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8 (0,08s) •

Project

Cytokinin and acute phase proteins in laboratory diagnosis and prognosis of human ovarian cancer. (IZ2258)

9F - 9

  • 1994 - 1996
    • •
  • 212 tis. Kč
    • •
  • 424 tis. Kč
    • •
  • MZ
Project

The interplay of arterial wall and perivascular adipose tissue in the initiation of atherogenesis (NV17-28103A)

The relationship of the content and proportion of pro-inflammatory M1 and anti-inflammatory M2 macrophages between the human artery and adjacent perivascular adipose tissue will be determined (tissues obtained in kidney transplantation procedure from...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2017 - 2020
    • •
  • 4 229 tis. Kč
    • •
  • 4 229 tis. Kč
    • •
  • MZ
Project

Regulatory mechanisms of innate immune cells in kidney transplantation (NV15-26883A)

The project is focused on the study of innate immune mechanisms in kidney transplantation. The parameters of human monocytes activation will be studied in early post-transplant period and in treatment complications (delayed graft function/rejection/i...

EC - Imunologie

  • 2015 - 2020
    • •
  • 7 027 tis. Kč
    • •
  • 6 955 tis. Kč
    • •
  • MZ
Project

Macrophage polarization and the fatty acid spectrum of cell membrane phospholipids of adipose tissue (NU20-01-00022)

We have recently published that the proportion of pro-inflammatory macrophages of human adipose tissue (CD14+, CD16+, CD36+++) correlates positively with the main risk factors of atherosclerosis – age, BMI and non-HDL cholesterol concentration. In a ...

Endocrinology and metabolism (including diabetes, hormones)

  • 2020 - 2023
    • •
  • 4 242 tis. Kč
    • •
  • 4 242 tis. Kč
    • •
  • MZ
Project

Effect of EXercise training and Omega-3 fatty acids on metabolic health and DYsfunction of Adipose tissue in elderly (NV16-29182A)

Aging is associated with development of disturbances of lipid and carbohydrate metabolism and with systemic pro-inflammatory state. The studies performed with elderly people suggests that these characteristics may be improved by physical activity and...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2016 - 2019
    • •
  • 14 354 tis. Kč
    • •
  • 13 324 tis. Kč
    • •
  • MZ
Project

New morphological, immunological and biochemical markers of carotid plaques vulnerability (NU22-02-00051)

Management of patients with hemodynamically significant asymptomatic carotid stenosis is a very controversial issue. It is important to have a widely available methodology able to identify patients at high risk for stroke originating from particular ...

Cardiac and Cardiovascular systems

  • 2022 - 2025
    • •
  • 4 038 tis. Kč
    • •
  • 4 038 tis. Kč
    • •
  • MZ
Project

Blood flow modelling in intracranial vessels in relationship to endothelium changes and development of intracranial aneurysms (NU22-08-00124)

Rupture of intracranial aneurysms (IA) leads to one of the most severe types of stroke with high morbidity and mortality. Deviations in hemodynamics inside an IA are associated with inflammation reaction in the vessels including activation of macroph...

Clinical neurology

  • 2022 - 2025
    • •
  • 16 132 tis. Kč
    • •
  • 16 132 tis. Kč
    • •
  • MZ
Project

Pericoronary adipose tissue – an active or passive player in atherosclerosis development? (NW25-02-00068)

Inflammatory changes in perivascular adipose tissue are associated with atherosclerotic changes in adjacent arteries, and this relationship is widely accepted. The principal question remains unanswered - what is the primary source of the inflammation...

Cardiac and Cardiovascular systems

  • 2025 - 2028
    • •
  • 6 009 tis. Kč
    • •
  • 6 009 tis. Kč
    • •
  • MZ
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