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1 049 (0,098s)

Project

The role of neuroactive steroids in etiopathogenesis of mood and anxiety disorders (NT13890)

This research is to quantify a broad spectrum of steroids in patients with anxiety and mood disorders (AMD) and to gain data about the pathophysiological importance and clinical relevance of neuroactive and neuroprotective steroids ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2012 - 2015
  • 9 646 tis. Kč
  • 9 646 tis. Kč
  • MZ
Project

Detection of neuroanatomical risk factors for bipolar disorder (NR8786)

We will perform MRI volumetry of the brain in offspring of parents with bipolar disorder, both unaffected and affected by mood disorders and matched healthy controls, in order to detect primary neuroanatomical risk factors ...

FL - Psychiatrie, sexuologie

  • 2006 - 2008
  • 3 921 tis. Kč
  • 3 772 tis. Kč
  • MZ
Project

Electrophysiological correlates of emotional neurocircuits in depression, bipolar affective disorder and healthy population. (NT12024)

disorders and to the improvement and acceleration of mood disorders diagnosis disorders and healthy subjects. The elucidation of neuronal processes associated......

FL - Psychiatrie, sexuologie

  • 2011 - 2015
  • 5 641 tis. Kč
  • 5 641 tis. Kč
  • MZ
Project

Neuropsychiatric Research Center (LN00B122)

The main objective of the proposed research center is to study neurobiological basis of the most serious mental disorders - schizophrenia and affective disorders. Research topics are approached simultaneously using models of basic r...

FH - Neurologie, neurochirurgie, neurovědy

  • 2000 - 2004
  • 95 084 tis. Kč
  • 77 560 tis. Kč
  • MŠMT
Project

Stationary and mobile devices to support circadian synchronization, treatment and prevention of mental disorders through full spectrum-light phototherapy (FW02020025)

. The proposed devices are intended to prevent or support treatment of mood disorders, such as seasonal affective disorder (SAD), bipolar disorder, postnatal depression, and many with neuropsychiatric disorders...

Psychiatry

  • 2020 - 2023
  • 15 600 tis. Kč
  • 12 423 tis. Kč
  • TA ČR
Project

Prediction of relapse in bipolar affective disorder by means of telemetric actigraphy and social rhytmicity assessment. (NT14387)

In total, 50 patients with the bipolar affective disorder diagnosis (according to ICD-10), will be followed for 18 months. A continuous, 24-hour telemetric monitoring of the actigraphic record will be performed during the study period. Subje...

FL - Psychiatrie, sexuologie

  • 2013 - 2015
  • 3 280 tis. Kč
  • 3 280 tis. Kč
  • MZ
Project

Genomics of physiological regulations in bipolar disorder (NU23-04-00534)

We propose to conduct genomic study of the longterm course of bipolar disorder. Bipolar disorder is a serious illness characterized by recurrent episodes of mania and high risk of relapse. We will study 450 patients with bipolar

Psychiatry

  • 2023 - 2026
  • 10 117 tis. Kč
  • 10 117 tis. Kč
  • MZ
Project

Developmental dynamics of clinical and neurophysiological features in children and adolescents at genetic risk of bipolar affective disorder (NV17-32478A)

Prospective, cohort, observational study, of children and adolescents at risk of bipolar disorder (high-risk offspring, HRO). The objective is to identify clinical and laboratory markers of the risk of mood disorder. Sixty...

FL - Psychiatrie, sexuologie

  • 2017 - 2021
  • 7 872 tis. Kč
  • 7 587 tis. Kč
  • MZ
Project

Mitochondrial dysfunctions in bipolar affective disorder (NV15-28616A)

This project is focused on extension of knowledge related to pathophysiological processes associated or provoking bipolar affective disorder (BD), new diagnostic markers of the disease, which can be easily examined in blood samples. Clinical...

FL - Psychiatrie, sexuologie

  • 2015 - 2018
  • 7 502 tis. Kč
  • 7 502 tis. Kč
  • MZ
Project

Effect of lithium on Na+/K+-ATPase activity and functional consequences of oxidative stress; from animal model to bipolar patients (GA17-07070S)

Lithium is a unique therapeutic agent and has held the key position in the management of mood disorders for more than half a century. One of the advanced models triphosphate, Na+/K+-ATPase. Dysfunction of Na+/K+-ATPase during bipola...

ED - Fyziologie

  • 2017 - 2021
  • 7 291 tis. Kč
  • 6 685 tis. Kč
  • GA ČR
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