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454 (0,125s) •

Project

Novel Insights into the Nanostructure of the Skin Lipid Barrier by Biophysical Methods (GF22-20839K)

The skin lipid barrier, an extracellular ceramide-based multilamellar lipid mechanisms and conditions of lipid assembly into a functional barrier and the exact of these lipids´ nanoscopic architecture, probe the ro...

Biophysics

  • 2022 - 2025
    • •
  • 7 911 tis. Kč
    • •
  • 7 911 tis. Kč
    • •
  • GA ČR
Project

The role of lipids and lipid-metabolizing enzymes in plant autophagy (LTC17084)

The main objective of the project is elucidation of involvement of lipids and lipid-metabolizing enzymes in plant autophagy. In order to achieve the main of lipid metabolism knockout mutants with altered autophagy, verifica...

ED - Fyziologie

  • 2017 - 2020
    • •
  • 3 688 tis. Kč
    • •
  • 3 688 tis. Kč
    • •
  • MŠMT
Project

*New procedures of the lipid micro- and nanodispersion systems formulation as the transport systems of pharmacological active substances (2A-1TP1/015)

*The aim of the project is to indroduce new technological procedures of lipid emulsions and solid lipid nanodispersion formulation and to utilize them as carriers of drugs mainly for per oral and topical administrations.......

JP - Průmyslové procesy a zpracování

  • 2006 - 2011
    • •
  • 15 011 tis. Kč
    • •
  • 9 201 tis. Kč
    • •
  • MPO
Project

How lipid asymmetry influences membrane protein function (GF25-19982L)

, characterized by distinct lipid compositions in their two leaflets, most studies use, elucidating the structural and dynamical properties of lipids in asymmetric membranes and their interactions with integral membrane proteins, fo...

Biophysics

  • 2025 - 2027
    • •
  • 5 318 tis. Kč
    • •
  • 5 318 tis. Kč
    • •
  • GA ČR
Project

Understanding the mechanisms of epidermal lipid barrier formation, damage and repair implications for skin diseases (GA25-17203S)

mechanisms of the formation of this hydrophobic, ceramide-rich lipid mixture teams, combining methods of lipid synthesis, analysis and biophysics of formation of human barrier lipid assemblies and the conditions for their ...

Pharmacology and pharmacy

  • 2025 - 2027
    • •
  • 11 956 tis. Kč
    • •
  • 11 704 tis. Kč
    • •
  • GA ČR
Project

Structural and functional analysis of regulation of the lipid-transport protein ORP8 (GF21-27735K)

Lipids transport between various membranous intracellular organelles family specialized in transporting lipids. Oxysterol-binding protein (OSBP)-related proteins (ORPs) mediate lipid transfer at the membrane contact sites s...

Biochemistry and molecular biology

  • 2021 - 2023
    • •
  • 4 220 tis. Kč
    • •
  • 3 260 tis. Kč
    • •
  • GA ČR
Project

Lipids of bumblebees and their role in the biosynthesis of pheromonal components (IAA4055403)

Storage, mobilisation, transport, and metabolism of lipids in different components of the male marking pheromone. Composition of lipids in different species will be determined. Storage form of lipids in the fat body [triacy...

CC - Organická chemie

  • 2004 - 2008
    • •
  • 2 650 tis. Kč
    • •
  • 2 650 tis. Kč
    • •
  • AV ČR
Project

Pleiotropic effects of hypolipidemics (1P05OC065)

study of selected physiologically important pathways of regulation of lipid metabolism (dietary and endogenic) in organism...

FR - Farmakologie a lékárnická chemie

  • 2005 - 2008
    • •
  • 3 891 tis. Kč
    • •
  • 2 526 tis. Kč
    • •
  • MŠMT
Project

Cellular lipidome as diagnostic, predictive and therapeutic factor in colon cancer (NV15-30585A)

of cellular lipids and/or their metabolism, and it is associated with further modulations of cell behaviour by both dietary and endogenous lipid compounds. However, complex of these lipid molecules and currently used tumou...

FD - Onkologie a hematologie

  • 2015 - 2020
    • •
  • 14 729 tis. Kč
    • •
  • 14 647 tis. Kč
    • •
  • MZ
Project

Role of lipids in defense reaction of plants (ME 598)

The project is oriented to elicitins, proteinaceous elicitors from Phytophthora sp. that are similar to LTP, plant lipid transfer proteins. Our previous work has and in,the interaction with lipids. The principle method of the projec...

CE - Biochemie

  • 2002 - 2003
    • •
  • 1 359 tis. Kč
    • •
  • 403 tis. Kč
    • •
  • MŠMT
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