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14 (0,152s) •

Project

Genomic and systems biology profiles as clinical markers of osteoporotic vertebral fractures (NU23-10-00413)

. Early identification of markers of increased risk of osteoporotic fractures could in the bone tissue of the osteoporotic compression vertebral fractures; 2. corresponding contrasting the postmenopausal women who suffered an atraum...

Orthopaedics

  • 2023 - 2026
    • •
  • 9 987 tis. Kč
    • •
  • 9 987 tis. Kč
    • •
  • MZ
Project

Drug delivery systems for treatment of osteoporotic fractures (FW01010662)

The project aims to develop a strategy for osteoporotic therapy. The conventional systems for filling large defects will be enriched by a nanoencapsulated vs conventional therapy by at least 30% in osteoporotic animal - Enhancement ...

Medicinal chemistry

  • 2020 - 2023
    • •
  • 9 927 tis. Kč
    • •
  • 6 896 tis. Kč
    • •
  • TA ČR
Project

Porous gyroid surface structures for improved implant stability in osteoporotic bone (NW24-10-00118)

for better implant fixation in osteoporotic bone could be creation of gyroid porous in contact with the osteoporotic bone. For this purpose, two titanium alloys phases of in vivo tests will be performed on an animal model (5 os...

Biomaterials (as related to medical implants, devices, sensors)

  • 2024 - 2027
    • •
  • 11 554 tis. Kč
    • •
  • 11 554 tis. Kč
    • •
  • MZ
Project

FEMUR (TH01020049)

A set of fixation elements for osteosynthesis of fractures of the femur A set of instrumentation for fractures of the femur...

FI - Traumatologie a ortopedie

  • 2015 - 2018
    • •
  • 24 941 tis. Kč
    • •
  • 14 935 tis. Kč
    • •
  • TA ČR
Project

Development of advanced 3D in vitro model of osteoporosis and investigation of the mechanism of biomaterials osteointegration for bone regeneration (GA18-09306S)

osseointegration in osteoporotic individuals and development of relevant biological models. Up in osteoporotic conditions in vitro is missing. Development of such model will result......

Cell biology

  • 2018 - 2022
    • •
  • 4 975 tis. Kč
    • •
  • 4 852 tis. Kč
    • •
  • GA ČR
Project

Osteoporotic Virtual Physiological Human (7E11016)

Nearly four million osteoporotic bone fractures cost the European health system more than 30 billion Euro per year. This figure could double by 2050. After the first fracture, the chances of having another one increase by 86%. We need to pre...

JC - Počítačový hardware a software

  • 2011 - 2012
    • •
  • 555 tis. Kč
    • •
  • 555 tis. Kč
    • •
  • MŠMT
Project

Simple and inexpensive screening of PRO-HYP dipeptide in non-hydrolyzed urine and its assumed significant role as a biomarker of bone resorption (NR8948)

Based on a smooth and low-cost screening of prolyl-hydroxyproline peptide in non-hydrolyzed urine of osteoporotic female subjects and controls quality of the peptide in reflecting bone status and therapeutic efficacy should be demonstrated.....

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2006 - 2007
    • •
  • 2 010 tis. Kč
    • •
  • 1 364 tis. Kč
    • •
  • MZ
Project

Mechanical properties of estrogen treated rat femora evaluated by tensile and bending tests. (NB5954)

Osteoporotic changes in bone are characterized by changes in both density and structure. Litle is known about the effects of estrogen on bone strength. Ovariectomy is the most popular model for studying the events associated with post-menopa...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
    • •
  • 288 tis. Kč
    • •
  • 272 tis. Kč
    • •
  • MZ
Project

Effects of estrogen status on mechanical properties and biochemical markers of bone turnover in male rats. (NB7508)

Osteoporotic changes in bone are characterized by changes in both density and structure. Little is known about the effects of estrogen on bone metabolism and bone strength in men. Orchidectomy is the most popular model for studying the event...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 1 021 tis. Kč
    • •
  • 1 004 tis. Kč
    • •
  • MZ
Project

Anthropological and epidemiological characterization of Great-Moravian population in connection with the social and economic structure (GA206/03/0725)

), size of osteoporotic changes, appearance of skeleton injuries,content of trace...

EA - Morfologické obory a cytologie

  • 2003 - 2005
    • •
  • 1 418 tis. Kč
    • •
  • 1 418 tis. Kč
    • •
  • GA ČR
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