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7 (0,075s) •

Project

Molecular cytogenetic analysis of complex chromosomal aberrations in bone marrow cells of patients with myelodysplastic syndrome (MDS) and/or acute myeloid leukemia (AML) and AND its contribution for prognosis. (NR9227)

Molecular cytogenetic analysis of complex chromosomal aberrations in patients with MDS and AML. Identification of chromosomes and/or chromosomal regions involved in complex karyotypes. Evaluation of the impact of complex rearrangements on prognosis o...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 3 054 tis. Kč
    • •
  • 2 953 tis. Kč
    • •
  • MZ
Project

Genomic instability of leukemic cells at chromosomal level (GA301/04/0407)

in situ hybridization (FISH), interphase FISH (I FISH), multicolor FISH (mFISH), multicolor banding (mBAND) and comparative genomic hybridization (CHG) was found......

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 2 710 tis. Kč
    • •
  • 2 710 tis. Kč
    • •
  • GA ČR
Project

The usage of FISH metods (LSI and MFISH)and echocardiography for the complex diagnostic systém of congenital heart diseases. (NM6080)

The implementation of FISH-LSI and MFISH will allow to perform rapid investigation of karyotype in a pre - and postnatal patients with echographycaly diagnose (or nonexistesion) of microdeletion. MFISH-Automatic image acquisition,me...

FG - Pediatrie

  • 2000 - 2002
    • •
  • 2 955 tis. Kč
    • •
  • 2 955 tis. Kč
    • •
  • MZ
Project

Instability of the genome of bone marrow cells of patients with AML and MDS. (OC10043)

methods routinely used in our Center of Oncocytogenetics (FISH, I-FISH. mFISH, mBAND...

EB - Genetika a molekulární biologie

  • 2010 - 2012
    • •
  • 2 100 tis. Kč
    • •
  • 2 100 tis. Kč
    • •
  • MŠMT
Project

Anylysis of inborn and acquired chromosomal changes in human somatic and malignant cells by multicolor fluorescence in situ hybridization (mFSH) (GA301/01/0200)

The aim of the study is by the means of mFISH: - To introduce the multicolor fluorescence in situ hybridisation (mFISH) for analysis of small interchromosomal congenital changes in patients with various genetic syndromes (Fanconi an...

FP - Ostatní lékařské obory

  • 2001 - 2003
    • •
  • 2 110 tis. Kč
    • •
  • 1 950 tis. Kč
    • •
  • GA ČR
Project

Mapping of the breakpoints of deletions and cryptic aberrations of chromosomes 3 and 7 in hematological malignancies using molecular cytogenetic techniques (NR7995)

Mapping of the breakpoints on chromosomes 3 and 7 in bone marrow cells of patients with myeloid and lymphoid malignancies. Evaluation of significance of different breakpoints for the prognosis of the patients.......

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 3 807 tis. Kč
    • •
  • 3 614 tis. Kč
    • •
  • MZ
Project

Optimising molecular cytogenetic and molecular genetic diagnostics of chromosomal aberrations in patients with mental retardation (NR9457)

The use of FISH with locus-specific probes, mFISH, microarray CGH and MLPA in the diagnostics of idiopathic mental retardations and autism with mental retardation. Elaboration of an algorithm for patient selection for the analysis by molecul...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 7 098 tis. Kč
    • •
  • 7 032 tis. Kč
    • •
  • MZ
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