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3 013 (0,127s) •

Project

Nonenzymatic glycosylation of proteins and nucleic acids in diabetes mellitus, ageing and other diseases. (PL22)

ED - Fyziologie

  • 1991 - 1994
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Project

Investigation of posttranslational modifications of proteins with carbonyl compounds by using MALDI-TOF mass spectrometry and capillary electrophoresis. (ME 230)

Investigation of posttranslational modifications of proteins with carbonyl compounds by using MALDI-TOF mass spectrometry and capillary electrophoresis. In this project three types of protein modification will be studied: reactions ...

CB - Analytická chemie, separace

  • 1998 - 2000
    • •
  • 1 314 tis. Kč
    • •
  • 264 tis. Kč
    • •
  • MŠMT
Project

*Development and practical testing of biocide preparats with the concentration on effectivity increase and widening the range of application (FR-TI1/177)

*The project objective is R&D and testing reasonably priced innovative combination of antimicrobial substances used as disinfectants, biocides for wide use in personal, household and professional environment. Biocides are substances used for biologic...

FM - Hygiena

  • 2009 - 2012
    • •
  • 13 008 tis. Kč
    • •
  • 7 776 tis. Kč
    • •
  • MPO
Project

Estimation of collagen and its modifications in tissues based on marker peptide fragments (GA203/00/D032)

It is proposed to apply advanced (capillary) electromigration methods for the characterization and localization of nonenzymatic posttranslational modifications arising from the interactions of vascular wall collagen with (i) metabolites cont...

CB - Analytická chemie, separace

  • 2000 - 2003
    • •
  • 1 268 tis. Kč
    • •
  • 647 tis. Kč
    • •
  • GA ČR
Project

The antioxidative protection in chloroplasts and senescence initiation in tobacco plants (GP522/05/P558)

enzymatic and nonenzymatic) and at the damage caused by free radicals during senescence this issue by a detailed study of enzymatic and nonenzymatic antioxidative protection......

ED - Fyziologie

  • 2005 - 2007
    • •
  • 1 131 tis. Kč
    • •
  • 1 131 tis. Kč
    • •
  • GA ČR
Project

The study of processes associated with lipid peroxidation in model human cell lines (GA16-14631S)

cellular structures. 15-F2t-isoprostane (15-F2t-IsoP), a product of nonenzymatic...

EB - Genetika a molekulární biologie

  • 2016 - 2020
    • •
  • 4 086 tis. Kč
    • •
  • 3 939 tis. Kč
    • •
  • GA ČR
Project

Effect of protein hydration shell on the stability of protein complexes. (GPP205/12/P729)

Protein-protein interactions are at the basis of almost all cellular processes, but plays an active part in determining the structure and dynamics of both proteins and protein complexes. However, the exact molecula...

CF - Fyzikální chemie a teoretická chemie

  • 2012 - 2017
    • •
  • 2 037 tis. Kč
    • •
  • 2 037 tis. Kč
    • •
  • GA ČR
Project

Study of the interaction between 14-3-3 protein and regulator of G protein signaling RGS3. (IAA501110801)

protein?dependent regulation of function of RGS3 protein. 14-3-3 proteins are regulatory molecules that bind to other proteins in a phosphorylation dependent manner. RGS proteins function both as GTPase a...

BO - Biofyzika

  • 2008 - 2012
    • •
  • 5 095 tis. Kč
    • •
  • 5 095 tis. Kč
    • •
  • AV ČR
Project

Molecular basis of the 14-3-3 protein-dependent regulation of protein kinase activity (GA19-00121S)

14-3-3 proteins, a family of highly conserved dimeric proteins ubiquitously proteins including many disease-relevant protein kinases. However, our understanding of how the 14-3-3 proteins regulate the acti...

Biochemistry and molecular biology

  • 2019 - 2023
    • •
  • 8 340 tis. Kč
    • •
  • 8 034 tis. Kč
    • •
  • GA ČR
Project

Study of WD-protein function in actinomycetes (IAA5020207)

Proteins with WD40 motif are directly involved in signal transduction and transport. The function of WD40 repeats themselves in particular proteins, insofar as their function is known, consists in protein-protein i...

EB - Genetika a molekulární biologie

  • 2002 - 2005
    • •
  • 3 839 tis. Kč
    • •
  • 3 186 tis. Kč
    • •
  • AV ČR
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