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Projects

897 projects (0,103s)

Project

Engineering radionuclide - labeled antibodies (OE 210)

production of prototype radioimunological agent based on protein-engineered antibody with required combination of desirable properties...

EC - Imunologie

  • 2006 - 2009
  • 18 186 tis. Kč
  • 9 093 tis. Kč
  • MŠMT
Project

Metal-nanopartcials based multilabeling for bioimaging (GA17-12774S)

on the interaction of antibody labelled with metal-based nanoparticle with its antigen. The metal coupled plasma mass spectrometry (LA-ICP-MS). The labelling of antibodies will be done by metallic nanoparticles (r...

CB - Analytická chemie, separace

  • 2017 - 2021
  • 6 136 tis. Kč
  • 6 055 tis. Kč
  • GA ČR
Project

Labelling of recombinant antibody fragments with use of microfluidic systems (TA02010797)

Project aims at design, development and construction of two unique devices and offer of one commercially available service. The first device is an automated microfluidic system AMfS, primarilly for radioactive labelling of antibodies

CH - Jaderná a kvantová chemie, fotochemie

  • 2012 - 2014
  • 25 660 tis. Kč
  • 15 745 tis. Kč
  • TA ČR
Project

Labelling of monoclonal antibodies with At-211 for targeted cancer therapy (KJB4048302)

of the product, and the investigation of several labelling methods for astatination of a model monoclonal antibody and their comparison with respect to the labelling yield radioimmunoconjugates.Obtained knowledge will be a...

CH - Jaderná a kvantová chemie, fotochemie

  • 2003 - 2005
  • 1 656 tis. Kč
  • 1 336 tis. Kč
  • AV ČR
Project

Preparation of new radiopharmaceuticals based on monoclonal and recombinant antibodies and peptides labelled by alpha and beta radionuclides (IBS1048301)

A. Choice of approppriate monoclonal antibodies (MABs) and their scFv fragments. The following MABs and their fragments will be examined in the first step: TU-20, an antibody against neuron-specific tubuline, MEM-97, an antibody...

CH - Jaderná a kvantová chemie, fotochemie

  • 2003 - 2005
  • 7 375 tis. Kč
  • 3 731 tis. Kč
  • AV ČR
Project

Innovation and automation of the manufacture technology for fluorescently labeled monoclonal antibodies (FX03030118)

of monoclonal antibodies labeled with specific organic fluorescent molecules. Fluorescence-labeled antibodies are the basis for the group of IVD medical devices in the field of the critical step of monoclonal ...

Cell biology

  • 2021 - 2024
  • 21 686 tis. Kč
  • 10 646 tis. Kč
  • MPO
Project

New generation of reagents for diagnostic radioimmunoassays_2 (OE67/2)

Aim of the project is to develop novel derivates of monoclonal antibodies as diagnostic RIA reagents. Single-chain Fv fragments (scFvs) produced in E.coli will provide the access to their engineering towards better labelling and sta...

FP - Ostatní lékařské obory

  • 2000 - 2002
  • 4 088 tis. Kč
  • 1 838 tis. Kč
  • MŠMT
Project

New generation of reagents for diagnostic radioimmunoassays_1 (OE67/1)

Aim of the project is todevelop novel derivates of monoclonal antibodies as diagnostic RIA reagents. Single-chain Fv fragments (scFvs) produced in E.coli will provide the access to their engineering towards better labelling and stab...

FP - Ostatní lékařské obory

  • 2000 - 2002
  • 5 738 tis. Kč
  • 2 338 tis. Kč
  • MŠMT
Project

Primary ciliary aplasia (OK 266)

of mitotic spindles. Prepartion, purification and labelling of antibodies for coIsolation of gamma-tubulins from RBL cells and from brain tissue on preparative columns with bound TU-31 antibody. Electrophoretic analysis of...

EI - Biotechnologie a bionika

  • 1997 - 1999
  • 3 780 tis. Kč
  • 2 080 tis. Kč
  • MŠMT
Project

Development of terbium-161-labelled biomolecules as theranostic tools in nuclear medicine (NU23-08-00214)

biomolecules. The project involved several novel anticancer monoclonal antibodies targeting various receptors expressed in cancer tissues. The antibodies will be labelled either will be performed. The forms of antibodi...

Pharmacology and pharmacy

  • 2023 - 2026
  • 12 705 tis. Kč
  • 12 705 tis. Kč
  • MZ
  • 1 - 10 out of 897