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1 026 (0,071s)

Project

Strategy of oral immunization significance for systemic and mucosal immunity and use for prevention and therapy (VS96149)

Possibilities of modulation of mucosal and systemic immunity after oral immunization will be studied. The effect of various adjuvants, carriers and vectors on induction of protective immunity or oral tolerance will...

EA - Morfologické obory a cytologie

  • 1996 - 2000
  • 16 931 tis. Kč
  • 14 895 tis. Kč
  • MŠMT
Project

Vaccines for induction of mucosal and systemic immunity (IBS5020311)

oral vaccines for mucosal immunization against selected human and veterinary fusions to the mucosal immune system and the induction of strong, specific and protective mucosal immune responses tha...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
  • 6 070 tis. Kč
  • 5 365 tis. Kč
  • AV ČR
Project

Systemic and mucosal immune response after adjuvant mucosal immunization with inactivated influenza virus (GA310/02/0467)

Efficient mucosal immunization should be optimal for protection against, will be exploited in mucosal immunization by inactivated influenza virus and its subunits. Mice, guinea pigs and ferrets will be immunize...

EC - Imunologie

  • 2002 - 2004
  • 2 907 tis. Kč
  • 2 907 tis. Kč
  • GA ČR
Project

Environmental factors, mucosal immunity and regulatory T cells in pathogenesis and prevention of type 1 diabetes (T1D) (IAA5020405)

and gut microflora on the development of protective mucosal immunity in T1D. We gut mucosalimmunity in genetically-susceptible individuals. Mucosal surfaces represent the major interface with the outer environment. The dev...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2007
  • 2 581 tis. Kč
  • 2 181 tis. Kč
  • AV ČR
Project

Evolution of mucosal antimicrobial immunity (GA206/07/0378)

Mucosal surfaces represent important entrance gateway for infection, where they have to overcome efficient immune mechaisms. The proposed project is focused on the study of mucosal defense mechanisms in the model oligochate...

EG - Zoologie

  • 2007 - 2011
  • 5 427 tis. Kč
  • 5 427 tis. Kč
  • GA ČR
Project

Inflammatory bowel disease From immunopathogenetic mechanisms to the development of potencial vaccine (IAA5020205)

of immunoregulatory functions and impairment of the mucosal immune response to normal bacterial murine models of human disease, 3) to manipulate the mucosal immune responses by mucosal administration of b...

EC - Imunologie

  • 2002 - 2006
  • 6 168 tis. Kč
  • 4 688 tis. Kč
  • AV ČR
Project

Methods of eradication of production diseases of cattle - bovine viral diarrhoea - mucosal disease and paratuberculosis (QI101A094)

The aim of the project is to introduce methods of eradication of two economicaly important diseases of cattle - bovine viral diarrhoea - mucosal disease and paratuberculosis. During solution of the project, vaccine against BVD-MD will be dev...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2010 - 2014
  • 16 926 tis. Kč
  • 15 134 tis. Kč
  • MZe
Project

Molecular mechanisms of the effector phase of transplantation reaction after mucosal immunisation (GA310/99/D044)

The proposed project extends the research of cellular and molecular mechanisms of transplantation immunity and tolerance in the experimental models of mucosal immunization in mechanisms of transplantation reactions between ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1999 - 2002
  • 273 tis. Kč
  • 273 tis. Kč
  • GA ČR
Project

Molecular mechanisms of the effector phase of transplantation reaction after mucosal immunisation (GP310/02/D162)

The proposed project extends the research of cellular and molecular mechanisms of transplantation immunity and tolerance in the experimental models of mucosal immunization in mechanisms of transplantation reactions betweenr...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2002 - 2005
  • 675 tis. Kč
  • 675 tis. Kč
  • GA ČR
Project

Effect of probiotic lactobacilli on the development of allergy in an experimental model of human disease (IAA500200710)

modulate the ontogenetic development of mucosal and systemic innate and acquired immunity andto study the effect of mucosally applied strains of lactobacilli (LThe way how probiotics beneficially affect the immune...

EC - Imunologie

  • 2007 - 2011
  • 3 030 tis. Kč
  • 3 030 tis. Kč
  • AV ČR
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