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1 840 (0,086s) •

Project

The effect of epilepsy and seizures of different etiology on activity-dependent myelination (GA25-17580S)

Activity-dependent myelination is recognized as one of the forms of neural plasticity when neuronal activity-dependent changes in myelin patterns along axons can attention has been focused on studying the activity-dependent myel...

Neurosciences (including psychophysiology)

  • 2025 - 2027
    • •
  • 8 976 tis. Kč
    • •
  • 8 976 tis. Kč
    • •
  • GA ČR
Project

Design and optimization of ultra-short echo-time sequence for reliable detection of myelin content in the human brain by magnetic resonance imaging. (GA15-12607S)

of the brain. There are two main obstacles to a reliable detection of myelin sheaths: 1 correcting for eddy-current induced image distortions, based on the measurement of k for the direct myelin measurement.......

FS - Lékařská zařízení, přístroje a vybavení

  • 2015 - 2017
    • •
  • 6 592 tis. Kč
    • •
  • 6 592 tis. Kč
    • •
  • GA ČR
Project

Detection of point mutations i Cx32, MPZ, EGR2 and PMP22 genes in patients with inherited peripheral neuropathies without 17p11.2-12 rearrangement (NF6504)

Sequencing analysis of Charcot-Marie-Tooth type 1 disorders genes Cx32, MPZ, EGR2 and PMP22 in patients from present collection of Czech patients with inherited peripheral neuropathies without the 17 p rearrangement.......

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 1 138 tis. Kč
    • •
  • 1 138 tis. Kč
    • •
  • MZ
Project

Detection of mutations in the GDAP1, LITAF, PRX and NEFL genes as newly discovered possible causes of inherited neuropaties Charcot-Marie-Tooth - extended investigation in the large cohort of at least 300 Czech families without the most common mutations. (1A8254)

To continue the long term project of elucidation of possible causes of inherited peripheral neuropathies by the extended analysis of recently discovered candidate genes - mainly LITAF, GDAP1, PRX and NEFL in a large previously collected cohort of at ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2004 - 2006
    • •
  • 2 686 tis. Kč
    • •
  • 2 661 tis. Kč
    • •
  • MZ
Project

Combinatorial approach to myelin and/or beta-sheet breakers. Implication for the therapeutic approaches to Alzheiner's and prion diseases (GA203/02/1379)

The project is divided into the synthetic, biological and physico-chemical parts . In the synthetic part we intent to carry out the synthesis of bis-intercalator peptide library functionalized with 9-amino acridine and to prepare a peptide fragment f...

CC - Organická chemie

  • 2002 - 2004
    • •
  • 1 840 tis. Kč
    • •
  • 1 327 tis. Kč
    • •
  • GA ČR
Project

Altered proportional and functional characteristics of particular neutrophil subsets as a possible trigger of relapses in patients with autoimmune neurological disorders of CNS (NU23-05-00462)

spectrum disorders (NMOSD), multiple sclerosis (MS), and myelin oligodendrocyte...

Immunology

  • 2023 - 2026
    • •
  • 11 685 tis. Kč
    • •
  • 11 685 tis. Kč
    • •
  • MZ
Project

Determination of D-aminoacids in proteins of selected human tissues (GA203/00/P038)

Occurence, origin and function of D-aminoacids (DAMAs) in the proteins are not yet fully understood.The DAMAs have been detected in the human enamel, dentin, erythrocytes, white brain matter, myelin end eye lens. Anomalous occurrence of DAMA...

CB - Analytická chemie, separace

  • 2000 - 2002
    • •
  • 100 tis. Kč
    • •
  • 100 tis. Kč
    • •
  • GA ČR
Project

Hormonal alterations in patients with multiple sclerosis (NU20-04-00450)

and decreased ability of CNS to produce myelin sheaths. Gender differences in prevalence...

Clinical neurology

  • 2020 - 2024
    • •
  • 6 956 tis. Kč
    • •
  • 6 699 tis. Kč
    • •
  • MZ
Project

imSearch ? Image searching system based on visual similarities (TA02010477)

in image data based on visual similarity. The aim is to develop methods and software that will allow automatic search in databases with millions or more images. Query to searchhas not text form, but takes the form of an image

IN - Informatika

  • 2012 - 2014
    • •
  • 5 074 tis. Kč
    • •
  • 2 769 tis. Kč
    • •
  • TA ČR
Project

Tools for imaging device identification, authentication, and image reconstruction (VG20102013064)

, an authentication, and image reconstruction, respectively. The project output will enable an identification of the imaging device (digital cameras, camcoders), it will exclude the possibility of intentional post-processing changes...

JC - Počítačový hardware a software

  • 2010 - 2013
    • •
  • 8 773 tis. Kč
    • •
  • 8 773 tis. Kč
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  • MV
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