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877 (0,118s) •

Project

3D and 4D printing of stimuli-responsive and functionally graded biomaterials for osteochondral defects regeneration (GF21-45449L)

Since cartilage and subchondral bone have different biological properties, the therapy of osteochondral defects remains a great challenge. The osteochondral stratified architecture. The osteochondral unit is one a ...

Biomaterials (as related to medical implants, devices, sensors)

  • 2021 - 2026
    • •
  • 4 852 tis. Kč
    • •
  • 4 852 tis. Kč
    • •
  • GA ČR
Project

Allogenic Multipotent Mesenchamal Stromal Cell Spheroids for Cartilage Regeneration Preclinical Evaluation in Porcine Osteochondral Defect Model. (NW25-10-00263)

The use of allogeneic mesenchymal stromal cells (MSCs) for the treatment of osteochondral defects is currently the subject of preclinical and clinical research. Umbilical cord tissue-derived MSCs (WJSC) have emerged as a frequently ...

Orthopaedics

  • 2025 - 2028
    • •
  • 16 761 tis. Kč
    • •
  • 16 761 tis. Kč
    • •
  • MZ
Project

Smart Piezoelectric Bio-based Osteochondral Construct as a Model for Drug Testing and Implantation into Joint Defects (TQ17000008)

SMARTPIEZO aims to develop a Smart Piezoelectric Bio-based Osteochondral Construct (sPiezoBio) as a Model for Drug Testing and implantation into Joint Defects (JD). SMARTPIEZO aligns with the objectives of the funding program with T...

Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

  • 2025 - 2028
    • •
  • 10 733 tis. Kč
    • •
  • 7 513 tis. Kč
    • •
  • TA ČR
Project

Reconstruction of the Joint Surface using autologous osteochondral Grafts, autologous cultured Chondrocytes in Suspension and in bioactive Glass-Ceramic Material. An experimental and clinical Study. (ND6042)

The aim of the project is treatment of deep defects of knee joint cartilage. The project supposes solution of the treatment of joint cartilage. Methods:Cultivation of chondrocytes. Conductivity of bioioactive glass-ceramic materials and morp...

FI - Traumatologie a ortopedie

  • 2000 - 2002
    • •
  • 1 469 tis. Kč
    • •
  • 1 279 tis. Kč
    • •
  • MZ
Project

Novel scaffolds for osteochondral regeneration based on core/shell nanofibers enriched with a drug delivery system (NT12156)

The objective of this study was to establish the system based on core/shell nanofibers enriched with liposomes as a novel drug delivery system for regeneration of osteochondral defects. Liposomes can be fulfilled with growth and dif...

FI - Traumatologie a ortopedie

  • 2011 - 2015
    • •
  • 12 263 tis. Kč
    • •
  • 12 263 tis. Kč
    • •
  • MZ
Project

Human Stem Cells Differentiation in Chondrocytes, Cartilage Mechanical Property - Experimental Study, Part I. (NR8121)

Determination of cartilage model using stem cells extracted from human bone marrow. Determination of the cartilage tissue using cultivated human chondrocytes. Evaluatuin of the basic mechanical properties of the tissue after the human stem cells and ...

FI - Traumatologie a ortopedie

  • 2004 - 2006
    • •
  • 3 418 tis. Kč
    • •
  • 3 235 tis. Kč
    • •
  • MZ
Project

Excellent Research in Regenerative Medicine (EH22_008/0004562)

engineering methods. WP5 aims at the development of treatment of osteochondral defects...

Neurosciences (including psychophysiology)

  • 2023 - 2028
    • •
  • 481 225 tis. Kč
    • •
  • 121 750 tis. Kč
    • •
  • MŠMT
Project

3D printed individualised segmental joint implant optimisation of fixation to bone and biotribology of articular surface (NW25-08-00044)

of osteochondral defects across the human body. The research and development of the segmental that will be customised to the patient, respecting the range and anatomical location of the defect......

Orthopaedics

  • 2025 - 2028
    • •
  • 19 426 tis. Kč
    • •
  • 19 426 tis. Kč
    • •
  • MZ
Project

Coherent x-ray scattering from individual defect in the crystal lattice (IAA101120805)

Defects in the crystalline lattice can be investigated using several methods. Recently, diffusely scattered x-rays are mostly used to study defect within sample. This can be applied only if density of defects in the sample ...

BM - Fyzika pevných látek a magnetismus

  • 2008 - 2010
    • •
  • 1 130 tis. Kč
    • •
  • 1 130 tis. Kč
    • •
  • AV ČR
Project

Hydrogen interaction with defects in zirconia (KJB101120906)

Proposed project deals with characterization of point defects in ZrO2 and investigation of hydrogen interaction with these defects. Defect studies will be performed of defects. Pure ZrO2 is stable in the form of mo...

BM - Fyzika pevných látek a magnetismus

  • 2009 - 2011
    • •
  • 705 tis. Kč
    • •
  • 705 tis. Kč
    • •
  • AV ČR
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