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28 (0,082s) •

Project

IBIS - Inteligent biosensor system for environmental detection of pesticides and herbicides. (FT-TA/089)

Basic research of correlations between output signal of organophosphate methods. The basic research of factors which stimulate the toxicity of organophosphate pesticides and photosyntetic herbicides. The factors which suppress the <...

JB - Senzory, čidla, měření a regulace

  • 2004 - 2007
    • •
  • 14 915 tis. Kč
    • •
  • 11 880 tis. Kč
    • •
  • MPO
Project

*Construction of simple dipstickfor organophosphates assay (FR-TI1/541)

of cholinesterases. Organophosphates and carbamates will be assayed during project solution of organophosphates (carbamates) presence. The main attention will be focused on cholinesterase immobilization and optimization of enzyme a...

CB - Analytická chemie, separace

  • 2009 - 2011
    • •
  • 10 576 tis. Kč
    • •
  • 6 599 tis. Kč
    • •
  • MPO
Project

Development of the effective drug delivery system intended for application in organophosphate poisoning for intranasal administration (FW09020121)

The aim of the project is to develop, evaluate and to transfer into prototype production an original drug used for noninvasive application of active substances in therapy of organophosphate poisoning. Specific aims are: • to design and devel...

Pharmacology and pharmacy

  • 2023 - 2027
    • •
  • 11 780 tis. Kč
    • •
  • 7 643 tis. Kč
    • •
  • TA ČR
Project

Encapsulation of bisquaternary oxime reactivators into solid lipid nanoparticles for enhanced reactivation of cholinesterases in CNS (GA25-15339S)

Quaternary oxime reactivators of cholinesterases are used for life endangering intoxications by organophosphates. They are effective in the peripheral tissues the organophosphates cause irreversible damage of the neuronal tissues, i...

Neurosciences (including psychophysiology)

  • 2025 - 2027
    • •
  • 13 027 tis. Kč
    • •
  • 13 027 tis. Kč
    • •
  • GA ČR
Project

New prospective micellar catalysts for toxic organophosphates hydrolyses (GA203/99/1622)

organophosphates compared to hitherto known micellar catalysts. Their hydrolytic efficiency will be tested by measuring the kinetics of hydrolysis of the toxic organophosphates simulant......

DK - Kontaminace a dekontaminace půdy včetně pesticidů

  • 1999 - 2001
    • •
  • 1 302 tis. Kč
    • •
  • 966 tis. Kč
    • •
  • GA ČR
Project

Modified nucleophiles for reactivation of cholinesterases inhibited by organophosphorus compounds (GA21-03000S)

is forming oximate anion which is able to detoxify organophosphate and restore pseudo-catalytic bioscavenger for scavenging and detoxification of organophosphates......

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2021 - 2023
    • •
  • 10 774 tis. Kč
    • •
  • 10 774 tis. Kč
    • •
  • GA ČR
Project

Biodistribution and real-time monitoring of free or apoferritin-encapsulated charged cholinesterase reactivators (GA22-14568S)

Oxime cholinesterase reactivators are used for life endangering intoxications caused by organophosphate agents. However, clinically used (so called charged to central nervous system, where organophosphates mediate irreversible chang...

Toxicology

  • 2022 - 2024
    • •
  • 11 763 tis. Kč
    • •
  • 11 208 tis. Kč
    • •
  • GA ČR
Project

Field Search for Organophosphate-Resistant Populations of Predator Cheyletus Eruditus to Expand Biological Control of Stored Food Mites (GA509/94/0927)

9B - 9

  • 1994 - 1995
    • •
  • 120 tis. Kč
    • •
  • 240 tis. Kč
    • •
  • GA ČR
Project

Novel butyrylcholinesterase reactivators for pseudo-catalytic scavenging of organophoshates (8F17004)

The project focuses on the research of a new detoxification strategy for organophosphorus compounds using pseudocatalytic scavengers...

FR - Farmakologie a lékárnická chemie

  • 2017 - 2020
    • •
  • 3 222 tis. Kč
    • •
  • 3 222 tis. Kč
    • •
  • MŠMT
Project

Colorimetric sensor for diagnosis of pesticides poisoning (TH03030336)

The project is focused to construction of a colorimetric sensor for a fast diagnosis of pesticides poisoning and it will be suitable for the both human and veterinarian samples. Functional sample of the device will be verified on biological samples. ...

Analytical chemistry

  • 2018 - 2021
    • •
  • 5 092 tis. Kč
    • •
  • 3 053 tis. Kč
    • •
  • TA ČR
  • 1 - 10 out of 28