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Faecal microbiota transplantation in irritable bowel syndrome a randomised double-blind cross-over study utilizing a mixed microbiota derived from healthy individuals (NV19-01-00127)
The proposed project is a clinical intervention trial testing whether transferring high-diversity faecal microbiota to subjects with irritable bowel syndrome improves the control of the disease. In contrast to previous works, we offer a rigo...
Other clinical medicine subjects
- 2019 - 2023 •
- 13 216 tis. Kč •
- 12 584 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2019 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (95%)
Poskytovatel: Ministerstvo zdravotnictví
The impact of gut microbiota on the onset and the course of anorexia nervosa in patients and in an experimental animal model (NU22-04-00010)
The study will follow the influence of the gut microbiota on the course describing altered gut microbiota and a reduced “core” microbiota in patients with AN compared to healthy controls (gut microbiota dysbiosis)....
Immunology
- 2022 - 2025 •
- 12 227 tis. Kč •
- 12 227 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2022 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Defined minimal microbiota in protection against foodborne pathogen Salmonella enterica (GA21-15621S)
in immunocompromised patients. A gastrointestinal microbiota of the human and pig shares similar characteristics compared to the mouse microbiota. Gnotobiotic piglet makes it possible to study the protection of the host by defined ...
Microbiology
- 2021 - 2024 •
- 10 530 tis. Kč •
- 10 530 tis. Kč •
- GA ČR
Řešení projektu: 1. 4. 2021 - 31. 3. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Linking prenatal stress to infant psychological development the role of gut microbiota and immune function (GA21-23288S)
these relations remain unclear. Recently, stressor-induced alterations in gut microbiota have. Additionally, immune function, which interacts closely with gut microbiota, is considered prenatal stress and microbiota or imm...
Psychology, special (including therapy for learning, speech, hearing, visual and other physical and mental disabilities);
- 2021 - 2024 •
- 5 820 tis. Kč •
- 5 820 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2021 - 30. 6. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Modification of gut microbiota in the treatment of insulin resistance a personalized approach (NV18-01-00040)
Gut microbiota may play a key role in many metabolic diseases, including type 2 resident microbiota towards reduced genetic diversity and to influence its metabolic composition or whether it is mediated, at least partly, by differen...
Endocrinology and metabolism (including diabetes, hormones)
- 2018 - 2022 •
- 18 028 tis. Kč •
- 17 804 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2018 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Gut microbiota in pharmacotherapy of digestive diseases (GA17-09869S)
Microbiota has a significant impact on the drug pharmacotherapy by still largely unknown mechanisms. We will analyze how microbiota influences microbiota and how changes in the gut microbiota by antibiotics, probio...
FR - Farmakologie a lékárnická chemie
- 2017 - 2021 •
- 9 948 tis. Kč •
- 9 783 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2017 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Grantová agentura České republiky
Diet and microbiota as modulators of gut inflammation and colon cancer (GA16-06326S)
microbiota has been recently suggested. Gut microbiota is metabolically active part and tumorigenesis. We will analyze the gut microbiota composition and products of its metabolism- and/or fat-rich diets) and gut micro...
EC - Imunologie
- 2016 - 2020 •
- 7 179 tis. Kč •
- 6 909 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 22. 7. 2020
Uznané náklady
Podpora ze státního rozpočtu (96%)
Poskytovatel: Grantová agentura České republiky
Gut microbiota and the role of food additives in the development of allergies and autoimmune diseases (GA15-09518S)
. According to current knowledge the abnormal composition of gut microbiota characterized by a change in the ratio of beneficial and harmful microbiota might be responsible important environmental factor influencing the composition ...
EC - Imunologie
- 2015 - 2019 •
- 5 688 tis. Kč •
- 5 688 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2015 - 25. 4. 2019
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Fecal microbiota transplantation in cancer patients treated with checkpoint inhibitor therapy. (NV19-03-00179)
Patient's microbiota influences the effectivity of cancer treatment with immunotherapy. Fecal microbiota transplantation (FMT) is a well established method, which responders to non-responders by FMT. Moreover, we will analyze the gu...
Oncology
- 2019 - 2023 •
- 12 486 tis. Kč •
- 12 397 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2019 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Dissecting the role of microbiota and specific bacterial strains in mouse juvenile growth under normal/poor nutritional conditions (GJ18-07015Y)
factor-1. Recently, microbiota has been identified as a key player in growth of the whole microbiota in monoassociated germ-free (GF) mice. This project aims in the context of conventional animals harboring complete microbiota<...
Immunology
- 2018 - 2022 •
- 3 442 tis. Kč •
- 3 442 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2018 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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