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Projects

7 projects (0,089s) •

Project

The use of genotyping in Streptococcus pneumoniae of serotype 19A to estimate the risk of vaccine replacement. (7F10068)

Respiratory tract infections are the leading causes of childhood mortality in the third world. Pneumococcal pneumonia is among the most serious respiratory tract infections and the pneumococcus is also the leading cause of meningitis, pneumonia and a...

EE - Mikrobiologie, virologie

  • 2010 - 2010
    • •
  • 117 tis. Kč
    • •
  • 117 tis. Kč
    • •
  • MŠMT
Project

Evolution of emergent multidrug resistant Streptococcus pneumoniae 19A serotype in era of pneumococcal vaccination. (NV16-27109A)

Pneumococcus is the major cause of pneumonia, meningitis and bacteremia. A major concern is the occurence of multidrug-resistant (MDR) pneumococci. As the pneumococcal conjugate vaccines target most of MDR serotypes, it was postulated that introducti...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2016 - 2019
    • •
  • 8 566 tis. Kč
    • •
  • 8 071 tis. Kč
    • •
  • MZ
Project

KANVAKOL - vaccine for the therapy of chronic vaginal candidiasis. (IZ2629)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1995 - 1997
    • •
  • 1 235 tis. Kč
    • •
  • 1 235 tis. Kč
    • •
  • MZ
Project

Whole genome sequencing analysis of selected serotypes of Streptococcus pneumoniae causing invasive disease in the Czech Republic (NU22-09-00433)

In a number of countries including the Czech Republic, immunisation programmes involving pneumococcal conjugated vaccines (PCV) have proved highly effective and resulted in reduced incidence and case fatality rate of invasive pneumococcal disease (IP...

Microbiology

  • 2022 - 2025
    • •
  • 7 383 tis. Kč
    • •
  • 6 757 tis. Kč
    • •
  • MZ
Project

Immunosuppressive action of the whooping cough agent and new vaccination tools for prevention of pertussis (NV16-28126A)

Pertussis or whooping cough is a life threatening infectious disease that is now spreading in the highly vaccinated populations of the most developed countries. This is largely due to use of safe but less efficient acellular pertussis vaccines that w...

EE - Mikrobiologie, virologie

  • 2016 - 2019
    • •
  • 9 920 tis. Kč
    • •
  • 9 920 tis. Kč
    • •
  • MZ
Project

Construction of recombinant mimotopes for induction of neutralizing antibodies against HIV-1 gp120 glycoprotein using high-affinity binders approach (NV15-32198A)

Development of vaccine preventing HIV-1 infection is hindered by high variability of envelope glycoprotein (Env), known target for neutralizing antibodies. Identification of several monoclonal antibodies neutralizing broad range of HIV-1 variants (b...

EC - Imunologie

  • 2015 - 2018
    • •
  • 6 200 tis. Kč
    • •
  • 6 200 tis. Kč
    • •
  • MZ
Project

High-affinity protein binders of hepatitis C virus broadly-neutralizing antibodies as a base for preventative vaccine (NU23-05-00203)

More than 130 million people worldwide are infected with hepatitis C virus (HCV). Highly effective direct-acting antivirals are available to only limited number of infected individuals and thus the risk of developing chronic HCV infection-associated ...

Immunology

  • 2023 - 2026
    • •
  • 13 783 tis. Kč
    • •
  • 13 783 tis. Kč
    • •
  • MZ
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