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8 435 (0,074s) •

Project

Turning copper proteins into photoenzymes (LUAUS25012)

1) Elucidate mechanisms and kinetics of enzymatic reactions catalyzed by multicopper oxidases, reveal functions of tryptophan and tyrosine residues proximal) Accelerate and alter enzymatic reactions of mul...

Physical chemistry

  • 2025 - 2028
    • •
  • 5 961 tis. Kč
    • •
  • 5 961 tis. Kč
    • •
  • MŠMT
Project

New enzymes and methods for chemoenzymatic synthesis of bioactive glycosides (GA203/01/1018)

Novel methods for enzymatic synthesis of bioactive glycosides based on aminosugars will be developed. New reaction conditions will be tested in enzymatic glycosylation to improve effectiveness of these reactions. N...

CE - Biochemie

  • 2001 - 2003
    • •
  • 6 664 tis. Kč
    • •
  • 3 794 tis. Kč
    • •
  • GA ČR
Project

Enzymatic synthesis of bioactive glycosides (OC 170)

development of methodoly of application of glykosylazides as donors for transglykosilation reactions with glykosidazes....

CE - Biochemie

  • 2007 - 2007
    • •
  • 132 tis. Kč
    • •
  • 132 tis. Kč
    • •
  • MŠMT
Project

Specific ion effects for proteins in solutions and related biologically relevant systems. (GA203/08/0114)

The mechanism of hydration of ions and interaction of ions with biomolecules play an important role in many natural and biotechnological processes. We plan within this proposal to combine computational and experimental tools with the aim to ...

CF - Fyzikální chemie a teoretická chemie

  • 2008 - 2012
    • •
  • 11 625 tis. Kč
    • •
  • 11 625 tis. Kč
    • •
  • GA ČR
Project

Theoretical Study of the Structure and Reaction Mechanism of Alcohol Dehydrogenase (IAA4055103)

, phenomena of metal substitution and reaction mechanism involving hydrogen transfer apply the accurate methods of quantum chemistry to study a very important enzymatic......

CE - Biochemie

  • 2001 - 2003
    • •
  • 1 665 tis. Kč
    • •
  • 786 tis. Kč
    • •
  • AV ČR
Project

Structure, dynamics, and reaction mechanism of catalytic RNA (IAA400040802)

catalysts. Although most today's enzymes are proteins, many key reactions are catalyzed backbone through a transesterification mechanism. The main aims is to elucidate their catalytic mechanism, which remains entirely elus...

CE - Biochemie

  • 2008 - 2011
    • •
  • 4 415 tis. Kč
    • •
  • 4 415 tis. Kč
    • •
  • AV ČR
Project

Selective enzymatic oxidations and deracemizations of natural products and biomolecules (OC09045)

and silychristin, preferably in their optically pure forms. We will study enzymatic preparation of quercetin for further biological studies. We will investigate oxidative reactions their molecular mechanism.......

CC - Organická chemie

  • 2009 - 2012
    • •
  • 1 760 tis. Kč
    • •
  • 1 760 tis. Kč
    • •
  • MŠMT
Project

Surface chemical reactivity of ceria in environmentally and biologically relevant reactions (GA25-15972S)

reactivity in environmental and biologically oriented reactions, such as hydrolytic methods. An integral part will be the study of the kinetics and mechanism of the relevant reactions to clarify the main reaction ...

Nano-materials (production and properties)

  • 2025 - 2027
    • •
  • 9 884 tis. Kč
    • •
  • 9 884 tis. Kč
    • •
  • GA ČR
Project

Studies on the non-enzymatic polymerization of mildly activated nucleotide precursors (GA22-25057S)

cyclic and acyclic nucleotides to participate in transphosphorylation reactions to self-assembling of the monomers prior to the polymerization reaction. Based, crystallization, and subsequent non-enzymatic template-free ...

Organic chemistry

  • 2022 - 2024
    • •
  • 4 464 tis. Kč
    • •
  • 4 386 tis. Kč
    • •
  • GA ČR
Project

Grand-canonical description of the chemical reactions at constant pH. (GA23-06909S)

the validity and predict the basic reaction mechanisms of metal complexes in biophysical and biochemical processes. Quantum mechanical methods combined with molecular modeling (QM/MM of the reaction center to be i...

Physical chemistry

  • 2023 - 2025
    • •
  • 7 197 tis. Kč
    • •
  • 6 645 tis. Kč
    • •
  • GA ČR
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