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18 (0,214s) •

Project

Modulations of mesolimbic ghrelin signalling – a new hope for methamphetamine addiction treatment? (GA21-30795S)

Methamphetamine addiction is a serious public health problem, treatment remains reduced the methamphetamine reinforcing and drug-seeking effects in rats CB1 antagonist) have been found to reduce the methamphetamine reinforc...

Substance abuse

  • 2021 - 2023
    • •
  • 5 464 tis. Kč
    • •
  • 5 464 tis. Kč
    • •
  • GA ČR
Project

Effect of methamphetamine on the first and second offspring generation in drug-abusing female rats. (NF7456)

to methamphetamine and its neurotoxic effects on dopaminergic and serotoninergic...

FH - Neurologie, neurochirurgie, neurovědy

  • 2003 - 2005
    • •
  • 1 904 tis. Kč
    • •
  • 1 893 tis. Kč
    • •
  • MZ
Project

Factors affecting healthy development of progeny of drug-abusing mothers (1A8610)

Experimental study of long-term changes after chronic methamphetamine application, the most common drug in the Czech Reublic. Differentiation of the extent of drug effect and the extent of the effect of postnatal care and breeding on individ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2009
    • •
  • 3 420 tis. Kč
    • •
  • 3 406 tis. Kč
    • •
  • MZ
Project

Methodology for Determination of Chemical Profiling of Drugs (VI20192022131)

The aim of the project is to create methodological procedure for determination of chemical profiles of methamphetamine, heroin and cocaine (hereinafter referred to as “drugs”) seized within criminal proceedings. Thanks to the determined drug...

Analytical chemistry

  • 2019 - 2022
    • •
  • 23 002 tis. Kč
    • •
  • 23 002 tis. Kč
    • •
  • MV
Project

A cohort of women using methamphetamine, heroin, and women in opioid substitution during pregnancy neonatal and long-term consequences for the child (NV16-28157A)

Methamphetamine- and opioid-dependence in pregnant women is a major public health issue internationally, associated with high health and social burden in women and their children. Study focuses on neonatal and long-term outcomes in children ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2016 - 2019
    • •
  • 3 741 tis. Kč
    • •
  • 3 741 tis. Kč
    • •
  • MZ
Project

Sensitization induced by prenatal methamphetamine exposure in adult rats (GA305/06/0283)

Drug abuse of pregnant women is a growing problem of last few decades. The effect of prenatal drug exposure may have devastating effect on the prenatal development that may be long-term or even permanent. One of the most common drugs abused by pregna...

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2008
    • •
  • 3 861 tis. Kč
    • •
  • 3 861 tis. Kč
    • •
  • GA ČR
Project

Active drug-seeking behavior in prenatally methamphetamine-exposed adult male and female rats (NS10509)

The aim of the planned project is to determine the effect of prenatal methamphetamine (MA) exposure on drug-seeking behavior in adulthood. The following drugs will be tested: (1) the same drug as prenatally (MA); (2) the related drugs (amphe...

FH - Neurologie, neurochirurgie, neurovědy

  • 2009 - 2011
    • •
  • 3 151 tis. Kč
    • •
  • 3 151 tis. Kč
    • •
  • MZ
Project

Determination of critical developmental period for methamphetamine effects in rats (GA14-03708S)

Methamphetamine (MA) is a frequently abused drug in pregnant drug-abusing women and is the most commonly used illicit drug in the Czech Republic. This drug passes through the placenta easily and can impair not only the mother but also the de...

FH - Neurologie, neurochirurgie, neurovědy

  • 2014 - 2016
    • •
  • 5 032 tis. Kč
    • •
  • 5 032 tis. Kč
    • •
  • GA ČR
Project

Impact of different environments on cognitive functions of adolescent male rats exposed prenatally to methamphetamine (GA18-03806S)

Children prenatally exposed to methamphetamine (MA), one of the most commonly abused drugs in pregnancy, are in great risk of developmental problems due to unfavorable health and social conditions. Using animal models, we demonstrated that M...

Neurosciences (including psychophysiology)

  • 2018 - 2020
    • •
  • 9 847 tis. Kč
    • •
  • 9 484 tis. Kč
    • •
  • GA ČR
Project

Does prenatal methamphetamine exposure induce cross-sensitization to drugs in adult male and female rats? (GA305/09/0126)

Drug abuse of pregnant women is a growing problem. The effect of prenatal drug exposure may have devastating effect on development of the body that may be long-term or even permanent. One of the most common drug abused by pregnant women is metham...

FH - Neurologie, neurochirurgie, neurovědy

  • 2009 - 2013
    • •
  • 5 487 tis. Kč
    • •
  • 5 487 tis. Kč
    • •
  • GA ČR
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