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Examination of differentiation potential of dental pulp stem cells (GP304/07/P307)
stem cells (osteocytes, chodrocytes, fibrocytes, adipocytes) and/or neural crest-derived stem cells (neurons and glia of PNS, smooth muscle, melanocyte). The main goalDental pulp including dental pulp stem cel...
EA - Morfologické obory a cytologie
- 2007 - 2009 •
- 1 167 tis. Kč •
- 1 167 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2007 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The role of Meis transcription factors in mesenchymal condensations during formation of the cranium (GA22-10660S)
cells or connective tissues. Cranial neural crest-derived mesenchyme condensatesMany cartilage and skeletal elements in the cranium arise from neural crest cells. These multipotent cells...
Developmental biology
- 2022 - 2024 •
- 9 723 tis. Kč •
- 9 723 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2022 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Study the role of transcription factors of Meis family during development of neural crest cells (GA18-00514S)
Understanding the genetic basis regulating development of neural crest cells (NCC) is one of major goals in developmental biology. Our team uses Cre/loxP system in transgenic mice to inactivate specific transcription factor...
Biomaterials (as related to medical implants, devices, sensors)
- 2018 - 2020 •
- 8 939 tis. Kč •
- 8 108 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2018 - 31. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (91%)
Poskytovatel: Grantová agentura České republiky
Origin of Merkel cells in mammals and birds (GA304/99/0680)
on embryonic avian chimeras, we support the neural crest cell origin of Merkel cells, mutants with abnormal neural crest cell migration, seem to be a suitable modelfor cell orig...
EA - Morfologické obory a cytologie
- 1999 - 2001 •
- 1 664 tis. Kč •
- 1 504 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1999 - 1. 1. 2001
Uznané náklady
Podpora ze státního rozpočtu (90%)
Poskytovatel: Grantová agentura České republiky
Craniofacial development of non-teleost fishes as a unique model of the vertebrate head evolution (GA19-18634S)
aims to describe developmental patterns of cranial placodes and rostral neural crest cells, to analyse their significance for the configuration of the rostral of vertebrates. Genesis of our ‘new head’ was fundamentally lin...
Developmental biology
- 2019 - 2022 •
- 8 060 tis. Kč •
- 8 060 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2019 - 30. 6. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Differentiation of human embryonic stem cells into odontogenic lineages (GAP304/11/1418)
and their differentiated derivatives (neural crest progenitors already developed in our lab) by factors exist, with proper cell sources and their directed differentiation into odontogenic embryonic stem cells (hES...
EI - Biotechnologie a bionika
- 2011 - 2014 •
- 7 697 tis. Kč •
- 7 697 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2011 - 8. 12. 2014
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Mandibular arch morphogenesis and embryological origin of jaws what does "maxillary" and "mandibular" really mean in the context of facial developmen (KJB5111403)
Using cell tracing markers and transplantations as well as in situ hybridization we would like to perform detailed cellular and molecular analyses of the trigeminal neural crest cell regionalization of the Mexican ...
EG - Zoologie
- 2004 - 2006 •
- 908 tis. Kč •
- 908 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Akademie věd České republiky
The role of c-myb gene in the early vertebrate embryogenesis (GA304/03/0463)
in gastrulation, neurulation and in the fate determination of multipotent cells of the Hensen's node, neural crest and somites. Similarly, the possible significance of c-myb for the formation of tissues derived from the no...
EA - Morfologické obory a cytologie
- 2003 - 2005 •
- 3 993 tis. Kč •
- 3 993 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Intercellular interactions in malignant melanoma - experimental study (GAP304/12/1333)
that embryonic microenvironment significantly attenuates the aggressiveness of melanoma cells with purpose to better understand interactions of these cells in the tumor employing cell......
FO - Dermatovenerologie
- 2012 - 2015 •
- 10 080 tis. Kč •
- 10 080 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2012 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Novel molecular targets and prognostic markers in neuroblastoma Identification guided by mapping neural crest cell differentiation programs (NW24-07-00017)
in the neural crest cell-derived sympathoadrenal lineage. Recent single-cell transcriptomics differentiation trajectories and cell state clusters relevant to NB heterogeneity. We have shown in NB cell...
Oncology
- 2024 - 2027 •
- 11 970 tis. Kč •
- 11 970 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2024 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
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