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65 (0,119s)

Project

Prediction of Stimulation Efficacy in Epilepsy (PRESEnCE) (NV19-04-00343)

Proposed project is focused on the prediction of neurostimulation methods (vagal nerve stimulation, deep brain stimulation) efficacy in patients with epilepsy. Neurostimulation leads to significant seizure reduction in approximately 50% of implanted...

Clinical neurology

  • 2019 - 2023
  • 8 856 tis. Kč
  • 8 856 tis. Kč
  • MZ
Project

Non-invasive stimulation of deep brain structures to modulate working memory (NW25-04-00142)

As global demographics shift towards an aging population, neurodegenerative disorders like Lewy body diseases (LBDs) pose significant healthcare challenges. LBDs, characterized mainly by motor symptoms, lead also to cognitive decline, severely impact...

Neurosciences (including psychophysiology)

  • 2025 - 2028
  • 14 427 tis. Kč
  • 14 427 tis. Kč
  • MZ
Project

Modulation of cognition and brain connectivity by noninvasive brain stimulation in patients with mild cognitive impairment due to Alzheimer’s disease (NV16-31868A)

Alzheimer’s disease (AD) has a detrimental impact on cognitive functions. Based on our pilot studies results in patients with neurodegenerative brain diseases we aim for promoting the brain plasticity and improving cognition by noninvasive brain stim...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
  • 7 743 tis. Kč
  • 7 743 tis. Kč
  • MZ
Project

Modulation of functional connectivity of the large scale cortical networks by STN DBS (NV16-33798A)

Deep brain stimulation (DBS) is an effective long-term treatment for motor symptoms in advanced Parkinson's disease (PD). The most frequently used target is the subthalamic nucleus (STN). For some patients, the beneficial motor effects may be accompa...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
  • 8 881 tis. Kč
  • 8 881 tis. Kč
  • MZ
Project

STN-DBS outcomes in Parkinson´s disease the influence of vascular, cardiovascular, metabolic, and inflammatory co-morbidities (NU21-04-00445)

Deep brain stimulation (DBS) is an established treatment for late motor symptoms in Parkinson’s disease (PD). Although DBS is generally a successful therapy, it has limitations including insufficient clinical effects and adverse side effects. The eff...

Clinical neurology

  • 2021 - 2024
  • 11 803 tis. Kč
  • 11 803 tis. Kč
  • MZ
Project

Implication of cognitive reserve in non-pharmacological intervention outcomes (NU21-04-00652)

Cognitive reserve (CR) can be defined as a gradual accumulation of neural resources and their adaptability (i.e. efficiency, capacity, flexibility) due to genetic and/or life-long environmental factors, that mitigate cognitive effects of age-related ...

Neurosciences (including psychophysiology)

  • 2021 - 2025
  • 9 440 tis. Kč
  • 9 440 tis. Kč
  • MZ
Project

Bioartificial organs and tisues (OK 189)

ED - Fyziologie

  • 1996 - 1997
  • 657 tis. Kč
  • 590 tis. Kč
  • MŠMT
Project

Predictive Factors in Cochlear Implants (IZ3166)

FP - Ostatní lékařské obory

  • 1995 - 1997
  • 609 tis. Kč
  • 593 tis. Kč
  • MZ
Project

New electrophysiological exminations for neuro-opthalmological diagnostics (IZ3230)

FP - Ostatní lékařské obory

  • 1995 - 1997
  • 504 tis. Kč
  • 368 tis. Kč
  • MZ
Project

The effect of transcranial direct current stimulation on visual attention in mild cognitive impairment – a combined MRI and non-invasive brain stimulation study (NV18-04-00256)

Alzheimer’s disease (AD) is the most common neurodegenerative disease. It progressively causes the breakdown of cognitive functions and impairs quality of life for patients and their caregivers. In addition to memory impairment, visual attention is a...

Clinical neurology

  • 2018 - 2022
  • 6 444 tis. Kč
  • 6 425 tis. Kč
  • MZ
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