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Projects

2 572 projects (0,14s) •

Project

New approaches to reduce negative economical impacts of plant pathogens from the genus Xanthomonas (LTC18009)

The project aims are to validate the use of the latest technologies and principles as tools to reduce the negative impacts of significant plant pathogen Xanthomonas campestris pv. Campestris ( Xcc). The suitability of the planned approaches....

Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

  • 2018 - 2020
    • •
  • 3 880 tis. Kč
    • •
  • 3 880 tis. Kč
    • •
  • MŠMT
Project

The application of new methods of genomic analysis in cases of rare genetic based diseases with negative results of genetic and genomic analyses. (NV19-08-00137)

in ~40 selected cases from our previous studies, in which we have negative results read length sequencing (Oxford Nanopore, PacBio) and our ability to correlate......

Health-related biotechnology

  • 2019 - 2023
    • •
  • 14 485 tis. Kč
    • •
  • 14 485 tis. Kč
    • •
  • MZ
Project

Molecular epidemiology of invasive meningococcal disease in the Czech Republic. (NV15-34887A)

strains by classical nucleotide sequence-based typing methods and antigen gene sequencing, implementation of new sequencing methods, i.e. whole-genome sequencing of agents in culture-negative cases of inv...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2015 - 2018
    • •
  • 6 650 tis. Kč
    • •
  • 6 329 tis. Kč
    • •
  • MZ
Project

Targeted NEXT-GEN sequencing as a tool for identification of the new breast cancer susceptibility genes in high-risk patients (NT14054)

Candidate genetic BC predisposition factors will be identified using the next-gen sequencing on SOLiD4 analyzer. Entire coding sequence of >250 selected genes isolated by exon trapping will be analyzed in 300 samples of high-risk (B...

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 7 202 tis. Kč
    • •
  • 7 202 tis. Kč
    • •
  • MZ
Project

Collaboration with CIMMYT on the study of diversity and evolution of maize B chromosome (LTT19007)

mays). We will accumulate novel data using molecular, cytogenetics, sequencing of available germplasm bank accessions for presence of B chromosomes; sequencing genes sequences on B chromosomes using FISH; analysis of di...

Plant sciences, botany

  • 2019 - 2023
    • •
  • 5 979 tis. Kč
    • •
  • 5 979 tis. Kč
    • •
  • MŠMT
Project

Role of dominant susceptibility genes in breast tumorigenesis - RNA-based analyses (NR9051)

cancerfamilies negative for mutations in genes BRCA1 and BRCA2. The role of BRCA1, BRCA2, p53 sequence variants in susceptibility genes will be analyzed by PCR-based methods truncatedprotein products will be sequenced.......

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 2 936 tis. Kč
    • •
  • 2 808 tis. Kč
    • •
  • MZ
Project

Immunogenetics in the Next Generation Sequencing era Deciphering the pathogenetic mechanisms in lymphoproliferative disorders (GJ19-23424Y)

Immunogenetic sequence analysis is a powerful tool in basic research aimed at identifying the mechanisms underlying lymphomagenesis and the emergence of high-throughput to the Anaplastic Lymphoma Kinase (ALK) positive and negative s...

Human genetics

  • 2019 - 2022
    • •
  • 5 860 tis. Kč
    • •
  • 5 860 tis. Kč
    • •
  • GA ČR
Project

Whole-genome sequencing-based epidemiology and analysis of genetic and physiological features that are associated with the spread of methicillin-resistant and susceptible strains of Staphylococcus (NU23-09-00080)

importance of S. aureus, coagulase-negative staphylococci (CoNS) have not been considered-negative staphylococci, including strains with resistance to methicillin and other will be analysed by whole-genome sequencing (WGS)...

Microbiology

  • 2023 - 2026
    • •
  • 5 158 tis. Kč
    • •
  • 5 158 tis. Kč
    • •
  • MZ
Project

Characterization of genetic predisposition to ovarian cancer using Next Gene Sequencing analysis (NV15-27695A)

negatively tested for BRCA1/2 mutations and 300 anonymous non-ca controls using next gen sequencing (NGS) and bioinformatics analysis. Detected alterations will be confirmed by Sanger sequencing; candidate alterations of u...

FD - Onkologie a hematologie

  • 2015 - 2018
    • •
  • 7 982 tis. Kč
    • •
  • 7 516 tis. Kč
    • •
  • MZ
Project

Identification of genetic factors contributing to hereditary breast cancer development and prognosis (NV15-28830A)

negatively tested in previous genetic analyses using whole exome sequencing. Using mutations could be identified using panel next-gen sequencing (NGS). Current project......

EB - Genetika a molekulární biologie

  • 2015 - 2018
    • •
  • 8 539 tis. Kč
    • •
  • 8 539 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 2 572