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Projects

106 projects (0,21s) •

Project

Ischemia modified albumin and circulating microRNAs as a new technology for monitoring of tissue ischemia following abdominal aortic vascular surgery (NV17-29701A)

A potential complication of abdominal aortic vascular surgery is an ischemia of intra-abdominal organs. Acute mesenteric ischemia (AMI) is one of the most serious feasible. Ischemia modified albumin (IMA) and circulating mi...

FJ - Chirurgie včetně transplantologie

  • 2017 - 2021
    • •
  • 13 056 tis. Kč
    • •
  • 11 504 tis. Kč
    • •
  • MZ
Project

The influence of systemic hypertension on the development of apoptosis in a temporary focal ischemia in a rat - the correlation with the depth of hypoxia (NR8000)

Already shortlasting brain ischemia carries a risk of apoptosis activation in the ischemic tissue. The finding, whether there is a correlation of the partial pressure of the tissue oxygen with the apoptosis activation, could be used immediat...

FH - Neurologie, neurochirurgie, neurovědy

  • 2004 - 2006
    • •
  • 1 428 tis. Kč
    • •
  • 1 366 tis. Kč
    • •
  • MZ
Project

Focal cerebral ischemia and a long-term reperfusion in rats - the influence of the systemic hypertension on the infarct size (ND5749)

Systemic hypertension used in the period of focal brain ischemia is very likely to decrease its sequelae. We would like to prove the same effect of hypertension also for ischemia with following long-term normotensive reperfusion.......

FH - Neurologie, neurochirurgie, neurovědy

  • 1999 - 2001
    • •
  • 1 248 tis. Kč
    • •
  • 1 223 tis. Kč
    • •
  • MZ
Project

Polydendrocyte function in regeneration after ischemic brain injury - the role of Wnt signaling pathway (GAP303/12/0855)

focal or global cerebral ischemia and to explain the function of Wnt signaling in polydendrocyte proliferation/differentiation during ischemia/reperfusion. In a genetic fate to ischemia will be investigated using transgeni...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
    • •
  • 11 600 tis. Kč
    • •
  • 11 600 tis. Kč
    • •
  • GA ČR
Project

Simulation of alloantigen-independent risk factors for chronic allograft nephropathy in an experimental model and its potential treatment (ND6641)

The aim of the project is to evaluate the effect of ischemia/reperfusion injury in hypertensive transgenic rat. The second aim of the study is to evaluate the effect of renin-angiotensin system inhibition in hypertension accelerated chronic ...

FJ - Chirurgie včetně transplantologie

  • 2001 - 2003
    • •
  • 1 014 tis. Kč
    • •
  • 951 tis. Kč
    • •
  • MZ
Project

Implantation of metal stents in infrapopliteal arteries in patients with critical lower limb ischemia a randomised study "stent vs. PTA" (NR7933)

The aim of the study is to find out if implantation of balloon-expandable or self-expandable stents would favorably influence infrapopliteal arteries patency after percutaneous transluminal angioplasty in patients with critical lower limbs ischem...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2004 - 2007
    • •
  • 4 672 tis. Kč
    • •
  • 4 383 tis. Kč
    • •
  • MZ
Project

Ischemia-reperfusion injury of lungs retrieved from non-heart-beating donors, protection of radical damage (GPP303/10/P343)

is the radical damage during warm ischemia and consecutive reperfusion. Using effect of room-air ventilation during warm ischemia and a protective effect of pre protective effect of ventilation with hypercapnic gas mixture during w...

ED - Fyziologie

  • 2010 - 2012
    • •
  • 1 174 tis. Kč
    • •
  • 1 174 tis. Kč
    • •
  • GA ČR
Project

Laparoscopic diagnostics of the bowel acute ischemia using the fluorescein dye and the ultra-violet light (NR8460)

An acute bowel ischemia still remains representing the disease with a high mortality rate. The delayed diagnostics is considered to be a major cause of the therapeutic drawbacks. Laparoscopic diagnostics of an acute bowel ischemia u...

FJ - Chirurgie včetně transplantologie

  • 2005 - 2007
    • •
  • 1 270 tis. Kč
    • •
  • 1 266 tis. Kč
    • •
  • MZ
Project

Chronic critical limb ischemia - distal revascularization versus distal revascularization and free muscle microsurgical transfer - comparative study (NJ6855)

Multidisciplinary study comparing results of two different treatment modalities for chronic critical limb ischemia. Group A patients treated with isolated distal limb revascularization and group B patients treated with distal limb revascular...

FJ - Chirurgie včetně transplantologie

  • 2001 - 2003
    • •
  • 2 341 tis. Kč
    • •
  • 2 273 tis. Kč
    • •
  • MZ
Project

Mild hypothermia with multimodal monitoring as a perioperative neuroprotective method in neurosurgery (NR8837)

is able to note the episodes of perioperative ischemia. Perioperatively applied hypothermia should protect the brain tissue from irreversible brain ischemia.......

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2008
    • •
  • 2 319 tis. Kč
    • •
  • 2 319 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 106