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3 (0,09s)

Project

The Biological and Prognostic Significance of c-erbB-2 Oncogene Expression in Benign and Malignant Breast Lesions. (IZ2924)

FD - Onkologie a hematologie

  • 1995 - 1997
  • 400 tis. Kč
  • 400 tis. Kč
  • MZ
Project

Biosafe plant virus expression system for transient production of human papillomavirus oncoproteins and their use for therapeutic vaccine development (GA521/09/1525)

 The aim of the proposed project is to prepare protein immunogens derived from human papillomavirus HPV16 and optimization of their expression in plants for developing experimental therapeutic anti-HPV16 vaccines. We propose the production of differe...

EI - Biotechnologie a bionika

  • 2009 - 2011
  • 4 792 tis. Kč
  • 4 792 tis. Kč
  • GA ČR
Project

Function of the central domain of oncoprotein Mdm2 and its novel binding partners in the regulation of p53 tumour suppressor protein (GA301/09/1324)

Tumour suppressor p53 is an important regulator of cellular response to stress. Its stability is regulated by oncoprotein Mdm2 which serves as an ubiquitin ligase and targets p53 for degradation in 26S proteasome. Main domains required for Mdm2 funct...

FD - Onkologie a hematologie

  • 2009 - 2011
  • 3 776 tis. Kč
  • 3 776 tis. Kč
  • GA ČR
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