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786 (0,06s) •

Project

The role of pH in the development and differentiation of multicellular yeast populations (LTC20036)

approaches for in situ, intracellular pH measurement in multicellular yeast populations - colonies and biofilms, and to uncover the effect of intracellular pH in regulating also aims to acquire new knowledge regar...

Microbiology

  • 2020 - 2023
    • •
  • 7 285 tis. Kč
    • •
  • 7 285 tis. Kč
    • •
  • MŠMT
Project

Regulation of intracellular pH, calcium and potassium homeostases in budding yeast (LH14297)

The project aims to contribute to the understanding of the role of calcium and potassium homeostases and transport in the regulation of intracellular pH in the model yeast Saccharomyces cerevisiae.......

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 1 892 tis. Kč
    • •
  • 1 892 tis. Kč
    • •
  • MŠMT
Project

Intracellular and extracellular targets for antitumor activity and toxicity of ruthenium complexex (1P05OC070)

complexex of rhutenium as a new class of promising cytostatics effective in tumor cell resistant to platinum cytostatics...

FR - Farmakologie a lékárnická chemie

  • 2005 - 2006
    • •
  • 705 tis. Kč
    • •
  • 522 tis. Kč
    • •
  • MŠMT
Project

Application of fluorescence methods to estimate the role of potassium transporters in the regulation of membrane potential and intracellular pH of yeast cells (KJB500110701)

and intracellular pH. The mail goal of this project is establishing a new method of fluorescence spectroscopy of cellular pH and membrane potential, using the diS-C3(3) fluorescence probe physiological processes of yeast c...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 1 349 tis. Kč
    • •
  • 1 349 tis. Kč
    • •
  • AV ČR
Project

Intracellular pH and alkali-metal-cation homeostasis in Candida virulence and pathogenicity (GAP302/12/1151)

that includes an efficient regulation of intracellular K+ and pH homeostases. These two in the maintenance of potassium homeostasis, membrane potential and intracellular pH biogenesis, maintenance of membrane pote...

EE - Mikrobiologie, virologie

  • 2012 - 2015
    • •
  • 5 402 tis. Kč
    • •
  • 5 402 tis. Kč
    • •
  • GA ČR
Project

Extracellular pH modulates neuronal activity, neuronal plasticity and epileptic seizures (GA305/95/0588)

ED - Fyziologie

  • 1995 - 1997
    • •
  • 2 094 tis. Kč
    • •
  • 2 094 tis. Kč
    • •
  • GA ČR
Project

Transport systems involved in intracellular pH homeostasis and yeast tolerance to low external pH (LTC20006)

and pH homeostasis in yeast cells. Further, new knowledge will help to identify transporters whose engineering may improve the robustness of intracellular pH homeostasis together with the tolerance of yeast cells to growth...

Microbiology

  • 2020 - 2023
    • •
  • 4 326 tis. Kč
    • •
  • 4 326 tis. Kč
    • •
  • MŠMT
Project

Role of Na/H antiporters in cell physiology - transporters teamwork in intracellular pH and K+ homeostasis (IAA500110801)

Na+/H+ antiporters serve in all organisms mainly to maintain intracellular homeostasis of alkali metal cations and pH. In the model yeast Saccharomyces cerevisiae, three members of the family exist: Nha1p is in the plasma membrane, ...

EB - Genetika a molekulární biologie

  • 2008 - 2012
    • •
  • 4 020 tis. Kč
    • •
  • 4 020 tis. Kč
    • •
  • AV ČR
Project

SW analysis of changes in microscopic images of cell structures using fluorescence indicators (TA01011467)

The aim of this project is to produce a user-friendly and low-cost software enabling automated analysis of cell granularity and intracellular pH. The SW function will be tested and validated on microscopy images of yeast cells. To c...

JC - Počítačový hardware a software

  • 2011 - 2012
    • •
  • 8 688 tis. Kč
    • •
  • 6 921 tis. Kč
    • •
  • TA ČR
Project

Physiological role of cation/proton antiporters in monovalent cation homeostasis, Ca2+ signalling and intracellular pH regulation (GA17-01953S)

The tight regulation of intracellular ion concentrations is crucial for all cells. Optimal levels of cations are ensured by the coordinated activity of various transporters. If the activity of ion transporters and consequently ion homeostasi...

EE - Mikrobiologie, virologie

  • 2017 - 2019
    • •
  • 5 032 tis. Kč
    • •
  • 4 762 tis. Kč
    • •
  • GA ČR
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