
    • •
  • GA ČR
Project

Immunomodulatory potencies of toxic cyanobacteria (GP13-27695P)

Massive growth of cyanobacterial water blooms became one of the most serious environmental and health problems worldwide. Cyanobacteria produce many biologically active metabolites including several inflammatory and immunomodulatory agents, ...

DJ - Znečištění a kontrola vody

  • 2013 - 2015
    • •
  • 2 021 tis. Kč
    • •
  • 2 021 tis. Kč
    • •
  • GA ČR
Project

Leishmania transmission by sand flies parasite-vector-host interaction (GA206/06/0967)

and immunomodulatory molecules and enhance the initial phase of Leishmania infection. In addition is aimed at different molecules involved in Leishmania transmission and in parasite......

EG - Zoologie

  • 2006 - 2008
    • •
  • 3 098 tis. Kč
    • •
  • 3 098 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 1 620