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292 (0,077s) •

Project

New methods of biodosimetry and diagnostics in irradiated soldiers (OBUKHK2005001)

of 0,2-3 Gy of ionizing radiation, using human lymphocytes and model lymphocyte cell) and cells in G0 phase of cell cycle (peripheral lymphocytes). We will study apoptosis induction at lymphocytes subpopulations, ...

CE - Biochemie

  • 2005 - 2007
    • •
  • 2 477 tis. Kč
    • •
  • 2 477 tis. Kč
    • •
  • MO
Project

Detection of specific cellular immune response to Helicobacter pylori antigens in patients with autoimmune thyroiditis (NR9414)

Detection of lymphocyte memory response to Helicobacter pylori (Hp) antigens. Senzibilization of lymphocytes and evaluation of change of memory response by modified lymphocyte transformation test after antibiotic Hp eradica...

EE - Mikrobiologie, virologie

  • 2007 - 2010
    • •
  • 4 384 tis. Kč
    • •
  • 4 296 tis. Kč
    • •
  • MZ
Project

Apoptosis of peripheral T-lymphocytes in heart transplant recipients (NI6338)

In the project submitted we plan to assess apoptosis of peripheral T-lymphocytes in relation to combined immunosuppresive therapies and acute rejection episode treatment in heart transplant recipients.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2000 - 2002
    • •
  • 692 tis. Kč
    • •
  • 662 tis. Kč
    • •
  • MZ
Project

Influence of some lymphocyte subpopulations and markers of thrombocyte activation to the clinical progress of preeclampsia (NR8906)

The objective of this project is to determine expression of some subpopulations of lymphocytes which influence the damage of endothelium and markers of thrombocyte activation and their influance om the degree of preeclampsia.......

FK - Gynekologie a porodnictví

  • 2006 - 2008
    • •
  • 1 804 tis. Kč
    • •
  • 1 703 tis. Kč
    • •
  • MZ
Project

Identification of novel molecular pathways involved in the process of B-cell allelic exclusion; chronic lymphocytic leukemia as the model system (NS9652)

of B-lymphocytes. The process is strictly controlled and aberrant B-lymphocytes, expressing two IgVH alleles, are eliminated. Chronic lymphocytic leukemia (CLL) is a clonal disorder of B-lymphocytes. In 5-8% of ca...

FD - Onkologie a hematologie

  • 2008 - 2011
    • •
  • 8 112 tis. Kč
    • •
  • 8 082 tis. Kč
    • •
  • MZ
Project

Antenatal identification of CD marks of fetal lymphocytes from cordocent esis (study of imunotolerancy mother and foetus (IZ3201)

9F - 9

  • 1995 - 1996
    • •
  • 253 tis. Kč
    • •
  • 253 tis. Kč
    • •
  • MZ
Project

Activation of HIV-Specific CD8+ T Lymphocytes by IL-2 and Histamine Possible Use in Therapy? (NR9032)

Based on the results of the study with patients with hepatitis C and some oncologic diseases we will study in vitro activation of HIV-specific CD8+ T lymphocytes and IFN-gammaHistamine induces activation of cytotoxic CD8+ T Lymphocytes

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2006 - 2008
    • •
  • 2 200 tis. Kč
    • •
  • 2 200 tis. Kč
    • •
  • MZ
Project

A role of B lymphocytes in immune reactions after kidney transplantation (NT14102)

In this project, we will investigate the role of B-lymphocytes phentotypes and their transcripts in peripheral blood and the donor specific antibodies in alloimune response in the cohort of kidney transplant recipients, and in experimental m...

FJ - Chirurgie včetně transplantologie

  • 2013 - 2015
    • •
  • 7 609 tis. Kč
    • •
  • 7 609 tis. Kč
    • •
  • MZ
Project

Deciphering molecular mechanisms that drive lymphocyte morphological polarization and migration under mechanical confinement. (GJ20-24603Y)

An efficient adaptive immune response requires lymphocytes to be at the right place at the right time and depends upon lymphocytes migration and correct positioning in lymphoid tissues. According to the current paradigm, lymphoc...

Cell biology

  • 2020 - 2022
    • •
  • 7 897 tis. Kč
    • •
  • 7 897 tis. Kč
    • •
  • GA ČR
Project

Use of lymphocyte mitochondria for detection and prospective analysis of mitochondrial diseases. (NT12370)

To adapt and optimize modern biochemical and functional methods for analysis of mitochondrial energetic metabolism in blood lymphocytes: (i) To use highly sensitive oxygraphy of permeabilized lymphocytes, luciferase analysis of ATP ...

FG - Pediatrie

  • 2011 - 2015
    • •
  • 8 773 tis. Kč
    • •
  • 8 773 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 292