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4 533 (0,077s) •

Project

Identification of new diagnostic/predictive biomarkers and compounds applicable to personalized treatments of multidrug resistant tumors (LTC19020)

The aim of this project is identification and validation of new prognostic and predictive molecular biomarkers of multidrug resistence in solid tumors. New molecular biomarkers will be characterized in detail by a...

Human genetics

  • 2019 - 2022
    • •
  • 3 936 tis. Kč
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  • 3 936 tis. Kč
    • •
  • MŠMT
Project

Molecular genetics of tumor and cardiovascular diseases (EE2.3.20.0040)

is to create a specialized department of molecular genetics and the study of biomarkersThe aim is to multidisciplinary cooperation in the use of molecular genetic and serum biomarkers in the prediction and prevent...

EB - Genetika a molekulární biologie

  • 2011 - 2014
    • •
  • 33 688 tis. Kč
    • •
  • 33 688 tis. Kč
    • •
  • MŠMT
Project

Circulating microvesicles (microparticles and exosomes) for diagnosis of gynecological malignancies (NT12248)

. To identify cancer specific biomarkers we propose to combine molecular analysisReliable biomarkers are needed to improve diagnosis and therapy of gynecological cancer. The aim of the project is to identify molecular

FK - Gynekologie a porodnictví

  • 2011 - 2015
    • •
  • 6 321 tis. Kč
    • •
  • 6 321 tis. Kč
    • •
  • MZ
Project

Molecular and genetic biomarkers of ovarian cancer pathogenesis and resistance (NT14056)

of useful molecular biomarkers for prognosis and prediction of ovarian cancer is still missing. In this project, new candidate molecular biomarkers will be identified. For candidate molecular markers, the...

EB - Genetika a molekulární biologie

  • 2013 - 2015
    • •
  • 6 853 tis. Kč
    • •
  • 6 853 tis. Kč
    • •
  • MZ
Project

Mitochondrial optic neuropathies a complex genetic and metabolomic analysis to characterize molecular bases and to identify novel biomarkers (NU22-07-00614)

and by the lack of quantitative biomarkers of disease progression. We will use complex genetic, biochemical and molecular biology approaches in combination with detailed phenotyping plasma biomarkers for disease monitoring...

Biochemistry and molecular biology

  • 2022 - 2025
    • •
  • 13 769 tis. Kč
    • •
  • 13 769 tis. Kč
    • •
  • MZ
Project

Study of apoptosis inhibitors as diagnostic and predictive tumor biomarkers in lung cancer (NR7860)

Analysis of expression of apoptosis inhibitors by molecular and biochemical methods in tumor tissue, lung parenchyma, biopsy and cytological samples and sputum from lung cancer patients and study of their significance as tumor biomarkers...

FD - Onkologie a hematologie

  • 2004 - 2008
    • •
  • 9 173 tis. Kč
    • •
  • 8 553 tis. Kč
    • •
  • MZ
Project

Study of molecular pathogenesis of bone marrow failure and identification of clinically relevant biomarkers in hypoplastic myelodysplastic syndrome and acquired aplastic anemia (NU21-03-00565)

to hematopoietic cells by cytotoxic T-lymphocytes. However, the molecular mechanisms involved and AA will be performed in the proposed project to characterize the molecular basis of BM failure and to define clinically relevant ...

Hematology

  • 2021 - 2025
    • •
  • 12 775 tis. Kč
    • •
  • 12 383 tis. Kč
    • •
  • MZ
Project

Biomarkers mapping at the infiltration zone of glioblastomas and their topographic relationship to an early relapse. (NU23-03-00100)

, we cannot be sure that the molecular profile of residual disease is the same what is to describe cellular and molecular profile in glioblastoma core and peritumoral brain zone / at resection margins and to correlate the biomar...

Oncology

  • 2023 - 2026
    • •
  • 13 669 tis. Kč
    • •
  • 13 669 tis. Kč
    • •
  • MZ
Project

Innovative multifunctional magnetic nano- and microparticles for cell diagnostics (GCP207/12/J013)

Progress in medical diagnosis associated with fast discovery of molecular biomarkers by genome research is strongly hindered by very low concentration of required biomarkers in body fluids and by presence of other biomolecu...

CD - Makromolekulární chemie

  • 2012 - 2013
    • •
  • 1 209 tis. Kč
    • •
  • 1 209 tis. Kč
    • •
  • GA ČR
Project

Pathophysiology of dystonia – role of gene-environment interaction and common pathophysiological pathways (8F20001)

dystonia in patients by identification of clinical biomarkers; c) support the current clinical diagnosis of dystonia by molecular biomarkers derived from multi-omic in molecular neurobiology, cellular and system ...

Other medical science

  • 2020 - 2024
    • •
  • 5 217 tis. Kč
    • •
  • 5 217 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 4 533