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536 (0,167s) •

Project

Mucosal tolerance in models of orthotopic corneal transplantation studies of the mechanisms and clinical potential (GA310/99/0360)

mechanisms of mucosal tolerance in transplantation system and designing new therapeutic during the induction and maintenance of mucosal tolerance. The project will enable antigens, to study a possibility to induce...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1999 - 2001
    • •
  • 1 858 tis. Kč
    • •
  • 1 308 tis. Kč
    • •
  • GA ČR
Project

Mucosal tolerance in a murine model of corneal transplantation (ME 300)

Study of cellular and molecular mechanisms of rejection and tolerance of orthotopic corneal allografts in the experimental murine model. Study of potencial of the mucosal tolerance as a strategy for suppression of the immun...

EC - Imunologie

  • 1998 - 2000
    • •
  • 2 631 tis. Kč
    • •
  • 935 tis. Kč
    • •
  • MŠMT
Project

Strategy of oral immunization significance for systemic and mucosal immunity and use for prevention and therapy (VS96149)

Possibilities of modulation of mucosal and systemic immunity after oral immunization will be studied. The effect of various adjuvants, carriers and vectors on induction of protective immunity or oral tolerance will be tested. Bacill...

EA - Morfologické obory a cytologie

  • 1996 - 2000
    • •
  • 16 931 tis. Kč
    • •
  • 14 895 tis. Kč
    • •
  • MŠMT
Project

Effect of probiotic lactobacilli on the development of allergy in an experimental model of human disease (IAA500200710)

will determine the sensitization and induction of mucosal tolerance to allergens. modulate the ontogenetic development of mucosal and systemic innate and acquired immunity andto study the effect of mucosally appli...

EC - Imunologie

  • 2007 - 2011
    • •
  • 3 030 tis. Kč
    • •
  • 3 030 tis. Kč
    • •
  • AV ČR
Project

Intranasal vaccination in prevention of autoimmune diseases (NS10340)

Mechanisms of induction of mucosal protective immunity by intranasal administration of autoantigens using bioptic material of human nasal mucosa and mouse models of type 1. diabetes and ulcerative colitis. Role of NALT (Nasal associated lymp...

EC - Imunologie

  • 2009 - 2011
    • •
  • 2 561 tis. Kč
    • •
  • 2 561 tis. Kč
    • •
  • MZ
Project

The role of lipopolysaccharide content of the diet in the induction of oral tolerance studies in germ-free mice with modified TLR signaling (GP310/09/P182)

microbiota and food antigens. The mucosal immune system has evolved to balance the need is called oral tolerance. The mechanisms responsible for establishing and maintaining oral tolerance are incompletely understood. Howe...

EC - Imunologie

  • 2009 - 2011
    • •
  • 1 292 tis. Kč
    • •
  • 1 292 tis. Kč
    • •
  • GA ČR
Project

Analysis of mucosal cell populations participating in chronic intestinal inflammation (ME 178)

Analysis of mucosal cell populations participating in chronic intestinal inflammation.The aims of the project are: 1. To identify cell interactions which participate in pathogenetic mechanism of intestinal inflammation. 2. To elucidate the r...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1998 - 2000
    • •
  • 3 050 tis. Kč
    • •
  • 850 tis. Kč
    • •
  • MŠMT
Project

Molecular mechanisms of the effector phase of transplantation reaction after mucosal immunisation (GA310/99/D044)

The proposed project extends the research of cellular and molecular mechanisms of transplantation immunity and tolerance in the experimental models of mucosal immunization. The expression of effector molecules that are involved in t...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1999 - 2002
    • •
  • 273 tis. Kč
    • •
  • 273 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanisms of the effector phase of transplantation reaction after mucosal immunisation (GP310/02/D162)

The proposed project extends the research of cellular and molecular mechanisms of transplantation immunity and tolerance in the experimental models of mucosal immunization. The expression of effector molecules that are involved in t...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2002 - 2005
    • •
  • 675 tis. Kč
    • •
  • 675 tis. Kč
    • •
  • GA ČR
Project

Inflammatory bowel disease From immunopathogenetic mechanisms to the development of potencial vaccine (IAA5020205)

of immunoregulatory functions and impairment of the mucosal immune response to normal bacterial murine models of human disease, 3) to manipulate the mucosal immune responses by mucosal administration of bacterial antigens ...

EC - Imunologie

  • 2002 - 2006
    • •
  • 6 168 tis. Kč
    • •
  • 4 688 tis. Kč
    • •
  • AV ČR
  • 1 - 10 out of 536