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142 (0,103s) •

Project

Breast Reconstruction as the Part in the Complex Therapy of the Breast Carcinoma. (IZ2083)

9F - 9

  • 1994 - 1996
    • •
  • 457 tis. Kč
    • •
  • 914 tis. Kč
    • •
  • MZ
Project

Androgenn receptors in hormone dependent carcinomas. (IZ2922)

FD - Onkologie a hematologie

  • 1995 - 1997
    • •
  • 393 tis. Kč
    • •
  • 385 tis. Kč
    • •
  • MZ
Project

Breast conservation in the combination therapy of breast cancer. (IZ1878)

9F - 9

  • 1994 - 1996
    • •
  • 250 tis. Kč
    • •
  • 500 tis. Kč
    • •
  • MZ
Project

Epidemiological study on carcinogenic effects of polychlorinated biphenyls and related compounds. (IZ2366)

9F - 9

  • 1994 - 1996
    • •
  • 160 tis. Kč
    • •
  • 320 tis. Kč
    • •
  • MZ
Project

Identification of genetic factors contributing to hereditary breast cancer development and prognosis (NV15-28830A)

Patients with hereditary breast cancer (BC) represent limited but highly important subgroup of patients suffering from high probability and early onset of BC development, increased risk of disease recurrence and development of other cancers and 50% r...

EB - Genetika a molekulární biologie

  • 2015 - 2018
    • •
  • 8 539 tis. Kč
    • •
  • 8 539 tis. Kč
    • •
  • MZ
Project

Development of novel small molecules anticancer compounds with synthetic lethal effect (NV15-33999A)

The project consists of preclinical development of novel small-molecule selective inhibitor of CHK1 kinase (OH209EN1) with expected effective antitumour activity based on the concept of synthetic lethality. This revolutionary concept in targeted anti...

FD - Onkologie a hematologie

  • 2015 - 2018
    • •
  • 16 815 tis. Kč
    • •
  • 14 821 tis. Kč
    • •
  • MZ
Project

Hereditary cancer predisposition in breast or colorectal cancer patients not indicated for routine genetic testing (NU20-03-00283)

Patients with hereditary cancer syndromes represent a clinically important subgroup of oncology patients. Early identification of pathogenic germline mutations in tens of clinically relevant cancer predisposition genes influences treatment strategies...

Oncology

  • 2020 - 2023
    • •
  • 11 720 tis. Kč
    • •
  • 11 720 tis. Kč
    • •
  • MZ
Project

Xenotransplants of metastatic carcinoma as a tool for preclinical research (NU21-08-00023)

Despite the recent advent of targeted antitumor therapies, metastatic disease remains incurable and accounts for the vast majority of cancer-related deaths. The lack of relevant models, reproducing the pathophysiology of human metastasis limits the p...

Oncology

  • 2021 - 2025
    • •
  • 14 115 tis. Kč
    • •
  • 13 616 tis. Kč
    • •
  • MZ
Project

Significance of special diagnostic methods for the differentiated therapy of pre-tumorous and tumorous brest affections. (IZ2319)

9F - 9

  • 1994 - 1996
    • •
  • 611 tis. Kč
    • •
  • 893 tis. Kč
    • •
  • MZ
Project

Importance of oxysterol signaling for endocrine therapy of breast carcinoma (NV17-28470A)

In the frame of this project, we plan to evaluate importance of genetic and phenotypic markers of oxysterol signaling for endocrine therapy of breast carcinoma. In the long-term perspective, we expect significant socio-economic benefit for both patie...

CE - Biochemie

  • 2017 - 2020
    • •
  • 6 932 tis. Kč
    • •
  • 6 683 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 142