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10 (0,095s) •

Project

Optimalization of newborn screening of cystic fibrosis (NS9986)

associated protein(PAP). The major aim of this study is to compare IRT/PAP scheme with new designed IRT/PAP/DNA scheme from the point of specifity, sensitivity and cost......

FG - Pediatrie

  • 2008 - 2011
    • •
  • 10 604 tis. Kč
    • •
  • 10 597 tis. Kč
    • •
  • MZ
Project

Molecular mechanisms and evolution of RNA polyadenylation in euglenophyte plastids (GA21-19664S)

Euglenophytes are a group of charismatic unicellular algae with plastids evolved via a complex process of secondary endosymbiosis. The model species, Euglena gracilis, has for long been employed in research on basic biological questions and is a prom...

Genetics and heredity (medical genetics to be 3)

  • 2021 - 2023
    • •
  • 10 396 tis. Kč
    • •
  • 10 119 tis. Kč
    • •
  • GA ČR
Project

Aryl-sulfotransferases and their application in sulfated metabolite preparation (GA19-00043S)

and carotenoids, and monosaccharides. A set of sequences encoding different PAPS-independent...

Biochemistry and molecular biology

  • 2019 - 2023
    • •
  • 4 705 tis. Kč
    • •
  • 4 705 tis. Kč
    • •
  • GA ČR
Project

Role of DNA conformation and DNA grooves in protein - DNA recognition. Model studies. (GA204/96/0287)

will be investigated using oligonucleotides containing noncanonical bases in the sequences...

CE - Biochemie

  • 1996 - 1998
    • •
  • 747 tis. Kč
    • •
  • 480 tis. Kč
    • •
  • GA ČR
Project

Implicit relations in text coherence (GA17-03461S)

(e.g. noncanonical word order, complex syntactic structure etc.). The research...

AI - Jazykověda

  • 2017 - 2021
    • •
  • 3 318 tis. Kč
    • •
  • 2 577 tis. Kč
    • •
  • GA ČR
Project

Regulation of translation initiation during meiotic maturation of pig oocytes by protein factors associated with mRNA 3'-end (GA524/07/1087)

poly(A) polymerase (PAP) to the end of the mRNA and in such a way...

ED - Fyziologie

  • 2007 - 2009
    • •
  • 2 335 tis. Kč
    • •
  • 2 335 tis. Kč
    • •
  • GA ČR
Project

The molecular mechanisms of noncanonical 3' terminal RNA tailing and its role in the metabolism of coding and noncoding RNAs (GA20-19617S)

Eukaryotic RNAs undergo a wide variety of posttranscriptional modifications, such as base modifications or nontemplated 3'-end tailing. The 3' terminal RNA uridylation plays diverse roles in RNA metabolism acting in both, production of functional RNA...

Biochemistry and molecular biology

  • 2020 - 2022
    • •
  • 10 824 tis. Kč
    • •
  • 10 806 tis. Kč
    • •
  • GA ČR
Project

Development of method for the investigation of the organelle reduction process in Preaxostyla protists (GP13-22333P)

sexual cycles or noncanonical genetic code in several oxymonad species...

EA - Morfologické obory a cytologie

  • 2013 - 2016
    • •
  • 1 626 tis. Kč
    • •
  • 1 626 tis. Kč
    • •
  • GA ČR
Project

The role of beta-arrestin in achieving Wnt-signaling specificity (GC204/09/J030)

in noncanonical pathways has been described lately, most of them involving Dsh or trimeric G...

EB - Genetika a molekulární biologie

  • 2009 - 2011
    • •
  • 3 888 tis. Kč
    • •
  • 3 888 tis. Kč
    • •
  • GA ČR
Project

The function of the TRAMP4 complex in the formation of 3'-ends of mRNAs in Saccharomyces cerevisiae (GA17-20388S)

Yeast RNA polymerase II (RNAPII) synthesizes protein-coding and non-coding RNAs (ncRNAs). There are two different mechanisms of RNAPII transcription termination, both of them regulated by the phosphorylation level of RNAPII C-terminal domain (CTD). I...

EB - Genetika a molekulární biologie

  • 2017 - 2021
    • •
  • 8 435 tis. Kč
    • •
  • 8 240 tis. Kč
    • •
  • GA ČR
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