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60 (0,098s) •

Project

Notch size effect in creep/fatigue (GA106/96/0332)

The proposal aims to elucidate the notch size effect on the service life) to define the critical notch size below which a notch has no effect on the service lifeof a notched structure, (2) to separate the influence...

JL - Únava materiálu a lomová mechanika

  • 1996 - 1998
    • •
  • 1 421 tis. Kč
    • •
  • 900 tis. Kč
    • •
  • GA ČR
Project

Notch signalling at the context of cellular metabolism. (GAP305/11/0126)

Activation of the Notch pathway leads to contrasting tissue-specific effects. Is there a link between cellular metabolic status and the outcome of Notch signaling of Drosophilagenome, the power of Drosophila genetics, established RN...

EB - Genetika a molekulární biologie

  • 2011 - 2013
    • •
  • 3 930 tis. Kč
    • •
  • 3 930 tis. Kč
    • •
  • GA ČR
Project

Notch sensitivity of superalloy single crystals under creep and creep/high-cycle-fatigue loading (OC 522.80)

The aim of the project is to determine the effect of notches on the resistance of superalloy single crystals against creep and creep/high-cycle-fatigue loading. The programme covers both the mechanical testing of notched single crys...

JL - Únava materiálu a lomová mechanika

  • 1998 - 2003
    • •
  • 7 179 tis. Kč
    • •
  • 2 060 tis. Kč
    • •
  • MŠMT
Project

Effect of mean stress on fatigue strength of bodies containing small notches (GA106/00/0171)

on the fatigue strength of bodies containing small surface notches. The reason for this study is the fact that there is no procedure for the evaluation of small surface notches limit on the notch size will be measured for ...

JL - Únava materiálu a lomová mechanika

  • 2000 - 2002
    • •
  • 2 081 tis. Kč
    • •
  • 1 352 tis. Kč
    • •
  • GA ČR
Project

Research of influence of finishing and progressive methods of machining on function properties of design notches in term possible catastrophic effects (GA101/09/0504)

materials, dry machining) to the fatigue strength of design notches. Conclusion will be the optimization of the notch from the point of view the applied method of machining at the formation of notch and finishing of surfac...

JQ - Strojní zařízení a nástroje

  • 2009 - 2012
    • •
  • 4 189 tis. Kč
    • •
  • 4 129 tis. Kč
    • •
  • GA ČR
Project

Disentangling the Notch signalling pathway in Myxozoa (GJ19-25536Y)

Notch signalling is among the oldest known signalling pathways of metazoans. To extend the knowledge on Notch signalling we will study the basal metazoan group understanding of the evolution of Notch signalling in basal met...

Developmental biology

  • 2019 - 2023
    • •
  • 5 178 tis. Kč
    • •
  • 5 178 tis. Kč
    • •
  • GA ČR
Project

The role of sirtuins in Notch signalling and Drosophila development (GA14-08583S)

Sirt1 and Notch signalling has emerged suggesting Sirt1 as a metabolic sensor for the Notch pathway. Our own data suggest that the role of Sir2 (the Drosophila ortholog the Notch pathway both positively or negatively depen...

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 4 560 tis. Kč
    • •
  • 4 560 tis. Kč
    • •
  • GA ČR
Project

Influence of the inner and middle ear pathology on the bone conduction of the sound waves (NK5871)

The origin and mechanism of Carhart´s notch from the point of different order of stapes fixation; Carhart notch and electric bone-conduction audiometry.Direct measurement of bone conduction;Intraoperative bone conduction audiometry....

FF - ORL, oftalmologie, stomatologie

  • 2000 - 2002
    • •
  • 1 924 tis. Kč
    • •
  • 1 924 tis. Kč
    • •
  • MZ
Project

Metabolic stress as regulator of Notch signalling (GA17-17529S)

proteins with the primary aim to secure cell survival. Notch pathway has been shown for this pathway. We would like to explore how is Notch signalling affected by two types data will help to elucidate how metabolic stress modulates...

EB - Genetika a molekulární biologie

  • 2017 - 2019
    • •
  • 5 758 tis. Kč
    • •
  • 5 758 tis. Kč
    • •
  • GA ČR
Project

Microstructural aspects of notch sensitivity of superalloy single crystals (IAA2041002)

In 1998 the Institute of Physics of Materials joined the EU programme COST 522. In this project IPM deals with the effect of notches on lifetime of hi-tech superalloy single of the effect of notches on deformation and lifetime would...

JL - Únava materiálu a lomová mechanika

  • 2000 - 2002
    • •
  • 4 506 tis. Kč
    • •
  • 1 291 tis. Kč
    • •
  • AV ČR
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