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3 574 (0,154s) •

Project

Regulation of gene expression by a new mRNA-binding factor (GA16-10930S)

Recent studies have shown that more mRNA-binding proteins (mRBP) exist than previously thought, particularly among proteins without a canonical RNA-binding motif. By characterizing CDK- mRNA-b...

EB - Genetika a molekulární biologie

  • 2016 - 2020
    • •
  • 9 396 tis. Kč
    • •
  • 9 396 tis. Kč
    • •
  • GA ČR
Project

Regulation of translation initiation during meiotic maturation of pig oocytes by protein factors associated with mRNA 3'-end (GA524/07/1087)

´ and 3´ untranslated regions - UTRs. As the factors regulating the mRNA binding to the ribosomes(i.e. factors acting at the mRNA 5'-end, the cap-binding protein complex eIF4F with the mRNA 3'-end...

ED - Fyziologie

  • 2007 - 2009
    • •
  • 2 335 tis. Kč
    • •
  • 2 335 tis. Kč
    • •
  • GA ČR
Project

Role of cytoskeleton in dynamics of ntp303 mRNA distribution, storage and activation in the process of tobacco pollen maturation and tube growth (IAA5038207)

between ntp303 mRNA, RNA-binding proteins and cytoskeleton. resistant particles, and a 30 kDa protein was identified as a candidate for a ntp303mRNA binding protein regulating its translatability...

EB - Genetika a molekulární biologie

  • 2002 - 2005
    • •
  • 10 105 tis. Kč
    • •
  • 3 254 tis. Kč
    • •
  • AV ČR
Project

A novel protein of mineralized matrix with cell binding domains (IZ3735)

FP - Ostatní lékařské obory

  • 1996 - 1998
    • •
  • 1 772 tis. Kč
    • •
  • 1 172 tis. Kč
    • •
  • MZ
Project

The expression of DMPK mRNA and DMPK protein in normal human tissues and the presence of nuclear foci containing (CUG)n and (CCUG)n expanded transcripts of DMPK in tissues of patients with myotonic (NS9877)

In order to better characterize the role of DMPK loss and the effects of CUG repeat expression in the development of DM pathology, we plan (1) to establish the identity of normal tissues and cell types in which the DMPK protein and the DMPK ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2008 - 2011
    • •
  • 1 962 tis. Kč
    • •
  • 1 962 tis. Kč
    • •
  • MZ
Project

Small Compounds Affecting RNA Elements (SCARE) in mRNA 3'UTRs (GA22-20110S)

for proteins yet more than 75% is transcribed into RNA. Thus, a large proportion of RNA is non-protein-coding including 3’UTRs of mRNAs with important regulatory functions. Therefore, targeting these proteins via ...

Biochemistry and molecular biology

  • 2022 - 2024
    • •
  • 11 747 tis. Kč
    • •
  • 11 456 tis. Kč
    • •
  • GA ČR
Project

RNA-binding proteins controlling translational repression of stored transcripts in developing male gametophyte (GA15-16050S)

characterisation of ribonucleoprotein particles formed around specific RNA-binding proteins. To achieve this goal, we aim to employ both candidate RNA-binding proteins and stored with an instant translation. Here ...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 8 714 tis. Kč
    • •
  • 8 714 tis. Kč
    • •
  • GA ČR
Project

Structure and function of the Trypanosoma brucei guide RNA binding protein 21 and its complex with the guide RNA molecule (GP204/04/P191)

of recognition and binding of the guide RNA (gRNA) molecules to guide-RNA binding protein 21 (gBP21). gBP proteins stimulate annealing of pre-mRNA to gRNA, which servesastemplate non-translatable mRNA...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 984 tis. Kč
    • •
  • 984 tis. Kč
    • •
  • GA ČR
Project

Translation regulation in plant dormant reproduction units - pollen and seeds (GA21-15856S)

of the mRNA activation mechanisms and investigate the role of specific regulatory proteinsThe phenomenon of translational regulation and mRNA storage has been studied - share mRNA storage mechanism that is highly ...

Plant sciences, botany

  • 2021 - 2023
    • •
  • 11 994 tis. Kč
    • •
  • 11 994 tis. Kč
    • •
  • GA ČR
Project

Depicting a functional model of NTP303 mRNA translational repression during tobacco pollen maturation (GPP501/11/P321)

encoding N-glycosylated p69 kDa protein is an essential component of the pollen tube, however, the encoded mRNAs are translationally repressed and stored within) imposed to repress the translation of NTP303 mRNA during pol...

ED - Fyziologie

  • 2011 - 2013
    • •
  • 3 034 tis. Kč
    • •
  • 3 034 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 3 574