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1 722 (0,129s) •

Project

Comparative Genomics of Plant Mitochondria (LH15075)

Plant mitochondrial genomes contain large intergenic regions and often high level of structural variation in mitochondrial genomes. We propose to sequence mitochondrial genomes of (sub)species clo...

EB - Genetika a molekulární biologie

  • 2016 - 2017
    • •
  • 2 364 tis. Kč
    • •
  • 1 908 tis. Kč
    • •
  • MŠMT
Project

The mitochondrial genome and oxidative phosphorylation system in metabolic syndrome (OC08017)

the roleof mitochondrial OXPHOS system and mitochondrial genome in pathogenesis strains with identical nuclear genome but different haplotypes of mitochondrial DNAMitochondrial oxidative phosphor...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2008 - 2011
    • •
  • 1 706 tis. Kč
    • •
  • 1 706 tis. Kč
    • •
  • MŠMT
Project

Complex characterisation of myxozoan mitochondria Genome, proteome and ultrastructure approach (GA21-29370S)

and they have one of the highest genome reduction among all metazoans. Recently, first mitochondrial genome analyses revealed its unusual fragmentation into several circular of myxosporeans. We will focus on mitochondr...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2021 - 2024
    • •
  • 7 091 tis. Kč
    • •
  • 7 091 tis. Kč
    • •
  • GA ČR
Project

The role of mitochondrial respiration in tumour initiation and growth A mechanistic study (GC17-01192J)

Cancer cells are so dependent on mitochondrial mtDNA for their growth, that in case of damage to their mtDNA, they acquire mitochondrial genome from host cells. Horizontal transfer of mtDNA is required for tumour formation,...

EB - Genetika a molekulární biologie

  • 2017 - 2019
    • •
  • 7 860 tis. Kč
    • •
  • 7 860 tis. Kč
    • •
  • GA ČR
Project

Genetic causes of mitochondrial diseases due to deficiency of ATP synthase (NS9759)

Identification of nuclear genetic determinants of inborn isolated defects of mitochondrial ATPase using methods of molecular genetics and cell biology and unique collection of genomic DNA, fibroblast cell lines and tissue samples fr...

EB - Genetika a molekulární biologie

  • 2008 - 2011
    • •
  • 9 899 tis. Kč
    • •
  • 9 899 tis. Kč
    • •
  • MZ
Project

Evolution and fate of endosymbiotic organelles in stramenopiles (GA18-13458S)

will obtain new sequences of mitochondrial and plastid genomes and will perform and analyse the nuclear genomes and transcriptomes. We will combine the new sequence data with results of experimental characterization of

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2018 - 2020
    • •
  • 9 730 tis. Kč
    • •
  • 8 657 tis. Kč
    • •
  • GA ČR
Project

Phylogenetic analysis of mitochondrial genome of Myxozoa and Polypodium hydriforme (GP204/09/P519)

placement of Myxozoa and P. hydriforme based on the analyses of mitochondrial genome metazoan groups. The analyses of numerous mitochondrial genes and rearrangements......

EG - Zoologie

  • 2009 - 2011
    • •
  • 643 tis. Kč
    • •
  • 643 tis. Kč
    • •
  • GA ČR
Project

Dynamic changes of mitochondrial DNA and transcription profiles in Silene vulgaris (GA521/09/0261)

S. vulgaris is a natural model of mtch genomic fluidity, occurring also in some lineages of crop plants. We aim to analyze in details polymorphism in mitochondrial (mtch) DNA and in the transcription profiles of mtch genes of S. vul...

EB - Genetika a molekulární biologie

  • 2009 - 2012
    • •
  • 2 290 tis. Kč
    • •
  • 2 290 tis. Kč
    • •
  • GA ČR
Project

Cardiac ischemic tolerance of spontaneously hypertensive rats involvement of mitochondrial genome (GA13-10267S)

with replaced mitochondrial genome from more I/R resistant strains Brown Norway, Fischer 344 and Lewis. An attention will be devote to the role of mitochondrial membrane structures susceptibility to I/R injury and mito...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2013 - 2017
    • •
  • 10 690 tis. Kč
    • •
  • 10 690 tis. Kč
    • •
  • GA ČR
Project

Tower of Babel Mitochondrial-nuclear interactions in the gynodioecious species Silene vulgaris investigated with transcriptomics. (GA16-09220S)

Plant mitochondrial genomes are highly rearranged. We propose to utilize an unprecedented level of intraspecific diversity in plant mitochondrial DNA described in Silene vulgaris for the investigation of mitochondrial

EF - Botanika

  • 2016 - 2020
    • •
  • 4 964 tis. Kč
    • •
  • 4 857 tis. Kč
    • •
  • GA ČR
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