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437 (0,085s) •

Project

Transplantation of the embryonic cerebellar tissue and stem cells into the cerebellum of Lurcher mutant and normal mice (OC10038)

of adult Lurcher mutant and normal wild type mice and to examine the effect of transplantation on motor function of Lurcher mice. Lurcher mutant mice will be used as a natural model of hereditary olivocerebellar degenerati...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010 - 2011
    • •
  • 793 tis. Kč
    • •
  • 793 tis. Kč
    • •
  • MŠMT
Project

Processing of complex acoustical signals including vocalizations in inhibitory circuits of the central auditory system in mice models of autism and different types of sensorineural hearing loss. (LTAIN19201)

MICE AND IN PATHOLOGICAL STATES AIM 2. DETECTION OF C-FOS EXPRESSION IN THE IC, MGB, PAG, AMYGDALA AND HIPPOCAMPUS OF MICE AFTER STIMULATION WITH RECORDED EMISSIONS IN MICE IN RESPONSE TO SOUNDS OCCURRING AS PARTS OF VOCAL...

Neurosciences (including psychophysiology)

  • 2020 - 2022
    • •
  • 6 829 tis. Kč
    • •
  • 6 829 tis. Kč
    • •
  • MŠMT
Project

Impact of ghrelin and estrogen on metabolic syndrom of female obese mice (GA303/09/0744)

Ovariectomized (OVX) mice with diet-induced obesity (DIO) serve as a model of postmenopausal women with metabolic syndrome. In our preliminary study, these mice developed that inhibition of ghrelin is beneficial especially in OVX

CE - Biochemie

  • 2009 - 2011
    • •
  • 4 288 tis. Kč
    • •
  • 4 288 tis. Kč
    • •
  • GA ČR
Project

Genetic analysis of EPOR signal transduction in iron depleted erythropoiesis (GAP305/11/1745)

deficient mice (mk mice with DMT1 mutation) with a gain-of-function EPOR polycythemic mice (mtHEPOR) we will test our therapy-based hypothesis that prolonged EPOR/mtHEPOR mice in order to study EPO/EPOR-dependent ...

FD - Onkologie a hematologie

  • 2011 - 2014
    • •
  • 6 995 tis. Kč
    • •
  • 6 995 tis. Kč
    • •
  • GA ČR
Project

Mechanism involved in enteropathy and diabetes participation of food and bacterial antigens in triggering of autoimmunity (GA306/98/0433)

present in the gut of animal models of diabetes ( non-obese-diabetic mice, NOD ) and enteropathy ( immunodeficient athymic nude mice ) are involved in triggering autoimmune of microbial components in the triggering autoimmune respo...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1998 - 2000
    • •
  • 2 609 tis. Kč
    • •
  • 2 441 tis. Kč
    • •
  • GA ČR
Project

Functional and morphological study of brain plasticity in healthy and neurodefective mice under various condition (OC 152)

study of mechanism of plasticity functioning in processes of learning, memory and motorics...

FH - Neurologie, neurochirurgie, neurovědy

  • 2007 - 2010
    • •
  • 2 658 tis. Kč
    • •
  • 1 486 tis. Kč
    • •
  • MŠMT
Project

Vaccination efficacy in elderly A protein energy malnutrition model in old mice cohort (8J23AT004)

-energy malnutrition and vaccination / immunization in a cohort of old mice. Long-term and the consequences of experimental malnutrition in mice. It also increases the immune response the effectiveness of influenza vaccination and p...

Microbiology

  • 2023 - 2024
    • •
  • 190 tis. Kč
    • •
  • 190 tis. Kč
    • •
  • MŠMT
Project

The role of PPAR-alfa in the regulation of insulin sensitivity. (NB7429)

will be used to measure the changes of insulin sensitivity in fibrates-tretaed mice with diet-induced obesity/insulin resistance or transgenic mice with complete PPAR-alfa......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 3 134 tis. Kč
    • •
  • 3 035 tis. Kč
    • •
  • MZ
Project

New pharmacological interventions influencing energy homeostasis and development of insulin resistance/ type 2 diabetes mellitus (GAP303/10/1368)

will be tested in mice for their short-term effect on food intake, pain and anxiety, as well as for long-term effects in mice with diet-induced obesity with metabolic syndrome and A-ZIP mice with lipoatrophic diabetes.We h...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2010 - 2013
    • •
  • 9 715 tis. Kč
    • •
  • 9 715 tis. Kč
    • •
  • GA ČR
Project

Role of muscle thermogenesis in cold- and obesity-resistance in mice (GA22-07004S)

inbred strains of mice differing in succeptibility to obesity, we will characterize phenotyping, mice with ablation of AMP-activated protein kinase (AMPK) α2 gene, as well......

Endocrinology and metabolism (including diabetes, hormones)

  • 2022 - 2025
    • •
  • 8 571 tis. Kč
    • •
  • 8 470 tis. Kč
    • •
  • GA ČR
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