All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Filters

975 (0,173s)

Project

Regulation of translation initiation during meiotic maturation of pig oocytes by protein factors associated with mRNA 3'-end (GA524/07/1087)

Translation initiation is the rate-limiting step in the regulation of translation and it is influenced by cis-acting elements located primarily in the mRNA 5´ and 3´ untranslated regions - UTRs. As the factors regulating th...

ED - Fyziologie

  • 2007 - 2009
  • 2 335 tis. Kč
  • 2 335 tis. Kč
  • GA ČR
Project

Translation regulation in plant dormant reproduction units - pollen and seeds (GA21-15856S)

The phenomenon of translational regulation and mRNA storage has been studied - share mRNA storage mechanism that is highly similar if not even the same. In both structures, translationally silent, stored mRNA was i...

Plant sciences, botany

  • 2021 - 2023
  • 11 994 tis. Kč
  • 11 994 tis. Kč
  • GA ČR
Project

Characterization of the ribosome translating pre-spliced mRNAs for the synthesis of antigenic peptide substrates for the MHC-I pathway (GA23-06884S)

that MHC-I APs are produced by a non-canonical mRNA translation event that is distinct from the conventional translation system producing full-length proteins. Using data show that translation of pre-spliced m...

Immunology

  • 2023 - 2025
  • 10 603 tis. Kč
  • 10 357 tis. Kč
  • GA ČR
Project

The role of 5' mRNA untranslated regions in a control of eukaryotic gene expression (GA204/03/1487)

In our proposed project we are focused mainly on cap-independent translation initiation. The major objective is to find new cellular mRNAs translated by cap in mRNAdecay. Obtained information will be used for screening for ...

EB - Genetika a molekulární biologie

  • 2003 - 2005
  • 4 958 tis. Kč
  • 2 970 tis. Kč
  • GA ČR
Project

Role of cytoskeleton in dynamics of ntp303 mRNA distribution, storage and activation in the process of tobacco pollen maturation and tube growth (IAA5038207)

Tobacco pollen specific ntp303 gene represents a natural model of translational from stored mRNAs synthesized during pollen maturation. Our pilot study proved binding protein regulating its translatability (GA AV A5038801 g...

EB - Genetika a molekulární biologie

  • 2002 - 2005
  • 10 105 tis. Kč
  • 3 254 tis. Kč
  • AV ČR
Project

Global and transcript-specific analysis of translational control in disease. (GX19-25821X)

, it can be achieved on the level of translation of genetic information from mRNA into protein. Evidence for the importance of proper translational control is overwhelming, as even a small disturbance in timing or fidelity ...

Biochemistry and molecular biology

  • 2019 - 2023
  • 45 840 tis. Kč
  • 45 840 tis. Kč
  • GA ČR
Project

Targeting the IRES-driven translation mechanism as a new strategy to prevent cancer development (GCP305/10/J026)

-state levels of mRNA and the expression levels of proteins encoded by those mRNAs translational regulation. Two kinds of mechanisms, cap-dependent scanning and internal of translation. Translation initiat...

EB - Genetika a molekulární biologie

  • 2010 - 2014
  • 4 336 tis. Kč
  • 4 336 tis. Kč
  • GA ČR
Project

Identification of proteins involved in the posttranscriptional regulation of expression of tobacco (Nicotiana tabacum) male gametophyte-specific genes (IAA5038801)

stopped, intensive translational activity is still growth-limiting, based on mRNA mRNP particles and to analyze the proteins that are engaged in mRNA repression. The Ntp303 gene, transcribed and stored in immature bovacco ...

EB - Genetika a molekulární biologie

  • 1998 - 2000
  • 4 671 tis. Kč
  • 1 702 tis. Kč
  • AV ČR
Project

Depicting a functional model of NTP303 mRNA translational repression during tobacco pollen maturation (GPP501/11/P321)

) imposed to repress the translation of NTP303 mRNA during pollen maturation. Our NTP303 mRNA translation and to demonstrate their function. Simultaneously, (ii) we, however, the encoded mRNAs are translat...

ED - Fyziologie

  • 2011 - 2013
  • 3 034 tis. Kč
  • 3 034 tis. Kč
  • GA ČR
Project

Regulation of translation during plant stress response (GA25-16195S)

and store the translational machinery and mRNAs, remodeling the cellular program towards this response. One of the key regulators of eukaryotic proteosynthesis is the translation hypothesize that these isoforms are associa...

Biochemistry and molecular biology

  • 2025 - 2027
  • 7 766 tis. Kč
  • 7 766 tis. Kč
  • GA ČR
  • 1 - 10 out of 975