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576 (0,099s) •

Project

Transcription factor MITF in melanoma and transcription factor HASH1 in small cell lung carcinoma use in diagnosis and prognosis and their role in pathogenesis. (NR8026)

We propose to use multiple independent molecular approaches to elucidate the importance of the transcription factor MITF in the pathogenesis of human melanoma and the role of transcription factor HASH1 in small cell lung carcinoma. ...

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 4 747 tis. Kč
    • •
  • 4 661 tis. Kč
    • •
  • MZ
Project

Study of expression and activation of apoptogenic caspases and of levels of their inhibitors in non-small cell lung carcinoma (NC6610)

Study of expression and activation of apoptogennic caspases and of levels of their inhibitors XIAP and survivin in human non-small cell lung carcinoma with the aim to evaluate their correlation with progression of this cancer diseas...

FD - Onkologie a hematologie

  • 2001 - 2003
    • •
  • 3 500 tis. Kč
    • •
  • 3 470 tis. Kč
    • •
  • MZ
Project

Study of apoptosis in human nonsmall cell lung cancer (NC4963)

Study of apoptosis induction in human nonsmall cell lung cancer cell lines and mapping some apoptogenic factors in nonsmall cell lung carcinomas.......

FD - Onkologie a hematologie

  • 1998 - 2000
    • •
  • 4 738 tis. Kč
    • •
  • 4 245 tis. Kč
    • •
  • MZ
Project

Growth features of the lung cancers in relation to their typing. (IZ4187)

prognostic evaluation of lung carcinomas would be more reliable with immunohistochemical analysis of the growth activity,suppression of growth and metastases and readiness for apoptosis in cancer cells.......

FP - Ostatní lékařské obory

  • 1997 - 1999
    • •
  • 435 tis. Kč
    • •
  • 435 tis. Kč
    • •
  • MZ
Project

Exposure to Arsenic and Cancer Risk in Central and East Europe (OK 406)

Form up malignity database registered in 15 years epidemiological study with special respect to skin carcinomas, lung carcinomas, kidney carcinomas and urine bladder carcinomas. Completed of biological mon...

FD - Onkologie a hematologie

  • 1998 - 2000
    • •
  • 1 156 tis. Kč
    • •
  • 500 tis. Kč
    • •
  • MŠMT
Project

Transcription of differentiation- specific genes and expression of neuroendocrine markers in small- cell lung carcinoma and some neuroectodermal tumors. (IZ952)

9F - 9

  • 1992 - 1995
    • •
  • 750 tis. Kč
    • •
  • 1 500 tis. Kč
    • •
  • MZ
Project

Gemcitabine plus cisplatin versus gemcitabine plus carboplatin in non-small cell lung cancer stage IIIB and IV. A randomized study. (NC6070)

A randomized multi cencer clinical study comparing two chemothrapeutic regimens cisplation+gemcitabine versus carboplatin+gemcitabine in locoregionally advanced and metastatic non-small cell lung cancer......

FD - Onkologie a hematologie

  • 2000 - 2002
    • •
  • 257 tis. Kč
    • •
  • 257 tis. Kč
    • •
  • MZ
Project

Assessment of biological activity of a tumour for prognosis and optimizing of a non- smal- cell lung carcinoma (NSCLC) therapy (NR9343)

1. Systematic observation of levels of invasiveness parameters and of NSCLC tumour metastasizing parameters in a tumorous tissue, and in the part of NSCLC patient ´s lung not affected by the tumour. 2. Comparison of commonly used NSCLC onco-...

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 3 157 tis. Kč
    • •
  • 3 151 tis. Kč
    • •
  • MZ
Project

Diagnostics of cancer with Next Generation Sequencing (TA04010838)

Main focus of project is development and verification of kit for preparation of genetic libary for next generation sequencing (NGS), which allows detail genetic diagnostics of colorectal cancer (CRC) and NSCLC (Non Small Cell Lung Carcin...

EB - Genetika a molekulární biologie

  • 2014 - 2017
    • •
  • 19 053 tis. Kč
    • •
  • 12 356 tis. Kč
    • •
  • TA ČR
Project

Dysfunction of the apoptosome pathway in non-small cell lung cancer (NS9715)

The project is aimed at the study of molecular mechanisms underlying apoptosome pathway dysfunction in non-small cell lung carcinoma (NSCLC) cells and tissues, with using the methods of derepression of apoptosome apparatus activatio...

FD - Onkologie a hematologie

  • 2008 - 2011
    • •
  • 5 508 tis. Kč
    • •
  • 5 508 tis. Kč
    • •
  • MZ
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