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Projects

40 projects (0,119s) •

Project

Localization of mitochondrion in the cell of oxymonads (GP204/08/P280)

Oxymonads are aminy the least studied eukaryotes despite several peculiar features, including the absence of a mitochondrion. The classical aerobic mitochondrion the view is held that the mitochondrion has accompanied eukar...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 1 096 tis. Kč
    • •
  • 1 096 tis. Kč
    • •
  • GA ČR
Project

Mitochondrion of Trypanosoma brucei enters the post-proteomic era (ME09005)

throughput effort of the Stuart lab, the proteome of the T. brucei mitochondrion complexes of proteins of unknown function, and the response of the mitochondrion to DNA......

EB - Genetika a molekulární biologie

  • 2009 - 2009
    • •
  • 478 tis. Kč
    • •
  • 478 tis. Kč
    • •
  • MŠMT
Project

Functional exploration of a novel cellular system critical for understanding the origin and early evolution of the mitochondrion (GA22-29633S)

The transformation of a bacterial endosymbiont into the mitochondrion, a crucial aspect of the evolution of the eukaryotic cell, remains incompletely the striking possibility that the mitochondrion ancestrally has a capability to se...

Cell biology

  • 2022 - 2024
    • •
  • 10 627 tis. Kč
    • •
  • 10 627 tis. Kč
    • •
  • GA ČR
Project

The role of ATP synthase structure in the biogenesis and bioenergetics of the unique Trypanosoma brucei mitochondrion (GA18-17529S)

, Trypanosoma brucei is an excellent model system as the singular mitochondrion and ATP-producing mitochondrion transitions to a streamlined tubular, cristae-lacking......

Biochemistry and molecular biology

  • 2018 - 2022
    • •
  • 6 731 tis. Kč
    • •
  • 6 512 tis. Kč
    • •
  • GA ČR
Project

Characterizaton of a novel deep-branching eukaryote with plesiomorphic mitochondria (GA21-30563S)

number of unique traits, including a possibly plesiomorphic mitochondrion that has never been found in any other mitochondrion. In addition, SUM-K has a novel......

Microbiology

  • 2021 - 2023
    • •
  • 6 315 tis. Kč
    • •
  • 6 315 tis. Kč
    • •
  • GA ČR
Project

Functional analysis of mitochondrial proteins in Trypanosoma brucei (GA204/06/1558)

Trypanosoma brucei and related kinetoplastid flagellates are early-branching protozoans responsible for serious diseases of man and animals. Their single cell, and in particular their mitochondrion, contain many unique features. We propose t...

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 2 770 tis. Kč
    • •
  • 2 770 tis. Kč
    • •
  • GA ČR
Project

Characterization of Fe-S cluster assembly in Trypanosoma brucei (GAP305/11/2179)

Fe-S cluster assembly is one of the most conserved cellular pathways, and also one of the key functions of the mitochondrion and derived organelles. Our intention is to characterize the function of all components of this pathway in the paras...

EB - Genetika a molekulární biologie

  • 2011 - 2014
    • •
  • 7 384 tis. Kč
    • •
  • 7 384 tis. Kč
    • •
  • GA ČR
Project

Transformation of the endosymbiont into the organelle. (GA13-29423S)

The transformation of the alphaproteobacterial endosymbiont into mitochondrion was accompanied by dramatic changes in the biogenesis of this new double membrane-bounded compartment. (i) the protein flow across the membranes reversed as the b...

EB - Genetika a molekulární biologie

  • 2013 - 2018
    • •
  • 7 798 tis. Kč
    • •
  • 7 798 tis. Kč
    • •
  • GA ČR
Project

Chromera velia as a model organism to study evolution of apicomplexans and chrompodellids (GA16-24027S)

of the unique mitochondrion of C. velia. A combination of bioinformatic approaches...

EF - Botanika

  • 2016 - 2019
    • •
  • 5 886 tis. Kč
    • •
  • 5 457 tis. Kč
    • •
  • GA ČR
Project

Determining the Effectors of Mitochondrion Remodeling During Procyclic Trypanosoma brucei Differentiation (GA17-22248S)

and metabolic remodeling of the single mitochondrion. Until recently, it was challenging...

EE - Mikrobiologie, virologie

  • 2017 - 2021
    • •
  • 6 648 tis. Kč
    • •
  • 6 240 tis. Kč
    • •
  • GA ČR
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