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467 (0,11s)

Project

In-silico Workflow for Lipid-Mediated Active Pharmaceutical Ingredients Delivery Systems (GA25-18467S)

Lipid-mediated active pharmaceutical ingredients (APIs) delivery systems have enormous potential for the treatment of cancer or rare diseases. Lipid nanocarriers simulations of lipid-mediated API delivery systems t...

Physical chemistry

  • 2025 - 2027
  • 5 109 tis. Kč
  • 5 109 tis. Kč
  • GA ČR
Project

Lipid membrane models – a new tool for studying pathophysiology of skin diseases at a molecular level (GA13-23891S)

delivered (pseudo)ceramides using lipid nanocarriers. This project will be the first membrane models of the lipid skin barrier in atopic dermatitis and other skin diseases to gain a detailed insight into the role of li...

FR - Farmakologie a lékárnická chemie

  • 2013 - 2017
  • 9 734 tis. Kč
  • 9 734 tis. Kč
  • GA ČR
Project

Nanopesticides in the environment – understanding their fate, bioavailability, effects and risks in soil and water (GA18-19324S)

particle chemistry, bound vs free pesticides, and loaded vs free nanocarriers...

Environmental sciences (social aspects to be 5.7)

  • 2018 - 2022
  • 6 338 tis. Kč
  • 5 992 tis. Kč
  • GA ČR
Project

Hybrid magnetic "stealth" nano-structures for the targeted and controlled release of doxorubicin (7AMB12GR026)

The present research proposal aims to advance a step further the design and performance of physically targeted drug nanocarriers for cationic drugs such as doxorubicin - a potent drug but with serious side effects. Therefore, new multifuncti...

CA - Anorganická chemie

  • 2012 - 2013
  • 114 tis. Kč
  • 114 tis. Kč
  • MŠMT
Project

Novel Insights into the Nanostructure of the Skin Lipid Barrier by Biophysical Methods (GF22-20839K)

The skin lipid barrier, an extracellular ceramide-based multilamellar lipid mechanisms and conditions of lipid assembly into a functional barrier and the exact of these lipids´ nanoscopic architecture, probe the ro...

Biophysics

  • 2022 - 2025
  • 7 911 tis. Kč
  • 7 911 tis. Kč
  • GA ČR
Project

A robust reactive-oxygen-species scavenging nanomedicine for antioxidant therapy (GA25-15996S)

-responsive nanocarrier to deliver the antioxidant nanozymes at targeted sites to regulate nanocarriers in vitro regarding their cytotoxicity, cellular uptake, stimuli-responsive......

Health-related biotechnology

  • 2025 - 2027
  • 12 933 tis. Kč
  • 12 864 tis. Kč
  • GA ČR
Project

International mobility of researchers - MSCA-IF IV (Institute of Microbiology of the CAS, v. v. i.) (EF20_079/0017812)

to commercially viable, stress-free accumulation of lipids. The SingleCellN2fix project of anticancer drug based on gold nanocarriers. The planned mobilities for 24 months should......

Microbiology

  • 2020 - 2023
  • 8 120 tis. Kč
  • 1 551 tis. Kč
  • MŠMT
Project

The role of lipids and lipid-metabolizing enzymes in plant autophagy (LTC17084)

The main objective of the project is elucidation of involvement of lipids and lipid-metabolizing enzymes in plant autophagy. In order to achieve the main of lipid metabolism knockout mutants with altered autophagy, verifica...

ED - Fyziologie

  • 2017 - 2020
  • 3 688 tis. Kč
  • 3 688 tis. Kč
  • MŠMT
Project

*New procedures of the lipid micro- and nanodispersion systems formulation as the transport systems of pharmacological active substances (2A-1TP1/015)

*The aim of the project is to indroduce new technological procedures of lipid emulsions and solid lipid nanodispersion formulation and to utilize them as carriers of drugs mainly for per oral and topical administrations.......

JP - Průmyslové procesy a zpracování

  • 2006 - 2011
  • 15 011 tis. Kč
  • 9 201 tis. Kč
  • MPO
Project

How lipid asymmetry influences membrane protein function (GF25-19982L)

, characterized by distinct lipid compositions in their two leaflets, most studies use, elucidating the structural and dynamical properties of lipids in asymmetric membranes and their interactions with integral membrane proteins, fo...

Biophysics

  • 2025 - 2027
  • 5 318 tis. Kč
  • 5 318 tis. Kč
  • GA ČR
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