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1 842 (0,097s) •

Project

Focused on the liver portal triad understanding the Jagged1 signaling within the periportal mesenchyme (GA25-15821S)

The mesenchymal tissue is a critical compartment of the liver, playing effects of disrupted Jagged1 signaling on the mesenchymal tissue and hepatic arteries, point to an overlooked role of the Jagged1 role within t...

Developmental biology

  • 2025 - 2027
    • •
  • 9 513 tis. Kč
    • •
  • 9 513 tis. Kč
    • •
  • GA ČR
Project

Development of a unit for decellularization by supercritical CO₂, optimization of permeations and recipes for tissue decelularization and production of a bioactive scaffold equipped with mesenchymal (FW06010688)

on decellularized human tissue with subsequent mesenchymal stem cells. The basis will be the design of a decellularization unit for decellularization of tissues by supercritical CO₂, its implementation in the premises of t...

Transplantation

  • 2023 - 2027
    • •
  • 29 191 tis. Kč
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  • 20 186 tis. Kč
    • •
  • TA ČR
Project

Production and characterization of biologically active recombinant human ameloblastin -a hard tissue regeneration and differentiation inducing protein (GAP302/10/0427)

important biological functions - induction of mesenchymal hard tissue formation and reparative processes in calcified tissues. We want to overproduce recombinant in developing and healing bone and teeth hints on its involv...

EB - Genetika a molekulární biologie

  • 2010 - 2012
    • •
  • 3 990 tis. Kč
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  • 3 990 tis. Kč
    • •
  • GA ČR
Project

Spinal cord injury reconstruction using surface-modified biodegradable hydrogels with oriented pores seeded with mesenchymal stem cells (GA14-14961S)

Reconstructing damaged CNS tissue is one of the major issues in neuroscience. Chronic SCI is characterized by a posttraumatic cavity surrounded by a mesenchymal axonal regrowth across the lesion. The hydrogels in combination with

FH - Neurologie, neurochirurgie, neurovědy

  • 2014 - 2016
    • •
  • 6 300 tis. Kč
    • •
  • 6 300 tis. Kč
    • •
  • GA ČR
Project

Autologous cell based therapy for ischemic diabetic wounds preclinical and clinical trial (GA14-03540S)

mesenchymal stem cells (BM-MSC) and adipose tissue derived mesenchymal stem cells (AT-MSC...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2014 - 2018
    • •
  • 5 444 tis. Kč
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  • 5 444 tis. Kč
    • •
  • GA ČR
Project

The histopathology of middle ear, with the main topic of middle ear inflammation (NR8376)

Histopathology of middle ear cavity of newborns and infants. The main topic is mesenchymal tissue, pneumatisation of middle ear, epidermoid formation, amniotic fluid and pathology of ossicles. We will discuss about the pathology of ...

FF - ORL, oftalmologie, stomatologie

  • 2005 - 2007
    • •
  • 1 399 tis. Kč
    • •
  • 1 395 tis. Kč
    • •
  • MZ
Project

The histopathology of middle ear of newborns and infants (NK6189)

Histopathology of middle ear cavity of newborns and infants.The main topic is mesenchymal tissue,pneumatization of middle ear,epidermoid formation,amniotic fluid and pathology of ossicles and muscles. We will discuss about the patho...

FF - ORL, oftalmologie, stomatologie

  • 2000 - 2002
    • •
  • 777 tis. Kč
    • •
  • 762 tis. Kč
    • •
  • MZ
Project

Paracrine effect of mesenchymal stem cell-secretome and its modification for the treatment of spinal cord injury (GA17-03765S)

Paracrine action is a major mechanism attributed to mesenchymal stem cells (MSCs) beneficial effects in neural repair. MSCs produce a range of cytokines and neurotrophic effects, while MSC-secretome or conditioned media (CM) may cause ti...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2019
    • •
  • 5 238 tis. Kč
    • •
  • 4 851 tis. Kč
    • •
  • GA ČR
Project

Development of regenerative and advanced therapy medicinal products based on cultured mesenchymal stem cells from umbilical cord (TF03000037)

The goal is to develop an advanced therapy medicinal product based on cultured mesenchymal stem cells (MSCs) derived from umbilical cord tissue and intended for treatment of severe immune-mediated diseases and for regenerative medic...

EI - Biotechnologie a bionika

  • 2016 - 2019
    • •
  • 20 696 tis. Kč
    • •
  • 15 244 tis. Kč
    • •
  • TA ČR
Project

The role of Meis transcription factors in mesenchymal condensations during formation of the cranium (GA22-10660S)

cells or connective tissues. Cranial neural crest-derived mesenchyme condensates mesenchymal condensations. We will use spatial transcriptomics, RNA-seq, in situ......

Developmental biology

  • 2022 - 2024
    • •
  • 9 825 tis. Kč
    • •
  • 9 825 tis. Kč
    • •
  • GA ČR
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