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The diagnostic, predictive and prognostic role of microRNA signature in rectal cancer (GA15-08239S)
of any diagnostic or predictive biomarkers. MicroRNAs are often shown mRNA. MicroRNAs are therefore promising candidates serving as a novel biomarkers for cancer. However, the role of microRNA in the genesis and progressio...
EB - Genetika a molekulární biologie
- 2015 - 2019 •
- 6 832 tis. Kč •
- 6 832 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2015 - 25. 4. 2019
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
MicroRNA biomarkers - new methods of quantification (TH01010244)
MicroRNA and especially their circulating forms provide a new dimension as noninvasive biomarkers for variety of diseases. However, characterization of microRNAs purpose technologies for quantification of microRNAs in cell...
EB - Genetika a molekulární biologie
- 2015 - 2017 •
- 8 400 tis. Kč •
- 4 950 tis. Kč •
- TA ČR
Řešení projektu: 1. 1. 2015 - 31. 12. 2017
Uznané náklady
Podpora ze státního rozpočtu (59%)
Poskytovatel: Technologická agentura ČR
Development of microRNA-based biomarkers for diagnostics of cancer chemoresistance (TH04010303)
The goal of the project is identification of new generation of microRNA-based biomarkers and their use for early diagnosis of certain types of cancer and prediction of chemoresistance of tumor to conventional therapy. The project is aimed to...
Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])
- 2019 - 2021 •
- 9 748 tis. Kč •
- 5 630 tis. Kč •
- TA ČR
Řešení projektu: 1. 1. 2019 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (58%)
Poskytovatel: Technologická agentura ČR
Industrial research and development of new DNA technology for human diagnostics next generation sequencing and microRNA (EG15_018/0004701)
Industrial research and development of new DNA technology for human diagnostics: next generation sequencing and microRNA...
FS - Lékařská zařízení, přístroje a vybavení
- 2015 - 2020 •
- 19 337 tis. Kč •
- 2 141 tis. Kč •
- MPO
Řešení projektu: 29. 9. 2015 - 11. 6. 2020
Uznané náklady
Podpora ze státního rozpočtu (11%)
Poskytovatel: Ministerstvo průmyslu a obchodu
Development of diagnostic panel of circulating microRNAs for non-invasive early diagnostics and follow-up of colorectal cancer patients (NT13549)
Our study is based on methodically novel and progressive approach based on microRNAs to identify cancer biomarkers in blood serum. The rationale of our project is to build diagnostic panel of microRNAs enabling early detection of CR...
FD - Onkologie a hematologie
- 2012 - 2015 •
- 9 419 tis. Kč •
- 9 419 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2012 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Implication of placenta-specific microRNAs in maternal circulation for diagnosis and prediction of placental insufficiency (GAP304/12/1352)
MicroRNAs (miRNAs) belong to a family of small non-coding RNAs (18-25 the presence of some microRNAs in peripheral blood of pregnant women and demonstrated placenta-specific microRNAs profile which are released into materna...
FK - Gynekologie a porodnictví
- 2012 - 2014 •
- 5 259 tis. Kč •
- 5 259 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2012 - 31. 12. 2014
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Identification and functional characterization of microRNAs with predictive significance in patients with glioblastoma (NT11214)
The main goal of our project is to extend knowledge about molecular mechanisms involved in glioblastoma carcinogenesis and invasivness by analysis of microRNA expression profiles in primary tumors and use our findings for prediction of respo...
FD - Onkologie a hematologie
- 2010 - 2013 •
- 5 548 tis. Kč •
- 5 548 tis. Kč •
- MZ
Řešení projektu: 1. 9. 2010 - 31. 12. 2013
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Identification and functional studies of microRNAs with predictive and prognostic significance in patients with colorectal cancer (NS9814)
The main goal of our project is contribution to the knowledge of molecular biology of colorectal carcinoma by analysis of microRNA expression profiles of the primary colorectal tumors and utilization of our results for improvement of recent ...
FD - Onkologie a hematologie
- 2008 - 2011 •
- 5 834 tis. Kč •
- 5 795 tis. Kč •
- MZ
Řešení projektu: 1. 7. 2008 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Utility of tissue/circulating microRNAs for response prediction and improvement of restaging accuracy in rectal cancer after neoadjuvant treatment (NV16-31765A)
Alteration of the microRNA regulatory network is one of the key events in pathogenesis of wide range of malignancies including rectal cancer. MicroRNAs are abundant and could be determined not only in tumor tissue, but also in blood...
FD - Onkologie a hematologie
- 2016 - 2019 •
- 14 599 tis. Kč •
- 14 599 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2016 - 31. 12. 2019
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Circulating tumor DNA and micro RNA for detection of minimal residual disease and recurrence of malignant melanoma in early stages (LTAUSA19080)
biopsy based on the detection of ctDNA and/or microRNA expression profiles-free interval - DFI) based on detection and quantification of ctDNA and microRNA disease based on detection and quantification of ctDNA and microRNA
Pathology
- 2020 - 2022 •
- 7 781 tis. Kč •
- 7 781 tis. Kč •
- MŠMT
Řešení projektu: 1. 1. 2020 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
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