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7 336 (0,1s) •

Project

Environment-responsive nanoparticles (IAA100500501)

polymers with surfactants or block copolymers, (b) pH-sensitive supramolecular complexes formed by electrostatic interactions of zwitterionic copolymers of (a) thermoresponsive supramolecular complexes formed eith...

BJ - Termodynamika

  • 2005 - 2008
    • •
  • 1 726 tis. Kč
    • •
  • 1 726 tis. Kč
    • •
  • AV ČR
Project

The role of pH in the development and differentiation of multicellular yeast populations (LTC20036)

) implemented a new method of pH measurement, based on wavelength shifts of pH sensitive “Understanding and exploiting the impact of low pH on microorganisms” aims to develop new approaches for in situ, intracellul...

Microbiology

  • 2020 - 2023
    • •
  • 7 285 tis. Kč
    • •
  • 7 285 tis. Kč
    • •
  • MŠMT
Project

Focusing effects in multidimensional liquid-phase separations (GA18-14893S)

setup, conductivity, pH, application of micellization and complex-forming additives principles. The possibilities of improvement of sensitivity of two-dimensional of industrial samples of complex mixtures.......

Analytical chemistry

  • 2018 - 2022
    • •
  • 3 352 tis. Kč
    • •
  • 2 937 tis. Kč
    • •
  • GA ČR
Project

Functional Characterization of Bacterial Proton-Dependent Manganese Transporters (MntH) using Fluorescence Methods (1K04019)

and of metal substrate resulting from MntH-dependent transport using pH-sensitive ratiometric Green Fluorescent Protein and a metal sensitive fluorescent probe atfurther development and optimisation of sensitive f...

BO - Biofyzika

  • 2004 - 2006
    • •
  • 3 106 tis. Kč
    • •
  • 2 682 tis. Kč
    • •
  • MŠMT
Project

The role of in vitro sensitivity to tyrosine kinase inhibitors estimation in management of patients with chronic myeloid leukemia (NS9949)

Assessment of in vitro sensitivity of leukemic cells from patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors and its implications for the therapy management. Clones of in vitro imatinib-resistant cells, obtained f...

FD - Onkologie a hematologie

  • 2008 - 2010
    • •
  • 3 717 tis. Kč
    • •
  • 3 713 tis. Kč
    • •
  • MZ
Project

Smart pH- and temperaturesensitive hydrogels based on amphiphilic block copolymers with a gradient block (7AMB15FR039)

-(dimethylamino)ethyl acrylate: cationic, pH-and thermo-sensitive). The association behaviourof the copolymers as a function of pH, ionic strength and temperature in pH or/and in temperature. The experimental work ...

CD - Makromolekulární chemie

  • 2015 - 2016
    • •
  • 108 tis. Kč
    • •
  • 108 tis. Kč
    • •
  • MŠMT
Project

Lanthanide complexes as pH sensors for MRL (GP203/01/P006)

Project is focused on synthesis of new ligands derived from 1,4,7,11-tetraazacyclododecane-1,4,7,11-tetraacetic acid, in which one pendant acetate group is substituted by 2-methylpyrimidme or 2-methylpyrazine and on preparation of their complexes...

CA - Anorganická chemie

  • 2001 - 2003
    • •
  • 646 tis. Kč
    • •
  • 583 tis. Kč
    • •
  • GA ČR
Project

Multicompartment Nano-Assemblies for Selective Drug Solubilization and Release (GPP208/12/P236)

charged segments and formation of the interpolyelectrolyte complexes IPECs and microfluidity) will be studied in broad ranges of state parameters (composition, pH, ionic and release of the guest molecules by MCMs we will use model ...

CD - Makromolekulární chemie

  • 2012 - 2014
    • •
  • 1 560 tis. Kč
    • •
  • 1 560 tis. Kč
    • •
  • GA ČR
Project

*Preclinical trials of polymer bound cytostatic and synthesis scale-up transfer from laboratory conditions. (FI-IM2/111)

*Realization of preclinical testing of highly perspective anticancer drug, which is bound via pH-sensitive bond to water-soluble polymer carrier. Further aims include management of its manufacturing at scale-up measure and implement...

FD - Onkologie a hematologie

  • 2005 - 2008
    • •
  • 35 077 tis. Kč
    • •
  • 10 816 tis. Kč
    • •
  • MPO
Project

Spectrum of NGS detected somatic mutations and their association with prognosis and outcome of adolescent and young adult patients with Ph-positive leukemias (NU21-07-00225)

Adolescent and young adult (AYA) patients with Ph+ leukemias comprise a unique aspects and biology of Ph+ leukemias of AYA patients have not been studied in detail landscape of somatic mutations outside the oncogene BCR-ABL1 in ...

Oncology

  • 2021 - 2024
    • •
  • 16 307 tis. Kč
    • •
  • 16 307 tis. Kč
    • •
  • MZ
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