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917 (0,119s) •

Project

Targeted inhibition of BCL2 family proteins in experimental therapy of diffuse large B-cell lymphoma (DLBCL) (NV15-27757A)

Diffuse large B-cell lymphoma (DLBCL) represents the most prevalent type of non-Hodgkin lymphomas (NHL) in the Western hemisphere. BCL2 and MCL1 belong to key regulators of intrinsic (mitochondrial) apoptosis. BCL2 was repeatedly associated with poor...

FD - Onkologie a hematologie

  • 2015 - 2018
    • •
  • 6 991 tis. Kč
    • •
  • 6 991 tis. Kč
    • •
  • MZ
Project

Intrinsic resistance to shear-mode fatigue crack growth in metallic materials (GJ17-15716Y)

experimental methodology for determination of intrinsic resistance to shear-mode fatigue in modes II and III and of the criterion for mode I branching and verification understanding of mechanisms of shear-mode cra...

JL - Únava materiálu a lomová mechanika

  • 2017 - 2018
    • •
  • 3 110 tis. Kč
    • •
  • 3 110 tis. Kč
    • •
  • GA ČR
Project

Mechanisms of embryonic stem cells early differentiation (IAA500520809)

The goal of our research is to elucidate the mechanism of and factors that govern the earliest steps of cells differentiation, with focus on when it initiates, when it becomes determined and what makes it irreversible on a molecular level. Our model ...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 2 553 tis. Kč
    • •
  • 2 553 tis. Kč
    • •
  • AV ČR
Project

Theoretical and experimental analysis of the light propagation in magnetooptical planar and periodical structures (ME 175)

on the following areas : - mode conversion in thin films with magnetic ordering - specification of the dispersion relations for guided modes - study of linear and quadratic magnetooptic effects - application of dark mode s...

BH - Optika, masery a lasery

  • 1998 - 2001
    • •
  • 1 720 tis. Kč
    • •
  • 520 tis. Kč
    • •
  • MŠMT
Project

Rheology of magnetorheological fluids subjected to non-uniform magnetic fields - pinch mode (GF21-45236L)

Magnetorheological (MR) fluids can operate in the following modes: flow, shear, squeeze, and gradient pinch. The operating principle of MR fluids in pinch mode appears to be based on different mechanisms compared to the other mo...

Electrical and electronic engineering

  • 2021 - 2024
    • •
  • 2 485 tis. Kč
    • •
  • 2 485 tis. Kč
    • •
  • GA ČR
Project

Intrinsic Localized Modes in Alkali Halides (GPP204/11/P404)

The aim of this projectis to examine the role of intrinsic localized modes in simple anharmonic discrete lattices, in order to make a consistent reference study of such systems. In particular, we would like to check whether the anharmonic lo...

BM - Fyzika pevných látek a magnetismus

  • 2011 - 2013
    • •
  • 1 516 tis. Kč
    • •
  • 1 516 tis. Kč
    • •
  • GA ČR
Project

Humanized patient-derived murine xenografts for experimental therapy of hematologic malignancies and for the study of in vivo acquired drug-resistance (NV19-08-00144)

Hematologic malignancies represent 5th most common type of tumor in the Czech Republic. Patient-derived murine xenografts (PDXs) derived by injection of primary tumor cells into immunodeficient mice became standard tools for confirmation of experimen...

Hematology

  • 2019 - 2022
    • •
  • 16 966 tis. Kč
    • •
  • 16 966 tis. Kč
    • •
  • MZ
Project

Assessment of area environmental resistance concerning the transport (1P04OC350.001)

Inventory of transport modes. the transport modes road and rail will be described in relation to the environmental and spatial balance......

DI - Znečištění a kontrola vzduchu

  • 2004 - 2006
    • •
  • 2 197 tis. Kč
    • •
  • 1 097 tis. Kč
    • •
  • MŠMT
Project

Research of rheological behavior of rocks at static and vibrational loading. (GP105/08/P307)

The samples of rock will be loaded at rheological mode as static as vibrational at vibrational loading mode is in format peak-valey. Becouse one test at rheological vibrational loading mode in this format (peak-valey) prese...

DH - Báňský průmysl včetně těžby a zpracování uhlí

  • 2008 - 2010
    • •
  • 617 tis. Kč
    • •
  • 617 tis. Kč
    • •
  • GA ČR
Project

Metrology and quality control of optical infrastructure of 5G and VHCN networks (FW03010551)

The main aim of the project is the development of a calibration set prototype for measuring and testing devices of single- and multi-mode optical infrastructures are expected, first including a calibration set for measuring devices in single...

Electrical and electronic engineering

  • 2021 - 2023
    • •
  • 12 414 tis. Kč
    • •
  • 8 140 tis. Kč
    • •
  • TA ČR
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