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Projects

1 270 projects (0,233s) •

Project

Circulating tumor DNA and micro RNA for detection of minimal residual disease and recurrence of malignant melanoma in early stages (LTAUSA19080)

biopsy based on the detection of ctDNA and/or microRNA expression profiles of ctDNA and microRNA expression profiles in blood samples obtained in follow-up biomarkers(ctDNA and microRNA expression pro...

Pathology

  • 2020 - 2022
    • •
  • 7 781 tis. Kč
    • •
  • 7 781 tis. Kč
    • •
  • MŠMT
Project

The diagnostic, predictive and prognostic role of microRNA signature in rectal cancer (GA15-08239S)

of any diagnostic or predictive biomarkers. MicroRNAs are often shown mRNA. MicroRNAs are therefore promising candidates serving as a novel biomarkers for cancer. However, the role of microRNA in the genesis and progressio...

EB - Genetika a molekulární biologie

  • 2015 - 2019
    • •
  • 6 832 tis. Kč
    • •
  • 6 832 tis. Kč
    • •
  • GA ČR
Project

Identification of new prognostic markers and update on staging of locally advanced renal cell carcinoma by microRNA expression profiles analysis (NS10361)

Prognostic miRNAs, identified by analysis of miRNAs expression profiles obtained by use of Real-Time PCR miRNA Arrays or their targets on the protein level, enable identification of patients with LARC at high risk of disease progression and ...

FD - Onkologie a hematologie

  • 2009 - 2011
    • •
  • 4 174 tis. Kč
    • •
  • 3 988 tis. Kč
    • •
  • MZ
Project

Identification and functional characterization of microRNAs with predictive significance in patients with glioblastoma (NT11214)

The main goal of our project is to extend knowledge about molecular mechanisms involved in glioblastoma carcinogenesis and invasivness by analysis of microRNA expression profiles in primary tumors and use our findings for prediction...

FD - Onkologie a hematologie

  • 2010 - 2013
    • •
  • 5 548 tis. Kč
    • •
  • 5 548 tis. Kč
    • •
  • MZ
Project

Identification and functional studies of microRNAs with predictive and prognostic significance in patients with colorectal cancer (NS9814)

The main goal of our project is contribution to the knowledge of molecular biology of colorectal carcinoma by analysis of microRNA expression profiles of the primary colorectal tumors and utilization of our results for improvement o...

FD - Onkologie a hematologie

  • 2008 - 2011
    • •
  • 5 834 tis. Kč
    • •
  • 5 795 tis. Kč
    • •
  • MZ
Project

Circulating microRNAs as non-invasive markers of graft rejection in patients after heart transplantation (NV16-30537A)

Using expression profiling arrays we will identify intracellular (from endomyocardial biopsies) as well as circulating (from plasma, urine and peripheral blood mononuclear cells) miRNAs that will distinguish heart transplant patients with gr...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2016 - 2020
    • •
  • 15 167 tis. Kč
    • •
  • 14 149 tis. Kč
    • •
  • MZ
Project

Study od epithelial-to-mesenchymal transition associated microRNAs and genes as potential markers for prediction of risk and early detection of metastatic disease in renal cell carcinoma patients (NT13547)

The EMT status reflecting miRNAs identified by expression profiling analysis using Real-Time PCR miRNA Arrays or their target molecules on protein level will enable to identify RCC patients with increased risk of metastatic disease, and by t...

FD - Onkologie a hematologie

  • 2012 - 2015
    • •
  • 7 431 tis. Kč
    • •
  • 7 431 tis. Kč
    • •
  • MZ
Project

Integrated microRNA, mRNA expression profiling, linkage and correlation analyses for identification of genes underlying complex traits (GAP301/10/0290)

MicroRNAs (miRNAs) comprise a novel class of endogenous, small, non-coding RNAs that control gene expression and could be pivotal regulators in normal physiology as well profiles in mutliple tissues relevant to the pathogenesis of m...

EB - Genetika a molekulární biologie

  • 2010 - 2014
    • •
  • 6 393 tis. Kč
    • •
  • 6 393 tis. Kč
    • •
  • GA ČR
Project

Implication of placenta-specific microRNAs in maternal circulation for diagnosis and prediction of placental insufficiency (GAP304/12/1352)

placenta-specific microRNAs profile which are released into maternal circulationMicroRNAs (miRNAs) belong to a family of small non-coding RNAs (18-25 the presence of some microRNAs in peripheral blood of pregnant ...

FK - Gynekologie a porodnictví

  • 2012 - 2014
    • •
  • 5 259 tis. Kč
    • •
  • 5 259 tis. Kč
    • •
  • GA ČR
Project

Analysis of EGFR signalling and microRNA expression profiles in prediction of response to anti-EGFR therapy in colorectal cancer patients with wild-type KRAS (NT13860)

In the proposed project we are aiming idetification of the new molecular markers (effector molecules of EGFR signalling, microRNAs) enabling response prediction to anti-EGFR therapy in patients with metastastic colorectal cancer carrying wil...

FD - Onkologie a hematologie

  • 2012 - 2015
    • •
  • 6 455 tis. Kč
    • •
  • 6 455 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 1 270