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59 (0,309s) •

Project

Mitochondrial toxicity of tau protein oligomers and its regulation by drugs for Alzheimer's disease (NU23-04-00032)

, such as the neurotoxic effects of soluble amyloid beta oligomers, the neurotoxic effects of soluble tau protein (tau) oligomers, and mitochondrial dysfunction, are currently being dysfunction caused by soluble tau oligomers

Neurosciences (including psychophysiology)

  • 2023 - 2026
    • •
  • 6 533 tis. Kč
    • •
  • 6 533 tis. Kč
    • •
  • MZ
Project

Synthesis of linear pyridinium-phenylene oligomers for use in molecular electronic (GA203/04/0921)

The aim of the proposed project is the preparation of rigid linear oligomers that will consist of alternating l,4-pyridinium and l ,4-phenylene groups. The length of these oligomers will be up to 30 nm. The methods for preparation t...

CC - Organická chemie

  • 2004 - 2006
    • •
  • 904 tis. Kč
    • •
  • 904 tis. Kč
    • •
  • GA ČR
Project

The synthesis of oligomers with pyridinium cycles for building of molecular electronic circuits (GA203/01/0644)

The aim of the proposed project is the preparation of linear oligomers containing 1,4-phenylene and 1,4-pyridinium groups with the following pattern: ...-phenylene-pyridinium-phenylene-pyridinium-phenylene-... These compounds are to serve as...

CC - Organická chemie

  • 2001 - 2003
    • •
  • 1 075 tis. Kč
    • •
  • 767 tis. Kč
    • •
  • GA ČR
Project

Aniline oligomers and their role in the formation of polyaniline nanostructures –spectroscopic analysis (GAP205/12/0911)

Nanostructured conducting polymeric materials, such as polyaniline, are of exceptional interest due to their potential applications in sensors, actuators, and displays. Aniline oligomers are generally believed to be responsible for the self,...

CD - Makromolekulární chemie

  • 2012 - 2015
    • •
  • 9 006 tis. Kč
    • •
  • 9 006 tis. Kč
    • •
  • GA ČR
Project

Experimental and Theoretical Determination of the Structure of Materials in Atomic Resolution - Polymers, Oligomers, Additives (IAA450412)

9I - 9

  • 1994 - 1996
    • •
  • 382 tis. Kč
    • •
  • 587 tis. Kč
    • •
  • AV ČR
Project

Modification of D-ring of ergot alkaloids and preparation of their oligomers (IAA4020901)

. Biotransformations using yeasts, Streptomycetes and filamentous fungi will be used. Oligomers...

CC - Organická chemie

  • 1999 - 2002
    • •
  • 2 403 tis. Kč
    • •
  • 1 688 tis. Kč
    • •
  • AV ČR
Project

Vibrational spectroscopy and spectroelectrochemistry of the first products formed during conducting polymer preparation (GJ18-01924Y)

and for other conducting polymers. The oligomers are present in low concentrations. This will bring new insights on the oligomers formed during chemical oxidation of aniline on the molecular structure of these oligomers......

Polymer science

  • 2018 - 2020
    • •
  • 3 517 tis. Kč
    • •
  • 3 517 tis. Kč
    • •
  • GA ČR
Project

Photochemical preparation of oligomeric analogues of natural resveratrol derivatives and related stilbenoids (GA203/07/1227)

Resveratrol and its natural oligomers turned to be important food additives for a high-quality human nutrition. They deserve thorough investigation as potential therapeutic substances. Resveratrol is a natural phytoalexin occurring in a numb...

CB - Analytická chemie, separace

  • 2007 - 2009
    • •
  • 1 980 tis. Kč
    • •
  • 1 980 tis. Kč
    • •
  • GA ČR
Project

Biological and antitumor effects of pancreatic ribonuclease A oligomers (GA523/04/0755)

their antitumor effectiveness. Above mentioned oligomers aggregate during lyophilization of RNase A from 40% acetic acid forming tri-, tetra-and higher oligomers. Tri......

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 4 519 tis. Kč
    • •
  • 3 119 tis. Kč
    • •
  • GA ČR
Project

Coordination oligomers and polymers of zinc triad with dithiolates (GA203/07/1657)

The project is aimed at the synthesis and characterization of new molecular, oligomeric, and polymeric compounds of the zinc triad with selected dithiolates. The syntheses will start from mono-, bi-, and trifuctional dithiolates, which are able to fo...

CA - Anorganická chemie

  • 2007 - 2009
    • •
  • 997 tis. Kč
    • •
  • 997 tis. Kč
    • •
  • GA ČR
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