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Projects

8 projects (0,144s)

Project

The risk of hypothalamo-pituitary-thyroid axis maldevelopment as a consequence of perinatal glucocorticoid and indomethacine administration. (IZ4291)

The impact of perinatal administration of indomethacine and dexamethazone on the development and adult function of hypothalamo-pituitary-thyroid axis will be studies in model experiments with rats. Following markers will be used monoamine tu...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1997 - 1999
  • 1 521 tis. Kč
  • 1 084 tis. Kč
  • MZ
Project

Comparison of Ibuprofen and Indomethacine in the treatment hemodynamic significant patent ductus arteriosus /PDA/ in the newborns wtih extremely and very low bi (NE4748)

The hemodynamic significant PDA may lead to an increased risk for long term morbidity in low birthweight newborns.Currently used indomethacine therapy has been implicated in several adverse effects. The aim of our study is the avalution of i...

FG - Pediatrie

  • 1998 - 2000
  • 1 601 tis. Kč
  • 1 177 tis. Kč
  • MZ
Project

International presentation of grant research results Functional teratogenic risk of indomethacine. (PG98151)

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FH - Neurologie, neurochirurgie, neurovědy

  • 1998 - 1998
  • 90 tis. Kč
  • 60 tis. Kč
  • MŠMT
Project

Risk of persistent neuro-immuno-behavioural deviations induced by perinatal administration of indomethacine. (IZ4014)

Indomethacine, used in risk newborns for prevention of intraventricular hemorrhage and eccelerated closure of patent ductus arteriosus is studied for functional teratogenicity in model experiments in rats with lifelong monitoring of defects....

FH - Neurologie, neurochirurgie, neurovědy

  • 1997 - 1999
  • 6 384 tis. Kč
  • 3 736 tis. Kč
  • MZ
Project

Suppression of free radicals generation at reperfusion injury as a part of prevention of development MODS (IZ3003)

FP - Ostatní lékařské obory

  • 1995 - 1997
  • 580 tis. Kč
  • 561 tis. Kč
  • MZ
Project

Blocking SIRS (Systemic inflammatory response syndrome) in severe thoracic trauma patients (ND7029)

The subject of the work is systemic inflammatory response of the organism in severe chest injuries. The aim of the project is to verify the efficacy of early pharmacological intervention in blocking SIRS. Administration of indomethacin as an...

FI - Traumatologie a ortopedie

  • 2002 - 2004
  • 1 762 tis. Kč
  • 1 552 tis. Kč
  • MZ
Project

Influence of seminal immunosuppressor on humoral immune reaction of an organism (GA204/98/0827)

and the nosteroid inhibitor of inflammation - indomethacin - on the antiproliferative effect...

EC - Imunologie

  • 1998 - 2000
  • 1 590 tis. Kč
  • 1 590 tis. Kč
  • GA ČR
Project

The influence of experimental gastrointestinal injury and inflammation on pharmacokinetics of Alzheimer's disease drugs (GA18-13283S)

injury induced by dextran-sodium sulphate or indomethacin). The second objective...

Gastroenterology and hepatology

  • 2018 - 2022
  • 10 685 tis. Kč
  • 10 397 tis. Kč
  • GA ČR
  • 1 - 8 out of 8