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12 (0,082s)

Project

Complex surgery of the thyroid gland carcinoma with a stress on regional metastases. (IZ3179)

FD - Onkologie a hematologie

  • 1995 - 1997
  • 509 tis. Kč
  • 479 tis. Kč
  • MZ
Project

Integral approach to treatment of liver tumourous lesions. (IZ2185)

9F - 9

  • 1994 - 1996
  • 177 tis. Kč
  • 213 tis. Kč
  • MZ
Project

Optimal clinical and mathematical interpretation of tumor markers in the different periods of cancer diseases. (IZ3480)

FD - Onkologie a hematologie

  • 1996 - 1998
  • 412 tis. Kč
  • 396 tis. Kč
  • MZ
Project

Palliative treatment of colorectal cancer metastates using selective intraarterial chemotherapy and controlled ischemisation. (IZ2273)

9F - 9

  • 1994 - 1995
  • 81 tis. Kč
  • 162 tis. Kč
  • MZ
Project

Center of Cell Invasiveness in Embryonic Development and Tumour Metastases (LC06061)

The cells in multicellular organisms are spatially organized through cell-cell and cell-extracellular matrix interactions. Disruption of adhesive bonds results in enhanced cell motility and helps cells to become invasive - to degrade the basal membra...

FD - Onkologie a hematologie

  • 2006 - 2011
  • 64 683 tis. Kč
  • 64 683 tis. Kč
  • MŠMT
Project

Extension of established prognostic scores in brain metastases by microRNA profiling to tailor the post-operative personalized care (NV18-03-00398)

Brain metastases (BM) are the most often occurring intracranial tumors characterized by an unfavorable prognosis. Therapeutic options are limited and depend largely on the prognosis of patient which is currently predicted using prognostic scoring sys...

Oncology

  • 2018 - 2022
  • 12 078 tis. Kč
  • 11 599 tis. Kč
  • MZ
Project

Reaction of hippocampal neuronal population on stereotactic radiotherapy of extratemporal brain metastases The influence on the neurocognitive function and maintanance of quality of life (NV18-03-00469)

Quality of life (QoL) is currently emphasized during the treatment of bran metastases (BM). Stereotactic radiotherapy and radiosurgery (SRT/SRS) is an advanced technique that – apart from excellent local control – also induces less adverse effects in...

Oncology

  • 2018 - 2023
  • 7 086 tis. Kč
  • 6 999 tis. Kč
  • MZ
Project

Neoadjuvant Stereotactic Radiotherapy for Brain Metastasis - prospective trial NeoSTROBE (NW25-03-00278)

The main methods of treatment for brain metastases are radiotherapy and surgical resection. Among the radiation techniques, whole brain radiotherapy (WBRT) and targeted stereotactic radiotherapy (SRT) are used. In patients with metastatic brain invol...

Oncology

  • 2025 - 2028
  • 11 980 tis. Kč
  • 11 980 tis. Kč
  • MZ
Project

Structural MRI radiomic analysis for differential diagnosis of radiation injury and true progression after stereotactic radiotherapy of brain metastases (NU22-03-00159)

Stereotactic radiotherapy (SRT) is current standard of care for brain oligometastases. SRT is characterized by a high dose delivered in less than five fractions and with a steep dose gradient to surrounding healthy brain tissue. However, follow-up MR...

Oncology

  • 2022 - 2025
  • 7 016 tis. Kč
  • 7 016 tis. Kč
  • MZ
Project

Strategies for specific targeting of brain metastasis microenvironment for diagnostic and therapy (NU22-03-00318)

Brain metastases affect approximately 20% of patients with various solid cancers and are the most common malignant tumors of the central nervous system in adults. The median survival is less than one year and therapeutic options remain limited. As wi...

Radiology, nuclear medicine and medical imaging

  • 2022 - 2025
  • 12 326 tis. Kč
  • 12 326 tis. Kč
  • MZ
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