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4 (0,188s)

Project

Selectively modified betaglucans as immunoactivatory carriers of anticancer drugs for the treatment of colon cancer (NW24-03-00331)

and chemotherapy, often by oxaliplatin. Contrary, immunotherapy based on immune-checkpoint beta-glucans as immunostimulatory carriers of oxaliplatin for the treatment of MSS effects while simultaneously allowing conjugation of ...

Medicinal chemistry

  • 2024 - 2027
  • 15 718 tis. Kč
  • 15 718 tis. Kč
  • MZ
Project

Interactions of organometallic antitumor compounds with nucleic acids and proteins study of sequence and substrate selectivity (GAP208/12/0622)

on the binding of the following complexes to DNA: (1) oxaliplatin, (2) RAPTA-B complex and (3...

CF - Fyzikální chemie a teoretická chemie

  • 2012 - 2015
  • 5 435 tis. Kč
  • 5 435 tis. Kč
  • GA ČR
Project

Advanced Carriers for Platinum Drugs (GA16-05961S)

Novel advanced carriers for platinum drugs and prodrugs will be developed in this project. The carriers will be based on macrocyclic cavitands, molecular capsules, and biocompatible polymers. The drug-carrier systems will be chemically and structural...

CA - Anorganická chemie

  • 2016 - 2020
  • 9 763 tis. Kč
  • 9 763 tis. Kč
  • GA ČR
Project

Functionalized Magnetic Carriers Based on Iron Oxide Nanoparticles with Bonded Biologically Active or Magnetically Interesting Compounds (GAP207/11/0841)

cisplatin, carboplatin and oxaliplatin and involving N6-(benzyl)adenine, 9-deazaguanine...

CA - Anorganická chemie

  • 2011 - 2014
  • 10 020 tis. Kč
  • 6 420 tis. Kč
  • GA ČR
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