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7 129 (0,087s) •

Project

Influence of pulmonary contusion on the prognosis of children with serious injury. Effect of the mechanical ventilation. (ND5869)

aimed at duration and mode of mechanical ventilation. Analysis of a group of children after prolonged mechanical ventilation without thoracic injury in a 10 year period. Comparison of lung functions in the two groups of pa...

FJ - Chirurgie včetně transplantologie

  • 2000 - 2002
    • •
  • 1 354 tis. Kč
    • •
  • 1 354 tis. Kč
    • •
  • MZ
Project

Pulmonary stress and regeneration (GA23-06675S)

Physiological molecular response of lung cells to factors evoking cell stress and tissue damage is critical for full regeneration of lung parenchyma. The abnormal cell stress response can deteriorate the fine architecture of lun...

Cell biology

  • 2023 - 2025
    • •
  • 6 996 tis. Kč
    • •
  • 6 935 tis. Kč
    • •
  • GA ČR
Project

Role of free radicals in the regulation of lung inflammation induced by acute and chronic exposure to endotoxin (GA524/06/1197)

mechanism contributing to the pathology of lung inflammation induced by chronic LPS dust induced chronic lung inflammations. Reactive oxygen and nitrogen species (RONS injury, in the mechanism of LPS mediated toxi...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2006 - 2008
    • •
  • 3 101 tis. Kč
    • •
  • 3 101 tis. Kč
    • •
  • GA ČR
Project

Calcium release from the sarcoplasmic reticulum in the regulation of the pulmonary circulation during hypoxia (GA305/00/1432)

by a local vasoconstriction in the hypoventilated (and therefore hypoxic) lung areas, which diverts blood flow towards better ventilated lung regions. The mechanismSmall lung regions may be insufficiently ventilat...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2000 - 2002
    • •
  • 2 656 tis. Kč
    • •
  • 2 656 tis. Kč
    • •
  • GA ČR
Project

The effect of metal nanoparticles on lung tissues and cell processes contributing to their efflux from these tissues (GA24-10051S)

of mechanisms that contribute to nanoparticle clearance from lung tissues will open new (lead and cadmium) present in urban aerosol on lungs, which is a typical organ and cadmium nanoparticles effects on individual lun...

Toxicology

  • 2024 - 2026
    • •
  • 11 601 tis. Kč
    • •
  • 11 582 tis. Kč
    • •
  • GA ČR
Project

Principles and noninvasive real-time measurements of pulmonary vascular mechanics and ventilation-perfusion matching (GA22-34020S)

Better understanding and real-time monitoring of pulmonary vascular mechanics and mechanisms underlying regional ventilation and perfusion (V/Q) mismatching is needed. In heterogeneously ventilated lungs vascular mechan...

Physiology (including cytology)

  • 2022 - 2024
    • •
  • 12 333 tis. Kč
    • •
  • 12 333 tis. Kč
    • •
  • GA ČR
Project

Vascular reactivity in pulmonary hypertension (GA13-01710S)

in neonatal period. The mechanisms determining the pulmonary vascular reactivity in lungChronic and intermittent lung hypoxia causes hypoxic pulmonary hypertension and fibrotization) of pulmonary preaveolar blood vessels. ...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2013 - 2017
    • •
  • 8 709 tis. Kč
    • •
  • 8 709 tis. Kč
    • •
  • GA ČR
Project

Mechanisms of early and late changes of pulmonary blood vessels after the lung tissue injury (GA305/96/0068)

ED - Fyziologie

  • 1996 - 1996
    • •
  • 0 tis. Kč
    • •
  • 2 055 tis. Kč
    • •
  • GA ČR
Project

Roles of the rhomboid intramembrane protease RHBDL2 in lung epithelial homeostasis and pathology of idiopathic pulmonary fibrosis (GA21-24456S)

molecular mechanisms influencing lung epithelial homeostasis, with potential in epithelial cells, and hypothesise that this underlies its influence on lung fibrosis. Now, using primary lung epithelial cells, our R...

Cell biology

  • 2021 - 2023
    • •
  • 9 840 tis. Kč
    • •
  • 9 345 tis. Kč
    • •
  • GA ČR
Project

Dysfunction of the apoptosome pathway in non-small cell lung cancer (NS9715)

The project is aimed at the study of molecular mechanisms underlying apoptosome pathway dysfunction in non-small cell lung carcinoma (NSCLC) cells and tissues, with using the methods of derepression of apoptosome apparatus activatio...

FD - Onkologie a hematologie

  • 2008 - 2011
    • •
  • 5 508 tis. Kč
    • •
  • 5 508 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 7 129