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4 972 (0,12s) •

Project

A new method of prophylaxis, decontamination, diagnostics and therapy afer intoxication with nerve agents and yperits (OPUOFVZ200603)

preparation against nerve agent intoxication by means of toxicological methods reactivatorsand to find the reactivator able to reactivate nerve agent-inhibited AChE regardless of the type of nerve agent. The validation of ...

FP - Ostatní lékařské obory

  • 2006 - 2008
    • •
  • 8 842 tis. Kč
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  • 7 462 tis. Kč
    • •
  • MO
Project

Cellular and extracellular environment for the axon regeneration following injury of the spinal roots and peripheral nerves (GA309/00/0407)

In contrast to the CNS environment, the peripheral nerves of mammals provide degeneration thatresults in formation of immature Schwann cells. The cells restore molecules by Schwann cells and suitable content of the...

FH - Neurologie, neurochirurgie, neurovědy

  • 2000 - 2002
    • •
  • 2 235 tis. Kč
    • •
  • 1 855 tis. Kč
    • •
  • GA ČR
Project

Biomarkers of Novichok nerve agent poisoning (VK01020171)

Novichok nerve agents are highly toxic chemical warfare agents. They are probably more efficient than better known G and V nerve agents (for example VX). The lack of published methods of the Novichok determination, laboratory diagno...

Analytical chemistry

  • 2023 - 2025
    • •
  • 2 148 tis. Kč
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  • 2 148 tis. Kč
    • •
  • MV
Project

Identification of changes in glutamatergic pathways specific for sporadic form of Alzheimer's disease in human neurons and astrocytes induced from patient's cells (NU20-09-00437)

) are currently being sought. The main aim of the project is to create a model of cell cultures suitable for monitoring changes in the biology of nerve cells (neurons), the role of nerve cells in the forma...

Neurosciences (including psychophysiology)

  • 2020 - 2023
    • •
  • 12 650 tis. Kč
    • •
  • 12 526 tis. Kč
    • •
  • MZ
Project

Functional replacements for nerve tissue regeneration fabricated using advanced 3D printing techniques (NU23-08-00243)

and polycaprolactone with defined biological properties with respect to cell adhesion as nerve conduits for peripheral nerve regeneration in neurology and neurosurgery.......

Materials engineering

  • 2023 - 2026
    • •
  • 15 609 tis. Kč
    • •
  • 15 609 tis. Kč
    • •
  • MZ
Project

*Auto-injector prevention of nerve agent exposure. (FI-IM2/104)

*Auto-injector for prevention of nerve agent exposure and for mitigation their action for military and civilian persons....

CI - Průmyslová chemie a chemické inženýrství

  • 2005 - 2007
    • •
  • 37 731 tis. Kč
    • •
  • 12 530 tis. Kč
    • •
  • MPO
Project

Improvement and practical implementation of peripheral nerve decellularization technology for the purpose of developing a novel biological product - decellularized scaffold, for the allogeneic (TM01000031)

The aims of the project are: 1) Development and optimization of automated decellularization of human nerve tissue – utility model 2) The development of a new modern therapy product - Decellularized nerve allograft - functional sampl...

Health-related biotechnology

  • 2020 - 2023
    • •
  • 16 898 tis. Kč
    • •
  • 4 462 tis. Kč
    • •
  • TA ČR
Project

Spatio-temporal changes of cytokines in the dorsal root ganglia of experimental neuropathic pain models induced by unilateral nerve injury (GA309/07/0121)

Peripheral nerve injury results in the peripheral neuropathic pain. However ganglia (DRG) induced by nerve injury are related with spontaneous ectopic activity nerve. It is assumed that cytokines play a key role for signali...

FH - Neurologie, neurochirurgie, neurovědy

  • 2007 - 2009
    • •
  • 3 231 tis. Kč
    • •
  • 3 231 tis. Kč
    • •
  • GA ČR
Project

Novichok nerve agents - toxicity and countermeasures (GA22-12859S)

Weapons Convention, nerve agents still represent a permanent threat both in the military and civilian sector. A novichok is a group of nerve agents of the fourth generation, which differ in their scaffold from known nerve ...

Toxicology

  • 2022 - 2024
    • •
  • 8 793 tis. Kč
    • •
  • 8 793 tis. Kč
    • •
  • GA ČR
Project

Countermeasure against chemical terrorism - development of new antidotes against nerve agents (ME 865)

searching for the most spreaded pesticides as potentional nerve agents, test of ability to inhibite in vitro enzyme Acetylcholinesterase (AChE)......

CA - Anorganická chemie

  • 2006 - 2009
    • •
  • 1 668 tis. Kč
    • •
  • 1 668 tis. Kč
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  • MŠMT
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